Rosuvastatin and Warfarin interaction
Rosuvastatin and Warfarin: the Rosuvastatin prescribing label describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Rosuvastatin (Crestor) label · effective 2026-04-29
Table 7: CRESTOR Effects on Other Drugs Warfarin Prevention or Management: In patients taking warfarin, obtain an INR before starting CRESTOR and frequently enough after initiation, dosage titration or discontinuation to ensure that no significant alteration in INR occurs.
Mechanism and Clinical Effect(s): Rosuvastatin significantly increased the INR in patients receiving warfarin [see Clinical Pharmacology (12.3) ].
Warfarin : Obtain INR prior to starting CRESTOR.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.