Imatinib and Liothyronine interaction

Imatinib and Liothyronine: both prescribing labels mention this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Imatinib (Gleevec) label · effective 2026-07-13

Minor

Hypothyroidism has been reported in thyroidectomy patients undergoing levothyroxine replacement.

Warnings and precautionsby drug classView label on DailyMed
Minor

Hypothyroidism Clinical cases of hypothyroidism have been reported in thyroidectomy patients undergoing levothyroxine replacement during treatment with Gleevec.

Warnings and precautionsby drug classView label on DailyMed

From the Liothyronine (Liothyronine Sodium) label · effective 2026-06-04

Minor

Tyrosine-Kinase Inhibitors Concurrent use of tyrosine-kinase inhibitors such as imatinib may cause hypothyroidism.

Drug interactionsnames ImatinibView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.