Grapefruit and Nimodipine interaction

Grapefruit and Nimodipine: the Nimodipine prescribing label flags this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Nimodipine (Nymalize) label · effective 2024-08-30

Major

Avoid grapefruit juice.

Drug interactionsnames GrapefruitView label on DailyMed

Major

Ingestion of grapefruit/grapefruit juice is not recommended while taking nimodipine.

Drug interactionsnames GrapefruitView label on DailyMed

Minor

Grapefruit juice inhibits CYP3A4.

Drug interactionsnames GrapefruitView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.