Febuxostat and Rosuvastatin interaction
Febuxostat and Rosuvastatin: the Rosuvastatin prescribing label describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Rosuvastatin (Crestor) label · effective 2026-04-29
Febuxostat Prevention or Management: In patients taking febuxostat, do not exceed a dosage of CRESTOR 20 mg once daily .
Mechanism and Clinical Effect(s): Febuxostat increased rosuvastatin exposure more than 1.9-fold.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.