Prednisone and Rivaroxaban interaction

Prednisone and Rivaroxaban: the Prednisone prescribing label describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Prednisone (Prednisone delayed release) label · effective 2026-04-30

Moderate

Anticoagulant agents: May enhance or diminish anticoagulant effects.

Drug interactionsby drug classView label on DailyMed
Moderate

Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect.

Drug interactionsby drug classView label on DailyMed
Minor

Anticoagulant Agents Co-administration of corticosteroids and warfarin usually results in inhibition of response to warfarin, although there have been some conflicting reports.

Drug interactionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.