Levothyroxine and Rivaroxaban interaction

Levothyroxine and Rivaroxaban: the Levothyroxine prescribing label describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Levothyroxine (Levothyroxine Sodium) label · effective 2024-07-10

Moderate

Oral Anticoagulants Levothyroxine increases the response to oral anticoagulant therapy.

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Moderate

Therefore, a decrease in the dose of anticoagulant may be warranted with correction of the hypothyroid.

Drug interactionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.