Lewodopa: interakcje

Lewodopa (Inbrija), lek dopaminergiczny: 56 udokumentowanych interakcji w indeksowanych przez nas etykietach FDA i kartach informacyjnych. Poważne: 9, umiarkowane: 46, niewielkie: 1, pary, dla których etykieta nie zgłasza istotnej interakcji: 0. Każda pozycja poniżej cytuje zdanie, na którym się opiera. Ta strona leku to punkt wyjścia, a nie rozstrzygnięcie dla indywidualnej sytuacji.

Interakcje z etykiety

Poważne interakcje (9)

  • Błękit metylenowyinhibitor MAOPoważna

    INBRIJA is contraindicated in patients currently taking a nonselective monoamine oxidase (MAO) inhibitor (e.g., phenelzine and tranylcypromine) or who have recently (within 2 weeks) taken a nonselective MAO inhibitor. (etykieta leku Lewodopa, Przeciwwskazania)

  • Fenelzynainhibitor MAOPoważna

    INBRIJA is contraindicated in patients currently taking a nonselective monoamine oxidase (MAO) inhibitor (e.g., phenelzine and tranylcypromine) or who have recently (within 2 weeks) taken a nonselective MAO inhibitor. (etykieta leku Lewodopa, Przeciwwskazania)

  • IzoniazydantybiotykPoważna

    INBRIJA is contraindicated in patients currently taking a nonselective monoamine oxidase (MAO) inhibitor (e.g., phenelzine and tranylcypromine) or who have recently (within 2 weeks) taken a nonselective MAO inhibitor. (etykieta leku Lewodopa, Przeciwwskazania)

  • KarbidopaPoważna

    Nonselective monoamine oxidase (MAO) inhibitors are contraindicated for use with levodopa or carbidopa-levodopa combination products with or without carbidopa. (etykieta leku Karbidopa, Przeciwwskazania)

  • LinezolidantybiotykPoważna

    INBRIJA is contraindicated in patients currently taking a nonselective monoamine oxidase (MAO) inhibitor (e.g., phenelzine and tranylcypromine) or who have recently (within 2 weeks) taken a nonselective MAO inhibitor. (etykieta leku Lewodopa, Przeciwwskazania)

  • Rasagilinainhibitor MAOPoważna

    INBRIJA is contraindicated in patients currently taking a nonselective monoamine oxidase (MAO) inhibitor (e.g., phenelzine and tranylcypromine) or who have recently (within 2 weeks) taken a nonselective MAO inhibitor. (etykieta leku Lewodopa, Przeciwwskazania)

  • Selegilinainhibitor MAOPoważna

    INBRIJA is contraindicated in patients currently taking a nonselective monoamine oxidase (MAO) inhibitor (e.g., phenelzine and tranylcypromine) or who have recently (within 2 weeks) taken a nonselective MAO inhibitor. (etykieta leku Lewodopa, Przeciwwskazania)

  • TolkaponPoważna

    Tolcapone tablets is also contraindicated in patients with a history of nontraumatic rhabdomyolysis or hyperpyrexia and confusion possibly related to medication (see PRECAUTIONS: Events Reported With Dopaminergic Therapy ). (etykieta leku Tolkapon, Przeciwwskazania)

  • Tranylcyprominainhibitor MAOPoważna

    INBRIJA is contraindicated in patients currently taking a nonselective monoamine oxidase (MAO) inhibitor (e.g., phenelzine and tranylcypromine) or who have recently (within 2 weeks) taken a nonselective MAO inhibitor. (etykieta leku Lewodopa, Przeciwwskazania)

Umiarkowane interakcje (46)

  • Arypiprazollek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Asenapinalek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Brekspiprazollek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Bromokryptynaagonista dopaminyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Bupropionlek przeciwdepresyjnyUmiarkowana

    CNS toxicity has been reported when bupropion was coadministered with levodopa or amantadine. (etykieta leku Bupropion, Interakcje z innymi lekami)

  • Chlorpromazynalek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Cytrynian żelaza(III)lek wiążący fosforanyUmiarkowana

    Dopamine D2 antagonists, isoniazid, and iron salts: May reduce the effectiveness of INBRIJA ( 7.2 , 7.3 ) (etykieta leku Lewodopa, Interakcje z innymi lekami)

  • Deferazyrokssuplement żelazaUmiarkowana

    Dopamine D2 antagonists, isoniazid, and iron salts: May reduce the effectiveness of INBRIJA ( 7.2 , 7.3 ) (etykieta leku Lewodopa, Interakcje z innymi lekami)

  • Deferypronsuplement żelazaUmiarkowana

    Dopamine D2 antagonists, isoniazid, and iron salts: May reduce the effectiveness of INBRIJA ( 7.2 , 7.3 ) (etykieta leku Lewodopa, Interakcje z innymi lekami)

  • Deutetrabenazynainhibitor VMAT2Umiarkowana

    Neuroleptic Malignant Syndrome (NMS) A potentially fatal symptom complex sometimes referred to as Neuroleptic Malignant Syndrome (NMS) has been reported in association with drugs that reduce dopaminergic transmission. (etykieta leku Deutetrabenazyna, Ostrzeżenia i środki ostrożności)

  • DroksydopasympatykomimetykUmiarkowana

    Observe patients carefully when the dosage of NORTHERA is changed or when concomitant levodopa is reduced abruptly or discontinued, especially if the patient is receiving neuroleptics. (etykieta leku Droksydopa, Ostrzeżenia i środki ostrożności)

