Liotyronina: interakcje

Liotyronina (Cytomel), hormon tarczycy: 282 udokumentowane interakcje w indeksowanych przez nas etykietach FDA i kartach informacyjnych. Poważne: 64, umiarkowane: 177, niewielkie: 40, pary, dla których etykieta nie zgłasza istotnej interakcji: 1. Każda pozycja poniżej cytuje zdanie, na którym się opiera. Ta strona leku to punkt wyjścia, a nie rozstrzygnięcie dla indywidualnej sytuacji.

Interakcje z etykiety

Poważne interakcje (64)

  • AdrenalinasympatykomimetykPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Amfepramon (dietylopropion)lek pobudzający OUNPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Amfetaminalek pobudzający OUNPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Amfetamina + deksamfetaminalek pobudzający OUNPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Arformoterolagonista receptorów beta-adrenergicznychPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Armodafinillek pobudzający OUNPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Artykaina + adrenalinaśrodek znieczulający miejscowoPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Benzfetaminalek pobudzający OUNPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Brymonidyna + tymololagonista receptorów alfa-adrenergicznychPoważna

    Patients suspected of developing thyrotoxicosis should be managed carefully to avoid abrupt withdrawal of beta-adrenergic blocking agents that might precipitate a thyroid storm. (etykieta leku Brymonidyna + tymolol, Ostrzeżenia i środki ostrożności)

  • Budezonid + formoterolkortykosteroidPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Bupiwakaina + adrenalinaśrodek znieczulający miejscowoPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Presence of uncontrolled non-gonadal endocrinopathies (e.g., thyroid, adrenal, or pituitary disorders). (etykieta leku Choriogonadotropina alfa, Przeciwwskazania)

  • DeksametazonkortykosteroidPoważna

    When concomitant administration of corticosteroids and levothyroxine is required, administration of corticosteroid should precede the initiation of levothyroxine therapy to avoid adrenal crisis. (etykieta leku Deksametazon, Ostrzeżenia i środki ostrożności)

  • Deksamfetaminalek pobudzający OUNPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Deksmetylofenidatlek pobudzający OUNPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • DobutaminasympatykomimetykPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Dorzolamid + tymololinhibitor anhydrazy węglanowejPoważna

    Patients suspected of developing thyrotoxicosis should be managed carefully to avoid abrupt withdrawal of beta-adrenergic blocking agents that might precipitate a thyroid storm. (etykieta leku Dorzolamid + tymolol, Ostrzeżenia i środki ostrożności)

  • DroksydopasympatykomimetykPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Dulaglutydagonista receptora GLP-1Poważna

    WARNING: RISK OF THYROID C-CELL TUMORS In male and female rats, dulaglutide causes a dose-related and treatment-duration-dependent increase in the incidence of thyroid C-cell tumors (adenomas and carcinomas) after lifetime exposure. (etykieta leku Dulaglutyd, Ostrzeżenie w ramce)

  • EfedrynasympatykomimetykPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Ergotamina + kofeinaalkaloid sporyszuPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Fendimetrazynalek pobudzający OUNPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Fenterminalek pobudzający OUNPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Fentermina + topiramatlek pobudzający OUNPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Fenylefrynalek obkurczający błonę śluzową nosaPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Flutykazon + salmeterolkortykosteroidPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • FolitropinaPoważna

    Reactions including anaphylaxis have been reported [see Adverse Reactions (6.2) ] High levels of FSH indicating primary gonadal failure Presence of uncontrolled non-gonadal endocrinopathies (e.g., thyroid, adrenal, or pituitary disorders) [see Indications and Usage (1.1 , 1.2 , 1.3) ] Hypersensitivity reactions to streptomycin or neomycin. (etykieta leku Folitropina, Przeciwwskazania)

  • Formoterolagonista receptorów beta-adrenergicznychPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Ipratropium + salbutamollek przeciwcholinergicznyPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Izoprenalinaagonista receptorów beta-adrenergicznychPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Klomifenselektywny modulator receptora estrogenowegoPoważna

    Clomiphene citrate tablets are contraindicated in patients with uncontrolled thyroid or adrenal dysfunction or in the presence of an organic intracranial lesion such as pituitary tumor (see INDICATIONS AND USAGE). (etykieta leku Klomifen, Przeciwwskazania)

  • Lewosalbutamolagonista receptorów beta-adrenergicznychPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Lidokaina + adrenalinaśrodek znieczulający miejscowoPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Liraglutydagonista receptora GLP-1Poważna

    WARNING: RISK OF THYROID C-CELL TUMORS • Liraglutide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures in both genders of rats and mice. (etykieta leku Liraglutyd, Ostrzeżenie w ramce)

