Plazomicin and Tobramycin interaction

Plazomicin and Tobramycin: the Plazomicin prescribing label mentions this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Plazomicin (Zemdri (plazomicin)) label · effective 2024-12-20

Minor

Before therapy with ZEMDRI is instituted, careful inquiry about previous hypersensitivity reactions to other aminoglycosides should be made.

Warnings and precautionsby drug classView label on DailyMed
Minor

A history of hypersensitivity to other aminoglycosides is a contraindication to the use of ZEMDRI, because cross-sensitivity among aminoglycoside antibacterial drugs has been established.

Warnings and precautionsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.