Methimazole and Norethindrone and ethinyl estradiol interaction

Methimazole and Norethindrone and ethinyl estradiol: the Norethindrone and ethinyl estradiol prescribing label describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Norethindrone and ethinyl estradiol (Lo Loestrin Fe) label · effective 2025-03-07

Moderate

Women on thyroid hormone replacement therapy may need increased doses of thyroid hormone because serum concentrations of thyroid binding globulin increase with use of COCs.

Warnings and precautionsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.