Lenalidomide and Tafasitamab interaction

Lenalidomide and Tafasitamab: the Tafasitamab prescribing label flags this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Tafasitamab (MONJUVI) label · effective 2026-02-02

Major

The combination of MONJUVI with lenalidomide is contraindicated in pregnant women because lenalidomide can cause birth defects and death of the unborn child.

Warnings and precautionsnames LenalidomideView label on DailyMed
Moderate

Refer to the lenalidomide prescribing information for dosage modifications.

Warnings and precautionsnames LenalidomideView label on DailyMed
Minor

MONJUVI is initially administered in combination with lenalidomide.

Warnings and precautionsnames LenalidomideView label on DailyMed
Minor

Refer to the lenalidomide prescribing information on use during pregnancy.

Warnings and precautionsnames LenalidomideView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.