Methimazole and Somatropin interaction

Methimazole and Somatropin: the Somatropin prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Somatropin (HUMATROPE) label · effective 2026-08-20

Moderate

Hypothyroidism: Monitor thyroid function periodically as hypothyroidism may occur or worsen after initiation of somatropin.

Warnings and precautionsby drug classView label on DailyMed
Moderate

Patients with Turner syndrome have an inherently increased risk of developing autoimmune thyroid disease and primary hypothyroidism.

Warnings and precautionsby drug classView label on DailyMed
Moderate

Therefore, patients treated with somatropin should have periodic thyroid function tests performed, and thyroid hormone replacement therapy should be initiated or appropriately adjusted when indicated.

Warnings and precautionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.