Metronidazole and Torsemide interaction
Metronidazole and Torsemide: the Torsemide prescribing label describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Torsemide label · effective 2026-07-21
CYP2C9: Concomitant use with CYP2C9 inhibitors can decrease torsemide clearance.
Concomitant use of CYP2C9 inhibitors (e.g., amiodarone, fluconazole, miconazole, oxandrolone) can decrease torsemide clearance and increase torsemide plasma concentrations.
Monitor diuretic effect and blood pressure when used in combination with CYP2C9 inhibitor or inducer.
Cytochrome P450 2C9 Inhibitors and Inducers Torsemide is a substrate of CYP2C9.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.