Pimozide and Primidone interaction

Pimozide and Primidone: the Pimozide prescribing label mentions this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Pimozide label · effective 2026-08-12

Minor

Pimozide may be capable of potentiating CNS depressants, including analgesics, sedatives, anxiolytics, and alcohol.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.