Halobetasol and Ustekinumab interaction

Halobetasol and Ustekinumab: the Ustekinumab prescribing label mentions this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Ustekinumab (USTEKINUMAB-TTWE) label · effective 2026-01-12

Minor

Patients improved with discontinuation of therapy and in certain cases administration of corticosteroids.

Warnings and precautionsby drug classView label on DailyMed
Minor

In trials in subjects with Crohn's disease (CD-1 and CD-2) and ulcerative colitis (UC-1), immunomodulators (6-MP, AZA, MTX) were used concomitantly in approximately 30% of subjects and corticosteroids were used concomitantly in approximately 40% and 50% of Crohn's disease and ulcerative colitis subjects, respectively.

Drug interactionsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.