Nisoldipine and Ranitidine interaction

Nisoldipine and Ranitidine: the Nisoldipine prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Nisoldipine (Sular) label · effective 2026-03-12

Moderate

Ranitidine 150 mg twice daily did not interact significantly with nisoldipine (AUC was decreased by 15 - 20%).

Drug interactionsnames RanitidineView label on DailyMed
Minor

No pharmacodynamic effects of either histamine H 2 receptor antagonist were observed.

Drug interactionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.