Methimazole and Octreotide interaction

Methimazole and Octreotide: the Octreotide prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Octreotide (Mycapssa) label · effective 2025-07-24

Moderate

Thyroid Function Abnormalities MYCAPSSA suppresses the secretion of thyroid-stimulating hormone, which may result in hypothyroidism.

Warnings and precautionsby drug classView label on DailyMed
Minor

Thyroid Function Abnormalities: Hypothyroidism may occur.

Warnings and precautionsby drug classView label on DailyMed
Minor

Assess thyroid function periodically ( 5.3 ).

Warnings and precautionsby drug classView label on DailyMed
Minor

Assess thyroid function periodically during treatment with MYCAPSSA.

Warnings and precautionsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.