Sodium bicarbonate and Ursodiol interaction
Sodium bicarbonate and Ursodiol: the Ursodiol prescribing label mentions this combination without an instruction to avoid it or change the dose.
Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.
What the FDA labels say
From the Ursodiol (Urso 250) label · effective 2023-01-12
Aluminum-based Antacids : May interfere with the action of URSO 250 and URSO Forte by reducing its absorption.
Aluminum-based Antacids Aluminum-based antacids have been shown to adsorb bile acids in vitro and may be expected to interfere with URSO 250 and URSO Forte in the same manner as the bile acid sequestering agents.
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Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.