Mifepristone and Phenobarbital, hyoscyamine, atropine, and scopolamine interaction

Mifepristone and Phenobarbital, hyoscyamine, atropine, and scopolamine: the Mifepristone prescribing label flags this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Mifepristone label · effective 2025-09-25

Major

Avoid co-administration of mifepristone and CYP3A inducers such as rifampin, rifabutin, rifapentin, phenobarbital, phenytoin, carbamazepine, and St.

Drug interactionsnames Phenobarbital, hyoscyamine, atropine, and scopolamineView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.