Nevirapine and Warfarin interaction
Nevirapine and Warfarin: the Nevirapine prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Nevirapine label · effective 2026-07-15
As a result, when giving these drugs concomitantly, plasma warfarin levels may change with the potential for increases in coagulation time.
When warfarin is co-administered with nevirapine, anticoagulation levels should be monitored frequently.
Antithrombotics: Warfarin Plasma concentrations may be increased.
The in vitro interaction between nevirapine and the antithrombotic agent warfarin is complex.
Among human hepatic cytochrome P450s, nevirapine was capable in vitro of inhibiting the 10-hydroxylation of (R)-warfarin (CYP3A).
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.