Gefitinib and Warfarin interaction

Gefitinib and Warfarin: the Gefitinib prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Gefitinib (IRESSA) label · effective 2023-02-28

Moderate

• Hemorrhage in patients taking warfarin: Monitor changes in prothrombin time or INR.

Drug interactionsnames WarfarinView label on DailyMed
Moderate

Patients taking warfarin should be monitored regularly for changes in prothrombin time or INR.

Drug interactionsnames WarfarinView label on DailyMed
Minor

Hemorrhage in Patients taking Warfarin International Normalized Ratio (INR) elevations and/or hemorrhage have been reported in some patients taking warfarin while on IRESSA therapy.

Drug interactionsnames WarfarinView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.