Tadalafil and Warfarin interaction

Tadalafil and Warfarin: the Tadalafil prescribing label report no clinically significant interaction between these two.

No interaction

No clinically significant interaction reported. The label studied or considered this pair and found nothing meaningful.

What the FDA labels say

From the Tadalafil (Cialis) label · effective 2026-06-03

No interaction

CYP2C9 (e.g. Warfarin) — Tadalafil had no significant effect on exposure (AUC) to S-warfarin or R-warfarin, nor did tadalafil affect changes in prothrombin time induced by warfarin.

Drug interactionsnames WarfarinView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.