Phenobarbital, hyoscyamine, atropine, and scopolamine and Rivaroxaban interaction
Phenobarbital, hyoscyamine, atropine, and scopolamine and Rivaroxaban: the Phenobarbital, hyoscyamine, atropine, and scopolamine prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Phenobarbital, hyoscyamine, atropine, and scopolamine (Donnatal) label · effective 2024-12-05
Phenobarbital may decrease the effect of anticoagulants, and necessitate larger doses of the anticoagulant for optimal effect.
When the phenobarbital is discontinued, the dose of the anticoagulant may have to be decreased.
Drug Interactions Phenobarbital may decrease the effect of anticoagulants, and necessitate larger doses of the anticoagulant for optimal effect.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.