Błękit metylenowy: interakcje

Błękit metylenowy (ProvayBlue), inhibitor MAO: 204 udokumentowane interakcje w indeksowanych przez nas etykietach FDA i kartach informacyjnych. Poważne: 122, umiarkowane: 59, niewielkie: 23, pary, dla których etykieta nie zgłasza istotnej interakcji: 0. Każda pozycja poniżej cytuje zdanie, na którym się opiera. Ta strona leku to punkt wyjścia, a nie rozstrzygnięcie dla indywidualnej sytuacji.

Interakcje z etykiety

Poważne interakcje (122)

  • AlmotryptantryptanPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Amfepramon (dietylopropion)lek pobudzający OUNPoważna

    During or within 14 days following the administration of monoamine oxidase inhibitors, hypertensive crises may result. (etykieta leku Amfepramon (dietylopropion), Przeciwwskazania)

  • Amfetaminalek pobudzający OUNPoważna

    Patients taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because of an increased risk of hypertensive crisis [ see Warnings and Precautions (5.7) , Drug Interactions (7.1) ]. (etykieta leku Amfetamina, Przeciwwskazania)

  • Amfetamina + deksamfetaminalek pobudzający OUNPoważna

    Hypersensitivity reactions such as angioedema and anaphylactic reactions have been reported in patients treated with other amphetamine products [see Adverse Reactions ( 6.2 )] . taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because of an increased risk of hypertensive… (etykieta leku Amfetamina + deksamfetamina, Przeciwwskazania)

  • Amitryptylinatrójpierścieniowy lek przeciwdepresyjnyPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Amoksapinatrójpierścieniowy lek przeciwdepresyjnyPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Apraklonidynaagonista receptorów alfa-adrenergicznychPoważna

    CONTRAINDICATIONS IOPIDINE 1% Ophthalmic Solution is contraindicated for patients receiving monoamine oxidase inhibitor therapy and for patients with hypersensitivity to any component of this medication or to clonidine. (etykieta leku Apraklonidyna, Przeciwwskazania)

  • Atomoksetynainhibitor wychwytu zwrotnego noradrenalinyPoważna

    Avoid concomitant use of PROVAYBLUE with selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), monoamine oxidase inhibitors (MAOIs) and opioids. [see Warnings and Precautions ( 5.1 ) and Drug Interactions ( 7.1 )]. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Benzfetaminalek pobudzający OUNPoważna

    Hypertensive crises have resulted when sympathomimetic amines have been used concomitantly or within 14 days following use of monoamine oxidase inhibitors. (etykieta leku Benzfetamina, Przeciwwskazania)

  • Opioids and dextromethorphan may increase the risk of developing serotonin syndrome. (etykieta leku Błękit metylenowy, Ostrzeżenia i środki ostrożności)

  • BuprenorfinaopioidPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Bupropionlek przeciwdepresyjnyPoważna

    Avoid concomitant use of PROVAYBLUE with medicinal products that enhance serotonergic transmission including antidepressants like SSRIs (selective serotonin reuptake inhibitors), SNRIs (serotonin and norepinephrine reuptake inhibitors), MAOIs (monoamine oxidase inhibitors), bupropion, buspirone, clomipramine, mirtazapine, linezolid, opioids, and dextromethorphan… (etykieta leku Błękit metylenowy, Interakcje z innymi lekami)

  • Buspironlek serotoninergicznyPoważna

    …including antidepressants like SSRIs (selective serotonin reuptake inhibitors), SNRIs (serotonin and norepinephrine reuptake inhibitors), MAOIs (monoamine oxidase inhibitors), bupropion, buspirone, clomipramine, mirtazapine, linezolid, opioids, and dextromethorphan because of the potential for serious CNS reactions, including potentially fatal serotonin syndrome. (etykieta leku Błękit metylenowy, Interakcje z innymi lekami)

  • WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • ButorfanolopioidPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Cyklobenzaprynalek zwiotczający mięśniePoważna

    Clinically significant drug interactions with PROVAYBLUE are described below: The concomitant use of PROVAYBLUE with other drugs that affect the serotonergic neurotransmitter system has resulted in serotonin syndrome. (etykieta leku Błękit metylenowy, Interakcje z innymi lekami)

  • Cyproheptadynalek przeciwhistaminowyPoważna

    Monoamine oxidase inhibitor therapy (See DRUG INTERACTIONS ). (etykieta leku Cyproheptadyna, Przeciwwskazania)

  • CytalopramSSRIPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Deksamfetaminalek pobudzający OUNPoważna

    Patients taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because of an increased risk of hypertensive crisis [see Warnings and Drug Interactions ]. (etykieta leku Deksamfetamina, Przeciwwskazania)

  • Dekschlorfeniraminalek przeciwhistaminowyPoważna

    Antihistamines are also contraindicated in the following conditions: Hypersensitivity to dexchlorpheniramine maleate or other antihistamines of similar chemical structure Monoamine oxidase inhibitor therapy (See Drug Interaction section) (etykieta leku Dekschlorfeniramina, Przeciwwskazania)