  • Lisdeksamfetaminalek pobudzający OUNPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Metamfetaminalek pobudzający OUNPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Metylofenidatlek pobudzający OUNPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Midodrynaagonista receptorów alfa-adrenergicznychPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Mirabegronagonista receptorów beta-adrenergicznychPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Modafinillek pobudzający OUNPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Nadololbeta-blokerPoważna

    Patients suspected of developing thyrotoxicosis should be managed carefully to avoid abrupt withdrawal of beta-adrenergic blockade which might precipitate a thyroid storm. (etykieta leku Nadolol, Ostrzeżenia)

  • Oksymetazolinalek obkurczający błonę śluzową nosaPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Orfenadryna + kwas acetylosalicylowy + kofeinalek zwiotczający mięśniePoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Pindololbeta-blokerPoważna

    Patients suspected of developing thyrotoxicosis should be managed carefully to avoid abrupt withdrawal of beta-blockade which might precipitate a thyroid crisis. (etykieta leku Pindolol, Ostrzeżenia)

  • Propranololbeta-blokerPoważna

    Avoid abrupt withdrawal of beta-blockade, which may precipitate a thyroid storm. (etykieta leku Propranolol, Ostrzeżenia i środki ostrożności)

  • Prylokaina + adrenalinaśrodek znieczulający miejscowoPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Pseudoefedrynalek obkurczający błonę śluzową nosaPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Salbutamolagonista receptorów beta-adrenergicznychPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Salmeterolagonista receptorów beta-adrenergicznychPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Semaglutydagonista receptora GLP-1Poważna

    WARNING: RISK OF THYROID C-CELL TUMORS • In rodents, semaglutide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures. (etykieta leku Semaglutyd, Ostrzeżenie w ramce)

  • Solriamfetollek pobudzający OUNPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Sotalolbeta-blokerPoważna

    Thyroid Abnormalities Avoid abrupt withdrawal of beta-blockade which might be followed by an exacerbation of symptoms of hyperthyroidism, including thyroid storm. (etykieta leku Sotalol, Ostrzeżenia i środki ostrożności)

  • Terbutalinaagonista receptorów beta-adrenergicznychPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Tranylcyprominainhibitor MAOPoważna

    People who have thyroid problems (hyperthyroidism) may have a higher chance of having a hypertensive crisis. (etykieta leku Tranylcypromina, Ostrzeżenie w ramce)

  • Tymololbeta-blokerPoważna

    Patients suspected of developing thyrotoxicosis should be managed carefully to avoid abrupt withdrawal of beta-adrenergic blocking agents that might precipitate a thyroid storm. (etykieta leku Tymolol, Ostrzeżenia i środki ostrożności)

  • Tyrzepatydagonista receptora GLP-1Poważna

    WARNING: RISK OF THYROID C-CELL TUMORS In rats, tirzepatide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures. (etykieta leku Tyrzepatyd, Ostrzeżenie w ramce)

  • Umeklidynium + wilanterollek przeciwcholinergicznyPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

  • Węglan lantanulek wiążący fosforanyPoważna

    Do not take thyroid hormone replacement therapy within 2 hours of dosing with LANTHANUM CARBONATE. (etykieta leku Węglan lantanu, Interakcje z innymi lekami)

  • Wibegronagonista receptorów beta-adrenergicznychPoważna

    • Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see Adverse Reactions (6) , Drug Interactions (7.7) , and Overdosage (10) ] . (etykieta leku Liotyronina, Ostrzeżenie w ramce)

Umiarkowane interakcje (177)

  • Acebutololbeta-blokerUmiarkowana

    Drug or Drug Class Effect Beta-adrenergic antagonists (e.g., Propranolol >160 mg/day) In patients treated with large doses of propranolol (>160 mg/day), T3 and T4 levels change, TSH levels remain normal, and patients are clinically euthyroid. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Akarbozalek przeciwcukrzycowyUmiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • AksytynibUmiarkowana

    Monitor thyroid function before initiation of, and periodically throughout, treatment with INLYTA. (etykieta leku Aksytynib, Ostrzeżenia i środki ostrożności)

  • Alogliptynainhibitor DPP-4Umiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Alogliptyna + metforminainhibitor DPP-4Umiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Amiodaronlek przeciwarytmicznyUmiarkowana

    Other drugs: Amiodarone Amiodarone inhibits peripheral conversion of levothyroxine (T4) to triiodothyronine (T3) and may cause isolated biochemical changes (increase in serum free-T4, and decreased or normal free-T3) in clinically euthyroid patients. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Amitryptylinatrójpierścieniowy lek przeciwdepresyjnyUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Amoksapinatrójpierścieniowy lek przeciwdepresyjnyUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Apiksabanlek przeciwzakrzepowyUmiarkowana

    Oral Anticoagulants Liothyronine sodium increases the response to oral anticoagulant therapy. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Argatrobanlek przeciwzakrzepowyUmiarkowana

