Fludrocortisone and Tacrolimus interaction

Fludrocortisone and Tacrolimus: the Fludrocortisone prescribing label flag this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Fludrocortisone (Fludrocortisone Acetate) label · effective 2026-05-06

Major

Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids.

Warningsby drug classView label on DailyMed
Major

Patients who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or measles and, if exposed, to obtain medical advice.

Precautionsby drug classView label on DailyMed
Minor

Children who are on immunosuppressant drugs are more susceptible to infections than healthy children.

Warningsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.