Hydralazine and Triamterene and hydrochlorothiazide interaction
Hydralazine and Triamterene and hydrochlorothiazide: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Triamterene and hydrochlorothiazide label · effective 2026-07-16
Thiazides may add to or potentiate the action of other antihypertensive drugs.
See INDICATIONS AND USAGE for concomitant use with other antihypertensive drugs.
From the Hydralazine (hydrALAZINE Hydrochloride) label · effective 2026-08-14
When other potent parenteral antihypertensive drugs, such as diazoxide, are used in combination with hydralazine, patients should be continuously observed for several hours for any excessive fall in blood pressure.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.