    Oral Anticoagulants Liothyronine sodium increases the response to oral anticoagulant therapy. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Atenololbeta-blokerUmiarkowana

    Drug or Drug Class Effect Beta-adrenergic antagonists (e.g., Propranolol >160 mg/day) In patients treated with large doses of propranolol (>160 mg/day), T3 and T4 levels change, TSH levels remain normal, and patients are clinically euthyroid. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Atenolol + chlortalidonbeta-blokerUmiarkowana

    Drug or Drug Class Effect Beta-adrenergic antagonists (e.g., Propranolol >160 mg/day) In patients treated with large doses of propranolol (>160 mg/day), T3 and T4 levels change, TSH levels remain normal, and patients are clinically euthyroid. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Azelastyna + flutykazonlek przeciwhistaminowyUmiarkowana

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • BalsalazydsalicylanUmiarkowana

    An initial increase in serum FT4 is followed by return of FT4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T4 levels may decrease by as much as 30%. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • BeklometazonkortykosteroidUmiarkowana

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • BeksarotenretinoidUmiarkowana

    Monitor and replace thyroid hormone if needed. (etykieta leku Beksaroten, Ostrzeżenia i środki ostrożności)

  • Betaksololbeta-blokerUmiarkowana

    Drug or Drug Class Effect Beta-adrenergic antagonists (e.g., Propranolol >160 mg/day) In patients treated with large doses of propranolol (>160 mg/day), T3 and T4 levels change, TSH levels remain normal, and patients are clinically euthyroid. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • BetametazonkortykosteroidUmiarkowana

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Bexagliflozininhibitor SGLT2Umiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • BikalutamidandrogenUmiarkowana

    Androgens/Anabolic Steroids Asparaginase Glucocorticoids Slow-Release Nicotinic Acid These drugs may decrease serum TBG concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Bisoprololbeta-blokerUmiarkowana

    Drug or Drug Class Effect Beta-adrenergic antagonists (e.g., Propranolol >160 mg/day) In patients treated with large doses of propranolol (>160 mg/day), T3 and T4 levels change, TSH levels remain normal, and patients are clinically euthyroid. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Bisoprolol + hydrochlorotiazydbeta-blokerUmiarkowana

    Drug or Drug Class Effect Beta-adrenergic antagonists (e.g., Propranolol >160 mg/day) In patients treated with large doses of propranolol (>160 mg/day), T3 and T4 levels change, TSH levels remain normal, and patients are clinically euthyroid. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Biwalirudynalek przeciwzakrzepowyUmiarkowana

    Oral Anticoagulants Liothyronine sodium increases the response to oral anticoagulant therapy. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • BudezonidkortykosteroidUmiarkowana

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Bupropionlek przeciwdepresyjnyUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • CyklezonidkortykosteroidUmiarkowana

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • CytalopramSSRIUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Dabigatranlek przeciwzakrzepowyUmiarkowana

    Oral Anticoagulants Liothyronine sodium increases the response to oral anticoagulant therapy. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • DanazolandrogenUmiarkowana

    Androgens/Anabolic Steroids Asparaginase Glucocorticoids Slow-Release Nicotinic Acid These drugs may decrease serum TBG concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Dapagliflozynainhibitor SGLT2Umiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Dapagliflozyna + metforminainhibitor SGLT2Umiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • DeflazakortkortykosteroidUmiarkowana

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • DeswenlafaksynaSNRIUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Dezogestrel + etynyloestradioldoustny środek antykoncepcyjnyUmiarkowana

    Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • DezonidkortykosteroidUmiarkowana

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Dezypraminatrójpierścieniowy lek przeciwdepresyjnyUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • DiflunisalNLPZUmiarkowana

    An initial increase in serum FT4 is followed by return of FT4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T4 levels may decrease by as much as 30%. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Digoksynaglikozyd naparstnicyUmiarkowana

    Digitalis Glycosides Liothyronine sodium may reduce the therapeutic effects of digitalis glycosides. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Dioctan etynodiolu + etynyloestradioldoustny środek antykoncepcyjnyUmiarkowana

    Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Doksepinatrójpierścieniowy lek przeciwdepresyjnyUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Drospirenon + etynyloestradioldoustny środek antykoncepcyjnyUmiarkowana

    Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • DuloksetynaSNRIUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Edoksabanlek przeciwzakrzepowyUmiarkowana

    Oral Anticoagulants Liothyronine sodium increases the response to oral anticoagulant therapy. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Eksenatydagonista receptora GLP-1Umiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Empagliflozynainhibitor SGLT2Umiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Empagliflozyna + metforminainhibitor SGLT2Umiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Enoksaparynalek przeciwzakrzepowyUmiarkowana

    Oral Anticoagulants Liothyronine sodium increases the response to oral anticoagulant therapy. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • EscytalopramSSRIUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Eslikarbazepinalek przeciwdrgawkowyUmiarkowana

