Levonorgestrel and Teriflunomide interaction

Levonorgestrel and Teriflunomide: the Teriflunomide prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Teriflunomide (Aubagio) label · effective 2026-02-20

Moderate

Teriflunomide may increase exposure of ethinylestradiol and levonorgestrel.

Drug interactionsnames LevonorgestrelView label on DailyMed

Moderate

Effect of AUBAGIO on Oral Contraceptives AUBAGIO may increase the systemic exposures of ethinylestradiol and levonorgestrel.

Drug interactionsby drug classView label on DailyMed

Minor

Choose an appropriate oral contraceptive.

Drug interactionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.