Fludrocortisone and Repaglinide interaction
Fludrocortisone and Repaglinide: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Fludrocortisone (Fludrocortisone Acetate) label · effective 2026-05-06
Monitor serum potassium levels; use potassium supplements if necessary.
Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary.
Check serum potassium levels at frequent intervals; use potassium supplements if necessary (see WARNINGS ).
Antidiabetic drugs (oral agents and insulin)—diminished antidiabetic effect.
From the Repaglinide label · effective 2025-05-02
Examples: Atypical antipsychotics (e.g., olanzapine and clozapine), calcium channel antagonists, corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), and…
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.