    Abnormal Thyroid Function Tests Dose-dependent decreases in serum T3 and T4 (free and total) values have been observed in patients taking APTIOM. (etykieta leku Eslikarbazepina, Ostrzeżenia i środki ostrożności)

  • Esmololbeta-blokerUmiarkowana

    Drug or Drug Class Effect Beta-adrenergic antagonists (e.g., Propranolol >160 mg/day) In patients treated with large doses of propranolol (>160 mg/day), T3 and T4 levels change, TSH levels remain normal, and patients are clinically euthyroid. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • EstradiolestrogenUmiarkowana

    Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Estradiol + dienogestdoustny środek antykoncepcyjnyUmiarkowana

    Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Estradiol + noretysteronestrogenUmiarkowana

    Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Estrogeny skoniugowaneestrogenUmiarkowana

    Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Fenelzynainhibitor MAOUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • FenobarbitalbarbituranUmiarkowana

    Drug or Drug Class Effect Phenobarbital Rifampin Phenobarbital has been shown to reduce the response to thyroxine. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Drug or Drug Class Effect Phenobarbital Rifampin Phenobarbital has been shown to reduce the response to thyroxine. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Fenytoinalek przeciwdrgawkowyUmiarkowana

    Phenytoin and carbamazepine reduce serum protein binding of thyroid hormones, and total and FT4 may be reduced by 20% to 40%, but most patients have normal serum TSH levels and are clinically euthyroid. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • FludrokortyzonkortykosteroidUmiarkowana

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • FlunizolidkortykosteroidUmiarkowana

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • FluocynonidkortykosteroidUmiarkowana

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • FluoksetynaSSRIUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • FluorouracylantymetabolitUmiarkowana

    Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • FlutamidandrogenUmiarkowana

    Androgens/Anabolic Steroids Asparaginase Glucocorticoids Slow-Release Nicotinic Acid These drugs may decrease serum TBG concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • FlutykazonkortykosteroidUmiarkowana

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • FluwoksaminaSSRIUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Fondaparynukslek przeciwzakrzepowyUmiarkowana

    Oral Anticoagulants Liothyronine sodium increases the response to oral anticoagulant therapy. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • FulwestrantestrogenUmiarkowana

    Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Furosemiddiuretyk pętlowyUmiarkowana

    Furosemide has been shown to inhibit the protein binding of T4 to TBG and albumin, causing an increased free-T4 fraction in serum. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Glibenklamidpochodna sulfonylomocznikaUmiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Glibenklamid + metforminapochodna sulfonylomocznikaUmiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Glimepirydpochodna sulfonylomocznikaUmiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Glipizydpochodna sulfonylomocznikaUmiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Glipizyd + metforminapochodna sulfonylomocznikaUmiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • HalobetazolkortykosteroidUmiarkowana

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Heparynalek przeciwzakrzepowyUmiarkowana

    Oral Anticoagulants Liothyronine sodium increases the response to oral anticoagulant therapy. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • HialuronidazaUmiarkowana

    …recommended that appropriate references first be consulted to determine the usual precautions for the use of the other drug; e.g., when epinephrine is injected along with hyaluronidase, the precautions for the use of epinephrine in cardiovascular disease, thyroid disease, diabetes, digital nerve block, ischemia of the fingers and toes etc., should be observed. (etykieta leku Hialuronidaza, Interakcje z innymi lekami)

  • HydrokortyzonkortykosteroidUmiarkowana

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Imipraminatrójpierścieniowy lek przeciwdepresyjnyUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Insulina aspartinsulinaUmiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Insulina degludecinsulinaUmiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Insulina detemirinsulinaUmiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Insulina glargineinsulinaUmiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Insulina lisproinsulinaUmiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Thyroid function should be monitored periodically. (etykieta leku Interferon beta-1a, Ostrzeżenia i środki ostrożności)

  • Kanagliflozynainhibitor SGLT2Umiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Karbamazepinalek przeciwdrgawkowyUmiarkowana

    Phenytoin and carbamazepine reduce serum protein binding of thyroid hormones, and total and FT4 may be reduced by 20% to 40%, but most patients have normal serum TSH levels and are clinically euthyroid. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Karwedilolbeta-blokerUmiarkowana

    Drug or Drug Class Effect Beta-adrenergic antagonists (e.g., Propranolol >160 mg/day) In patients treated with large doses of propranolol (>160 mg/day), T3 and T4 levels change, TSH levels remain normal, and patients are clinically euthyroid. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • KlobetazolkortykosteroidUmiarkowana

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Klomipraminatrójpierścieniowy lek przeciwdepresyjnyUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Kolesewelamsekwestrant kwasów żółciowychUmiarkowana

