Lithium and Olmesartan interaction

Lithium and Olmesartan: the Olmesartan prescribing label describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Olmesartan (Benicar) label · effective 2025-09-23

Moderate

Lithium: Increases in serum lithium concentrations and lithium toxicity ( 7.4 ).

Drug interactionsnames LithiumView label on DailyMed
Moderate

Lithium Increases in serum lithium concentrations and lithium toxicity have been reported during concomitant administration of lithium with angiotensin II receptor antagonists, including BENICAR.

Drug interactionsnames LithiumView label on DailyMed
Moderate

Monitor serum lithium levels during concomitant use.

Drug interactionsnames LithiumView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.