  • Deksmetylofenidatlek pobudzający OUNPoważna

    • Concomitant treatment with monoamine oxidase inhibitors (MAOIs) or within 14 days following discontinuation of treatment with an MAOI, because of the risk of hypertensive crises [see Drug Interactions ( 7.1 )] . (etykieta leku Deksmetylofenidat, Przeciwwskazania)

  • Dekstrometorfanlek serotoninergicznyPoważna

    Opioids and dextromethorphan may increase the risk of developing serotonin syndrome. (etykieta leku Błękit metylenowy, Ostrzeżenia i środki ostrożności)

  • Dekstrometorfan + chinidynalek serotoninergicznyPoważna

    Opioids and dextromethorphan may increase the risk of developing serotonin syndrome. (etykieta leku Błękit metylenowy, Ostrzeżenia i środki ostrożności)

  • DeswenlafaksynaSNRIPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Deutetrabenazynainhibitor VMAT2Poważna

    Taking monoamine oxidase inhibitors (MAOIs). (etykieta leku Deutetrabenazyna, Przeciwwskazania)

  • Dezypraminatrójpierścieniowy lek przeciwdepresyjnyPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Avoid use of diphenoxylate hydrochloride and atropine sulfate in patients who take MAOIs and monitor for signs and symptoms of hypertensive crisis (headache, hyperthermia, hypertension). (etykieta leku Difenoksylat + atropina, Interakcje z innymi lekami)

  • Dihydroergotaminaalkaloid sporyszuPoważna

    Clinically significant drug interactions with PROVAYBLUE are described below: The concomitant use of PROVAYBLUE with other drugs that affect the serotonergic neurotransmitter system has resulted in serotonin syndrome. (etykieta leku Błękit metylenowy, Interakcje z innymi lekami)

  • Doksepinatrójpierścieniowy lek przeciwdepresyjnyPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Doksylamina + pirydoksynalek przeciwhistaminowyPoważna

    …Known hypersensitivity to doxylamine succinate, other ethanolamine derivative antihistamines, pyridoxine hydrochloride or any inactive ingredient in the formulation Monoamine oxidase (MAO) inhibitors intensify and prolong the adverse central nervous system effects of doxylamine succinate and pyridoxine hydrochloride delayed-release tablets [ see Drug Interactions… (etykieta leku Doksylamina + pirydoksyna, Przeciwwskazania)

  • DroksydopasympatykomimetykPoważna

    However, based on mechanism of action, the use of non-selective MAO inhibitors and linezolid should be avoided as there is a potential for increased blood pressure when taken with NORTHERA. (etykieta leku Droksydopa, Interakcje z innymi lekami)

  • DuloksetynaSNRIPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • DziurawiecZioła i suplementyPoważna

    Łączenie dziurawca z lekami przeciwdepresyjnymi i innymi lekami serotoninergicznymi zwiększa ryzyko zespołu serotoninowego. (NCCIH, St. John's Wort)

  • EletryptantryptanPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • EluksadolinaopioidPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • EscytalopramSSRIPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Fendimetrazynalek pobudzający OUNPoważna

    …coronary artery disease, stroke, arrhythmias, congestive heart failure, uncontrolled hypertension, pulmonary hypertension) • During or within 14 days following the administration of monoamine oxidase inhibitors • Hyperthyroidism • Glaucoma • Agitated states • History of drug abuse • Pregnancy (see PRECAUTIONS, Pregnancy ) • Nursing • Use in combination with other… (etykieta leku Fendimetrazyna, Przeciwwskazania)

  • Fenelzynainhibitor MAOPoważna

    Clinically significant drug interactions with PROVAYBLUE are described below: The concomitant use of PROVAYBLUE with other drugs that affect the serotonergic neurotransmitter system has resulted in serotonin syndrome. (etykieta leku Błękit metylenowy, Interakcje z innymi lekami)

  • FentanylopioidPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Fenterminalek pobudzający OUNPoważna

    …cardiovascular disease (e.g., coronary artery disease, stroke, arrhythmias, congestive heart failure, uncontrolled hypertension) • During or within 14 days following the administration of monoamine oxidase inhibitors • Hyperthyroidism • Glaucoma • Agitated states • History of drug abuse • Pregnancy [ see Use in Specific Populations () ] • Nursing [ see Use in Specific… (etykieta leku Fentermina, Przeciwwskazania)

  • Fentermina + topiramatlek pobudzający OUNPoważna

    …Warnings and Precautions (5.1) and Use in Specific Populations (8.1) ] With glaucoma [see Warnings and Precautions (5.3) ] With hyperthyroidism Taking or within 14 days of stopping a monoamine oxidase inhibitors [see Drug Interactions (7) ] With known hypersensitivity to phentermine, topiramate or any of the excipients in phentermine and topiramate extended-release… (etykieta leku Fentermina + topiramat, Przeciwwskazania)