  • Droperydolantagonista dopaminyUmiarkowana

    Dopamine D2 antagonists, isoniazid, and iron salts: May reduce the effectiveness of INBRIJA ( 7.2 , 7.3 ) (etykieta leku Lewodopa, Interakcje z innymi lekami)

  • EntakaponUmiarkowana

    …Metabolized By Catechol-O-Methyltransferase (COMT) When a single 400 mg dose of entacapone was given with intravenous isoprenaline (isoproterenol) and epinephrine without coadministered levodopa and dopa decarboxylase inhibitor, the overall mean maximal changes in heart rate during infusion were about 50% and 80% higher than with placebo, for isoprenaline and epinephrine,… (etykieta leku Entakapon, Ostrzeżenia)

  • Flufenazynalek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Haloperydollek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Iloperydonlek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Kabergolinaagonista dopaminyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Kariprazynalek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Klozapinalek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Kwetiapinalek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Loksapinalek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Lumateperonlek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Lurazydonlek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Metoklopramidantagonista dopaminyUmiarkowana

    Dopamine D2 Receptor Antagonists and Isoniazid Dopamine D2 receptor antagonists (e.g., phenothiazines, butyrophenones, risperidone, metoclopramide) and isoniazid may reduce the effectiveness of levodopa. (etykieta leku Lewodopa, Interakcje z innymi lekami)

  • Naltrekson + bupropionantagonista receptorów opioidowychUmiarkowana

    CNS toxicity has been reported when bupropion was coadministered with levodopa or amantadine. (etykieta leku Naltrekson + bupropion, Interakcje z innymi lekami)

  • Olanzapinalek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Olanzapina + fluoksetynalek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Paliperydonlek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Perfenazynalek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Pimawanserynalek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Pimozydlek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Pramipeksolagonista dopaminyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Prochlorperazynalek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Ropinirolagonista dopaminyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Rysperydonlek przeciwpsychotycznyUmiarkowana

    Dopamine D2 Receptor Antagonists and Isoniazid Dopamine D2 receptor antagonists (e.g., phenothiazines, butyrophenones, risperidone, metoclopramide) and isoniazid may reduce the effectiveness of levodopa. (etykieta leku Lewodopa, Interakcje z innymi lekami)

  • SapropterynaUmiarkowana

    Interaction with Levodopa : Seizures, over-stimulation or irritability may occur; monitor patients for a change in neurologic status. (etykieta leku Sapropteryna, Ostrzeżenia i środki ostrożności)

  • SepiapterynaUmiarkowana

    Interaction with Levodopa : Seizures, over-stimulation or irritability may occur; monitor patients for a change in neurologic status. (etykieta leku Sepiapteryna, Ostrzeżenia i środki ostrożności)

  • Solriamfetollek pobudzający OUNUmiarkowana

    Drugs that Increase Blood Pressure and/or Heart Rate and Dopaminergic Drugs : Use caution when co-administering with SUNOSI. (etykieta leku Solriamfetol, Interakcje z innymi lekami)

  • Tetrabenazynainhibitor VMAT2Umiarkowana

    Neuroleptic Malignant Syndrome (NMS) A potentially fatal symptom complex sometimes referred to as Neuroleptic Malignant Syndrome (NMS) has been reported in association with tetrabenazine tablets and other drugs that reduce dopaminergic transmission [see Drug Interactions (7.6) ]. (etykieta leku Tetrabenazyna, Ostrzeżenia i środki ostrożności)

  • Tiorydazynalek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Tiotyksenlek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Trifluoperazynalek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • Triheksyfenidyllek przeciwcholinergicznyUmiarkowana

    The usual dose of either trihexyphenidyl or levodopa may need to be reduced during concomitant therapy, since concomitant administration may increase drug-induced involuntary movements (See DOSAGE AND ADMINISTRATION ). (etykieta leku Triheksyfenidyl, Interakcje z innymi lekami)

  • Walbenazynainhibitor VMAT2Umiarkowana

    Neuroleptic Malignant Syndrome (NMS ) A potentially fatal symptom complex referred to as Neuroleptic Malignant Syndrome (NMS) has been reported in association with drugs that reduce dopaminergic transmission. (etykieta leku Walbenazyna, Ostrzeżenia i środki ostrożności)

  • Zyprazydonlek przeciwpsychotycznyUmiarkowana

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etykieta leku Lewodopa, Ostrzeżenia i środki ostrożności)

  • ŻelazoWitaminy i minerałyUmiarkowana

    Dopamine D2 antagonists, isoniazid, and iron salts: May reduce the effectiveness of INBRIJA ( 7.2 , 7.3 ) (etykieta leku Lewodopa, Interakcje z innymi lekami)

Wzmianki o niewielkim znaczeniu (1)

  • Karbidopa + lewodopa + entakaponlek dopaminergicznyNiewielka

    The expected incidence of fibrotic complications is so low that even if entacapone caused these complications at rates similar to those attributable to other dopaminergic therapies, it is unlikely that it would have been detected in a cohort of the size exposed to entacapone during its clinical development. (etykieta leku Karbidopa + lewodopa + entakapon, Ostrzeżenia i środki ostrożności)

Sprawdź, jak Lewodopa łączy się ze wszystkim, co przyjmujesz. Dodaj całą listę; wszystkie pary są sprawdzane jednocześnie.

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To nie jest porada medyczna. Stopień nasilenia odzwierciedla sformułowania etykiety, a nie indywidualne okoliczności. Oznaczenie „poważna” może dotyczyć połączenia stosowanego rutynowo pod nadzorem, a „niewielka” może mieć znaczenie przy dużych dawkach. Należy zapytać farmaceutę.