Ibuprofen and famotidine and Nizatidine interaction

Ibuprofen and famotidine and Nizatidine: the Ibuprofen and famotidine prescribing label flags this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Ibuprofen and famotidine label · effective 2026-04-07

Major

Ibuprofen and famotidine tablet should not be administered to patients with a history of hypersensitivity to other H 2 -receptor antagonists.

Contraindicationsby drug classView label on DailyMed
Major

Cross sensitivity with other H 2 -receptor antagonists has been observed.

Contraindicationsby drug classView label on DailyMed
Major

Known hypersensitivity to other H 2 -receptor antagonists.

Contraindicationsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.