Mometasone and Montelukast interaction

Mometasone and Montelukast: the Montelukast prescribing label describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Montelukast (SINGULAIR) label · effective 2025-04-30

Moderate

Inhaled corticosteroid may be reduced gradually.

Warnings and precautionsby drug classView label on DailyMed
Moderate

These events have been sometimes associated with the reduction of oral corticosteroid therapy ( 5.5 and 6.2 ).

Warnings and precautionsby drug classView label on DailyMed
Moderate

Concomitant Corticosteroid Use While the dose of inhaled corticosteroid may be reduced gradually under medical supervision, SINGULAIR should not be abruptly substituted for inhaled or oral corticosteroids.

Warnings and precautionsby drug classView label on DailyMed
Moderate

These events have been sometimes associated with the reduction of oral corticosteroid therapy.

Warnings and precautionsby drug classView label on DailyMed
Minor

Do not abruptly substitute SINGULAIR for inhaled or oral corticosteroids ( 5.3 ).

Warnings and precautionsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.