Guanfacine and Prochlorperazine interaction
Guanfacine and Prochlorperazine: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Guanfacine (Intuniv) label · effective 2025-06-23
Consider the potential for additive sedative effects with CNS depressant drugs.
From the Prochlorperazine (PROCHLORPERAZINE MALEATE) label · effective 2025-07-09
Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.