Imatinib and Levothyroxine interaction

Imatinib and Levothyroxine: the Imatinib prescribing label mentions this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Imatinib (Gleevec) label · effective 2026-07-13

Minor

Hypothyroidism has been reported in thyroidectomy patients undergoing levothyroxine replacement.

Warnings and precautionsnames LevothyroxineView label on DailyMed
Minor

Hypothyroidism Clinical cases of hypothyroidism have been reported in thyroidectomy patients undergoing levothyroxine replacement during treatment with Gleevec.

Warnings and precautionsnames LevothyroxineView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.