Letrozole and Warfarin interaction

Letrozole and Warfarin: the Letrozole prescribing label report no clinically significant interaction between these two.

No interaction

No clinically significant interaction reported. The label studied or considered this pair and found nothing meaningful.

What the FDA labels say

From the Letrozole (Femara) label · effective 2026-06-11

No interaction

Warfarin An interaction study (P017) with warfarin showed no clinically significant effect of letrozole on warfarin pharmacokinetics.

Drug interactionsnames WarfarinView label on DailyMed

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Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.