    Drug or Drug Class Effect Bile Acid Sequestrants -Colesevelam -Cholestyramine -Colestipol Ion Exchange Resins -Kayexalate -Sevelamer Bile acid sequestrants and ion exchange resins are known to decrease thyroid hormones absorption. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Kolestypolsekwestrant kwasów żółciowychUmiarkowana

    Drug or Drug Class Effect Bile Acid Sequestrants -Colesevelam -Cholestyramine -Colestipol Ion Exchange Resins -Kayexalate -Sevelamer Bile acid sequestrants and ion exchange resins are known to decrease thyroid hormones absorption. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Kolestyraminasekwestrant kwasów żółciowychUmiarkowana

    Drug or Drug Class Effect Bile Acid Sequestrants -Colesevelam -Cholestyramine -Colestipol Ion Exchange Resins -Kayexalate -Sevelamer Bile acid sequestrants and ion exchange resins are known to decrease thyroid hormones absorption. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Kwas acetylosalicylowyNLPZUmiarkowana

    An initial increase in serum FT4 is followed by return of FT4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T4 levels may decrease by as much as 30%. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Kwas acetylosalicylowy + dipirydamollek przeciwpłytkowyUmiarkowana

    An initial increase in serum FT4 is followed by return of FT4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T4 levels may decrease by as much as 30%. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Kwas alendronowybisfosfonianUmiarkowana

    Levothyroxine The bioavailability of alendronate was slightly decreased when BINOSTO and levothyroxine were co-administered to healthy subjects [see Clinical Pharmacology (12.3) ] . (etykieta leku Kwas alendronowy, Interakcje z innymi lekami)

  • Kwetiapinalek przeciwpsychotycznyUmiarkowana

    Hypothyroidism Adults: Clinical trials with quetiapine demonstrated dose-related decreases in thyroid hormone levels. (etykieta leku Kwetiapina, Ostrzeżenia i środki ostrożności)

  • Labetalolbeta-blokerUmiarkowana

    Drug or Drug Class Effect Beta-adrenergic antagonists (e.g., Propranolol >160 mg/day) In patients treated with large doses of propranolol (>160 mg/day), T3 and T4 levels change, TSH levels remain normal, and patients are clinically euthyroid. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • LanreotydUmiarkowana

    Thyroid Function Abnormalities : Decreases in thyroid function may occur; perform tests where clinically indicated. (etykieta leku Lanreotyd, Ostrzeżenia i środki ostrożności)

  • LewomilnacypranSNRIUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • LewonorgestrelprogestagenUmiarkowana

    Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Lewonorgestrel + etynyloestradioldoustny środek antykoncepcyjnyUmiarkowana

    Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Lewotyroksynahormon tarczycyUmiarkowana

    Other drugs: Amiodarone Amiodarone inhibits peripheral conversion of levothyroxine (T4) to triiodothyronine (T3) and may cause isolated biochemical changes (increase in serum free-T4, and decreased or normal free-T3) in clinically euthyroid patients. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Linagliptynainhibitor DPP-4Umiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Linagliptyna + metforminainhibitor DPP-4Umiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Litlek serotoninergicznyUmiarkowana

    • Hypothyroidism and Hyperthyroidism: Monitor thyroid function regularly ( 5.7 ). (etykieta leku Lit, Ostrzeżenia i środki ostrożności)

  • MedroksyprogesteronprogestagenUmiarkowana

    Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • MegestrolprogestagenUmiarkowana

    Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Mentol + salicylan metylusalicylanUmiarkowana

    An initial increase in serum FT4 is followed by return of FT4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T4 levels may decrease by as much as 30%. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • MesalazynasalicylanUmiarkowana

    An initial increase in serum FT4 is followed by return of FT4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T4 levels may decrease by as much as 30%. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • MetadonopioidUmiarkowana

    Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • MetforminabiguanidUmiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Metoprololbeta-blokerUmiarkowana

    Drug or Drug Class Effect Beta-adrenergic antagonists (e.g., Propranolol >160 mg/day) In patients treated with large doses of propranolol (>160 mg/day), T3 and T4 levels change, TSH levels remain normal, and patients are clinically euthyroid. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Metoprolol + hydrochlorotiazydbeta-blokerUmiarkowana

    Drug or Drug Class Effect Beta-adrenergic antagonists (e.g., Propranolol >160 mg/day) In patients treated with large doses of propranolol (>160 mg/day), T3 and T4 levels change, TSH levels remain normal, and patients are clinically euthyroid. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • MetyloprednizolonkortykosteroidUmiarkowana

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • MetylotestosteronandrogenUmiarkowana

    Androgens/Anabolic Steroids Asparaginase Glucocorticoids Slow-Release Nicotinic Acid These drugs may decrease serum TBG concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Mifeprystoninhibitor CYP3A4Umiarkowana

    Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Miglitollek przeciwcukrzycowyUmiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Mirtazapinalek przeciwdepresyjnyUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Mitotaninduktor CYP3A4Umiarkowana

    Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • MometazonkortykosteroidUmiarkowana

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Naltrekson + bupropionantagonista receptorów opioidowychUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • NateglinidmeglitynidUmiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Nebiwololbeta-blokerUmiarkowana

    Drug or Drug Class Effect Beta-adrenergic antagonists (e.g., Propranolol >160 mg/day) In patients treated with large doses of propranolol (>160 mg/day), T3 and T4 levels change, TSH levels remain normal, and patients are clinically euthyroid. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Nefazodonlek przeciwdepresyjnyUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • NoretysteronprogestagenUmiarkowana

    Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Noretysteron + etynyloestradioldoustny środek antykoncepcyjnyUmiarkowana

    Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Norgestrel + etynyloestradioldoustny środek antykoncepcyjnyUmiarkowana

    Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Norgestymat + etynyloestradioldoustny środek antykoncepcyjnyUmiarkowana

    Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Nortryptylinatrójpierścieniowy lek przeciwdepresyjnyUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • OktreotydUmiarkowana

    Thyroid Function Abnormalities MYCAPSSA suppresses the secretion of thyroid-stimulating hormone, which may result in hypothyroidism. (etykieta leku Oktreotyd, Ostrzeżenia i środki ostrożności)

  • Olanzapina + fluoksetynalek przeciwpsychotycznyUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Olopatadyna + mometazonlek przeciwhistaminowyUmiarkowana

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • OrlistatUmiarkowana

    Drug Interactions and Decreased Vitamin Absorption ORLISTAT may interact with concomitant drugs including cyclosporine, levothyroxine, warfarin, amiodarone, antiepileptic drugs, and antiretroviral drugs [see Drug Interactions (7) ]. (etykieta leku Orlistat, Ostrzeżenia i środki ostrożności)

  • ParoksetynaSSRIUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • PasyreotydUmiarkowana

    Monitoring pituitary function (e.g., thyroid, adrenal, gonadal) prior to initiation of therapy with SIGNIFOR LAR, as well as periodically during treatment, as clinically appropriate, is recommended. (etykieta leku Pasyreotyd, Ostrzeżenia i środki ostrożności)

  • PazopanibUmiarkowana

    Hypothyroidism : Monitor thyroid tests at baseline, during treatment and as clinically indicated and manage hypothyroidism as appropriate. (etykieta leku Pazopanib, Ostrzeżenia i środki ostrożności)

  • PioglitazontiazolidynodionUmiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Pioglitazon + glimepirydtiazolidynodionUmiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Pioglitazon + metforminatiazolidynodionUmiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Polistyrenosulfonian sodusuplement potasuUmiarkowana

    Drug or Drug Class Effect Bile Acid Sequestrants -Colesevelam -Cholestyramine -Colestipol Ion Exchange Resins -Kayexalate -Sevelamer Bile acid sequestrants and ion exchange resins are known to decrease thyroid hormones absorption. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • PrednizolonkortykosteroidUmiarkowana

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • PrednizonkortykosteroidUmiarkowana

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • ProgesteronprogestagenUmiarkowana

    Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Protryptylinatrójpierścieniowy lek przeciwdepresyjnyUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • RepaglinidmeglitynidUmiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • RyfampicynaantybiotykUmiarkowana

    Drug or Drug Class Effect Phenobarbital Rifampin Phenobarbital has been shown to reduce the response to thyroxine. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • RyfapentynaantybiotykUmiarkowana

    …levonorgestrel Immunosuppressants Cyclosporine, tacrolimus Methylxanthines Theophylline Narcotic analgesics Methadone Phosphodiesterase-5 (PDE-5) Inhibitors Sildenafil Thyroid preparations Levothyroxine Tricyclic antidepressants Amitriptyline, nortriptyline 7.5 Other Interactions The conversion of PRIFTIN to 25-desacetyl rifapentine is mediated by an esterase enzyme. (etykieta leku Ryfapentyna, Interakcje z innymi lekami)

  • Rywaroksabanlek przeciwzakrzepowyUmiarkowana

    Oral Anticoagulants Liothyronine sodium increases the response to oral anticoagulant therapy. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Saksagliptynainhibitor DPP-4Umiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Saksagliptyna + metforminainhibitor DPP-4Umiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • SalsalatNLPZUmiarkowana

    An initial increase in serum FT4 is followed by return of FT4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T4 levels may decrease by as much as 30%. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • SertralinaSSRIUmiarkowana

    Administration of sertraline in patients stabilized on liothyronine sodium may result in increased liothyronine sodium requirements. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Sewelamerlek wiążący fosforanyUmiarkowana

