Pitavastatin and Probenecid and colchicine interaction

Pitavastatin and Probenecid and colchicine: the Pitavastatin prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Pitavastatin (Livalo) label · effective 2026-03-31

Moderate

The following drugs when used concomitantly with LIVALO may also increase the risk of myopathy and rhabdomyolysis: lipid-modifying dosages of niacin (>1grams/day), fibrates, and colchicine [see Drug Interactions (7) ].

Warnings and precautionsnames Probenecid and colchicineView label on DailyMed
Moderate

Intervention: Consider the risk/benefit of concomitant use of colchicine with LIVALO.

Drug interactionsnames Probenecid and colchicineView label on DailyMed
Minor

Colchicine Clinical Impact: Cases of myopathy and rhabdomyolysis have been reported with concomitant use of colchicine with statins, including LIVALO.

Drug interactionsnames Probenecid and colchicineView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.