Ranitidine and Sodium bicarbonate interaction
Ranitidine and Sodium bicarbonate: the Ranitidine prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Moderate
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Ranitidine label · effective 2022-01-12
Moderate
Gefitinib Gefitinib exposure was reduced by 44% with the coadministration of ranitidine and sodium bicarbonate (dosed to maintain gastric pH above 5.0).
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.