    Drug or Drug Class Effect Bile Acid Sequestrants -Colesevelam -Cholestyramine -Colestipol Ion Exchange Resins -Kayexalate -Sevelamer Bile acid sequestrants and ion exchange resins are known to decrease thyroid hormones absorption. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • SomatropinaUmiarkowana

    Hypothyroidism: Monitor thyroid function periodically as hypothyroidism may occur or worsen after initiation of somatropin. (etykieta leku Somatropina, Ostrzeżenia i środki ostrożności)

  • SorafenibUmiarkowana

    • Impairment of Thyroid Stimulating Hormone Suppression (TSH) in DTC : Monitor TSH monthly and adjust thyroid replacement therapy in patients with thyroid cancer. (etykieta leku Sorafenib, Ostrzeżenia i środki ostrożności)

  • SulfasalazynasulfonamidUmiarkowana

    An initial increase in serum FT4 is followed by return of FT4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T4 levels may decrease by as much as 30%. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • SunitynibUmiarkowana

    • Thyroid Dysfunction : Monitor thyroid function at baseline, periodically during treatment, and as clinically indicated. (etykieta leku Sunitynib, Ostrzeżenia i środki ostrożności)

  • Sytagliptynainhibitor DPP-4Umiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Sytagliptyna + metforminainhibitor DPP-4Umiarkowana

    • Worsening of diabetic control: Therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Tamoksyfenselektywny modulator receptora estrogenowegoUmiarkowana

    Table 2: Drugs That May Alter Triiodothyronine (T3) Serum Transport Without Affecting Free Thyroxine (FT4) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • TestosteronandrogenUmiarkowana

    Androgens/Anabolic Steroids Asparaginase Glucocorticoids Slow-Release Nicotinic Acid These drugs may decrease serum TBG concentration. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Trazodonlek przeciwdepresyjnyUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • TriamcynolonkortykosteroidUmiarkowana

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Trimipraminatrójpierścieniowy lek przeciwdepresyjnyUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • WapńWitaminy i minerałyUmiarkowana

    Suplementy wapnia mogą zmniejszać wchłanianie tych leków; należy je przyjmować w odstępie kilku godzin. (NIH Office of Dietary Supplements, Calcium)

  • Warfarynalek przeciwzakrzepowyUmiarkowana

    Oral Anticoagulants Liothyronine sodium increases the response to oral anticoagulant therapy. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • WenlafaksynaSNRIUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • WilazodonSSRIUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Wortioksetynalek przeciwdepresyjnyUmiarkowana

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Zasadowy salicylan bizmutusalicylanUmiarkowana

    An initial increase in serum FT4 is followed by return of FT4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T4 levels may decrease by as much as 30%. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • ŻelazoWitaminy i minerałyUmiarkowana

    Żelazo zmniejsza wchłanianie tych leków; należy je przyjmować w odstępie kilku godzin. (NIH Office of Dietary Supplements, Iron)

Wzmianki o niewielkim znaczeniu (40)

  • BusulfanNiewielka

    Cytologic abnormalities characterized by giant, hyperchromatic nuclei have been reported in lymph nodes, pancreas, thyroid, adrenal glands, liver, and bone marrow. (etykieta leku Busulfan, Ostrzeżenia)

  • Butalbital + paracetamolbarbituranNiewielka

    Changes in thyroid status may occur if barbiturates are added or withdrawn from patients being treated for hypothyroidism. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • CelekoksybNLPZNiewielka

    Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Cyklofosfamidlek immunosupresyjnyNiewielka

    Secondary malignancies (urinary tract cancer, myelodysplasia, acute leukemias, lymphomas, thyroid cancer, and sarcomas) have been reported in patients treated with cyclophosphamide-containing regimens . (etykieta leku Cyklofosfamid, Ostrzeżenia i środki ostrożności)

  • Losartan, glipizide and levothyroxine did not show any changes in exposure when co-administered with LOKELMA. (etykieta leku Cyklokrzemian sodowo-cyrkonowy, Interakcje z innymi lekami)

  • CysteaminaNiewielka

    Other Medications Used for the Management of Fanconi Syndrome PROCYSBI can be administered with other electrolyte and mineral replacements necessary for management of Fanconi syndrome, as well as vitamin D and thyroid hormone. (etykieta leku Cysteamina, Interakcje z innymi lekami)

  • DiklofenakNLPZNiewielka

    Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Diwalproeks (walproinian)lek przeciwdrgawkowyNiewielka

    Effect on Ketone and Thyroid Function Tests Valproate is partially eliminated in the urine as a keto-metabolite which may lead to a false interpretation of the urine ketone test. (etykieta leku Diwalproeks (walproinian), Ostrzeżenia i środki ostrożności)

  • EtodolakNLPZNiewielka

    Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • FenoprofenNLPZNiewielka

    Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • FlurbiprofenNLPZNiewielka

    Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Hydrokodon + ibuprofenopioidNiewielka

    Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • IbuprofenNLPZNiewielka

    Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • IfosfamidNiewielka

    Cases of myelodysplastic syndrome, acute leukemias, lymphomas, thyroid cancers, and sarcomas have occurred and may develop several years after chemotherapy has been discontinued. (etykieta leku Ifosfamid, Ostrzeżenia i środki ostrożności)

  • Imatynibinhibitor CYP3A4Niewielka

    Tyrosine-Kinase Inhibitors Concurrent use of tyrosine-kinase inhibitors such as imatinib may cause hypothyroidism. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • IndometacynaNLPZNiewielka

    Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Jodek potasuNiewielka

    Warnings Potassium iodide can cause fetal harm, abnormal thyroid function, and goiter when administered to a pregnant woman. (etykieta leku Jodek potasu, Ostrzeżenia)

  • Ketaminalek działający depresyjnie na OUNNiewielka

    Ketamine Concurrent use of ketamine and liothyronine sodium may produce marked hypertension and tachycardia. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • KetoprofenNLPZNiewielka

    Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • KetorolakNLPZNiewielka

    Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Kwas mefenamowyNLPZNiewielka

    Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Kwas walproinowylek przeciwdrgawkowyNiewielka

    Effect on Ketone and Thyroid Function Tests Valproate is partially eliminated in the urine as a keto-metabolite which may lead to a false interpretation of the urine ketone test. (etykieta leku Kwas walproinowy, Ostrzeżenia i środki ostrożności)

  • Kwas zoledronowybisfosfonianNiewielka

    Hypocalcemia and Mineral Metabolism Preexisting hypocalcemia and disturbances of mineral metabolism (e.g., hypoparathyroidism, thyroid surgery, parathyroid surgery; malabsorption syndromes, excision of small intestine) must be effectively treated before initiating therapy with Reclast. (etykieta leku Kwas zoledronowy, Ostrzeżenia i środki ostrożności)

  • LenalidomidNiewielka

    Thyroid Disorders Both hypothyroidism and hyperthyroidism have been reported [see Adverse Reactions (6.2) ] . (etykieta leku Lenalidomid, Ostrzeżenia i środki ostrożności)

  • MeloksykamNLPZNiewielka

    Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • MetoheksitalbarbituranNiewielka

    Changes in thyroid status may occur if barbiturates are added or withdrawn from patients being treated for hypothyroidism. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Minocyklinaantybiotyk tetracyklinowyNiewielka

    EMROSI may induce hyperpigmentation in many organs, including nails, bone, skin, eyes, thyroid, visceral tissue, oral cavity (teeth, mucosa, alveolar bone), sclerae and heart valves. (etykieta leku Minocyklina, Ostrzeżenia i środki ostrożności)

  • NabumetonNLPZNiewielka

    Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • NaproksenNLPZNiewielka

    Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • OksaprozynaNLPZNiewielka

    Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Pilokarpinaagonista cholinergicznyNiewielka

    …performed, the following concomitant drugs were used in at least 10% of patients in either or both Sjogren's efficacy studies: acetylsalicylic acid, artificial tears, calcium, conjugated estrogens, hydroxychloroquine sulfate, ibuprofen, levothyroxine sodium, medroxyprogesterone acetate, methotrexate, multivitamins, naproxen, omeprazole, paracetamol, and prednisone. (etykieta leku Pilokarpina, Interakcje z innymi lekami)

  • PiroksykamNLPZNiewielka

    Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Prymidonlek przeciwdrgawkowyNiewielka

    Changes in thyroid status may occur if barbiturates are added or withdrawn from patients being treated for hypothyroidism. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • SulindakNLPZNiewielka

    Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • Sumatryptan + naproksentryptanNiewielka

    Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

  • TolmetynaNLPZNiewielka

    Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (etykieta leku Liotyronina, Interakcje z innymi lekami)

Nie zgłoszono istotnej interakcji (1)

  • Montelukastantagonista receptora leukotrienowegoBrak interakcji

    …adjustment is needed when SINGULAIR is co-administered with theophylline, prednisone, prednisolone, oral contraceptives, fexofenadine, digoxin, warfarin, gemfibrozil, itraconazole, thyroid hormones, sedative hypnotics, non-steroidal anti-inflammatory agents, benzodiazepines, decongestants, and Cytochrome P450 (CYP) enzyme inducers [see Clinical Pharmacology (12.3)… (etykieta leku Montelukast, Interakcje z innymi lekami)

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To nie jest porada medyczna. Stopień nasilenia odzwierciedla sformułowania etykiety, a nie indywidualne okoliczności. Oznaczenie „poważna” może dotyczyć połączenia stosowanego rutynowo pod nadzorem, a „niewielka” może mieć znaczenie przy dużych dawkach. Należy zapytać farmaceutę.