Meclizine and Paroxetine interaction
Meclizine and Paroxetine: the Meclizine prescribing label mention this combination without an instruction to avoid it or change the dose.
Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.
What the FDA labels say
From the Meclizine (Meclizine Hydrochloride) label · effective 2026-06-12
• CYP2D6 inhibitors: As meclizine is metabolized by CYP2D6, there is a potential for drug-drug interactions between meclizine hydrochloride and CYP2D6 inhibitors ( 7.2 ).
CYP2D6 Inhibitors Based on in-vitro evaluation, meclizine is metabolized by CYP2D6.
Therefore, there is a possibility for a drug interaction between meclizine hydrochloride and CYP2D6 inhibitors.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.