Fludrocortisone and Ustekinumab interaction
Fludrocortisone and Ustekinumab: both prescribing labels flag this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.
Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.
What the FDA labels say
From the Fludrocortisone (Fludrocortisone Acetate) label · effective 2026-05-06
Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids.
Patients who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or measles and, if exposed, to obtain medical advice.
Children who are on immunosuppressant drugs are more susceptible to infections than healthy children.
From the Ustekinumab (USTEKINUMAB-TTWE) label · effective 2026-01-12
Patients improved with discontinuation of therapy and in certain cases administration of corticosteroids.
In trials in subjects with Crohn's disease (CD-1 and CD-2) and ulcerative colitis (UC-1), immunomodulators (6-MP, AZA, MTX) were used concomitantly in approximately 30% of subjects and corticosteroids were used concomitantly in approximately 40% and 50% of Crohn's disease and ulcerative colitis subjects, respectively.
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Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.