Nevirapine and Verapamil interaction

Nevirapine and Verapamil: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Nevirapine label · effective 2026-07-15

Moderate

Antiarrhythmics: Amiodarone, disopyramide, lidocaine Plasma concentrations may be decreased.

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Moderate

Calcium Channel blockers: Diltiazem, nifedipine, verapamil Plasma concentrations may be decreased.

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From the Verapamil (Verapamil Hydrochloride) label · effective 2025-03-25

Moderate

CYP3A4 inducers decrease verapamil levels ( 7.1 )

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Minor

Inducers of CYP3A4 (e.g., rifampin) have caused a lowering of plasma levels of verapamil.

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Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.