Rosuvastatin and Teriflunomide interaction
Rosuvastatin and Teriflunomide: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Rosuvastatin (Crestor) label · effective 2026-04-29
Teriflunomide Prevention or Management: In patients taking teriflunomide, do not exceed a dosage of CRESTOR 10 mg once daily .
Mechanism and Clinical Effect(s): Teriflunomide increased rosuvastatin exposure more than 2.5-fold.
IMNM is characterized by proximal muscle weakness and elevated serum creatine kinase that persist despite discontinuation of statin treatment; positive anti-HMG CoA reductase antibody; muscle biopsy showing necrotizing myopathy; and improvement with immunosuppressive agents.
Treatment with immunosuppressive agents may be required.
From the Teriflunomide (Aubagio) label · effective 2026-02-20
Rosuvastatin: The dose of rosuvastatin should not exceed 10 mg once daily in patients taking AUBAGIO.
For a patient taking AUBAGIO, the dose of rosuvastatin should not exceed 10 mg once daily.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.