Fluvoxamine and Propafenone interaction
Fluvoxamine and Propafenone: both prescribing labels mention this combination without an instruction to avoid it or change the dose.
Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.
What the FDA labels say
From the Fluvoxamine (fluvoxamine maleate) label · effective 2026-04-23
In vitro data suggest that fluvoxamine is a relatively weak inhibitor of CYP2D6.
From the Propafenone (propafenone hydrochloride) label · effective 2026-01-29
Such drugs may include many antiarrhythmics, some phenothiazines, tricyclic antidepressants, and oral macrolides.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.