  • Flibanserynalek działający depresyjnie na OUNPoważna

    Clinically significant drug interactions with PROVAYBLUE are described below: The concomitant use of PROVAYBLUE with other drugs that affect the serotonergic neurotransmitter system has resulted in serotonin syndrome. (etykieta leku Błękit metylenowy, Interakcje z innymi lekami)

  • FluoksetynaSSRIPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • FluwoksaminaSSRIPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • FrowatryptantryptanPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Granisetronlek wydłużający odstęp QTPoważna

    Clinically significant drug interactions with PROVAYBLUE are described below: The concomitant use of PROVAYBLUE with other drugs that affect the serotonergic neurotransmitter system has resulted in serotonin syndrome. (etykieta leku Błękit metylenowy, Interakcje z innymi lekami)

  • HydrokodonopioidPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • HydromorfonopioidPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Imipraminatrójpierścieniowy lek przeciwdepresyjnyPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Karbamazepinalek przeciwdrgawkowyPoważna

    Concomitant use of monoamine oxidase inhibitors (MAOIs). (etykieta leku Karbamazepina, Przeciwwskazania)

  • KarbidopaPoważna

    Nonselective monoamine oxidase (MAO) inhibitors are contraindicated for use with levodopa or carbidopa-levodopa combination products with or without carbidopa. (etykieta leku Karbidopa, Przeciwwskazania)

  • Karbidopa + lewodopalek dopaminergicznyPoważna

    DUOPA is contraindicated in patients who are currently taking a nonselective monoamine oxidase (MAO) inhibitor (e.g., phenelzine and tranylcypromine) or have recently (within 2 weeks) taken a nonselective MAO inhibitor. (etykieta leku Karbidopa + lewodopa, Przeciwwskazania)

  • Karbidopa + lewodopa + entakaponlek dopaminergicznyPoważna

    Carbidopa, levodopa and entacapone tablets is contraindicated in patients: Taking nonselective monoamine oxidase (MAO) inhibitors (e.g., phenelzine and tranylcypromine). (etykieta leku Karbidopa + lewodopa + entakapon, Przeciwwskazania)

  • Karbinoksaminalek przeciwhistaminowyPoważna

    …because deaths have been reported in this age group [see Warnings and Precautions (5.1)]. patients who are hypersensitive to carbinoxamine maleate or any of the inactive ingredients in Carbinoxamine Maleate Extended-Release Oral Suspension [see Warnings and Precautions (5.4)]. patients who are taking monoamine oxidase inhibitors (MAOI) [see Drug Interactions (7)]. (etykieta leku Karbinoksamina, Przeciwwskazania)

  • Klomipraminatrójpierścieniowy lek przeciwdepresyjnyPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • KodeinaopioidPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Lewodopalek dopaminergicznyPoważna

    INBRIJA is contraindicated in patients currently taking a nonselective monoamine oxidase (MAO) inhibitor (e.g., phenelzine and tranylcypromine) or who have recently (within 2 weeks) taken a nonselective MAO inhibitor. (etykieta leku Lewodopa, Przeciwwskazania)

  • LewomilnacypranSNRIPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • LeworfanolopioidPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • LinezolidantybiotykPoważna

    …including antidepressants like SSRIs (selective serotonin reuptake inhibitors), SNRIs (serotonin and norepinephrine reuptake inhibitors), MAOIs (monoamine oxidase inhibitors), bupropion, buspirone, clomipramine, mirtazapine, linezolid, opioids, and dextromethorphan because of the potential for serious CNS reactions, including potentially fatal serotonin syndrome. (etykieta leku Błękit metylenowy, Interakcje z innymi lekami)

  • Lisdeksamfetaminalek pobudzający OUNPoważna

    Patients taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because of an increased risk of hypertensive crisis [see Warnings and Precautions (5.7) and Drug Interactions (7.1) ] . (etykieta leku Lisdeksamfetamina, Przeciwwskazania)

  • Litlek serotoninergicznyPoważna

    Clinically significant drug interactions with PROVAYBLUE are described below: The concomitant use of PROVAYBLUE with other drugs that affect the serotonergic neurotransmitter system has resulted in serotonin syndrome. (etykieta leku Błękit metylenowy, Interakcje z innymi lekami)

  • MetadonopioidPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Metaksalonlek zwiotczający mięśniePoważna

    Serotonin syndrome has resulted from concomitant use of metaxalone (within the recommended dosage range) and other serotonergic drugs [see Warnings and Precautions (5.1) ]. (etykieta leku Metaksalon, Interakcje z innymi lekami)

  • Metamfetaminalek pobudzający OUNPoważna

    Hypersensitivity reactions such as angioedema and anaphylactic reactions have been reported in patients treated with other amphetamine products [see Adverse Reactions ( 6 )]. taking monoamine oxidase inhibitors (MAOIs), or within 14 days following discontinuation of treatment with an MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because… (etykieta leku Metamfetamina, Przeciwwskazania)

  • Metoklopramidantagonista dopaminyPoważna

    In one study in hypertensive patients, intravenously administered metoclopramide was shown to release catecholamines; hence, avoid use in patients with hypertension or in patients taking monoamine oxidase inhibitors [see Drug Interactions ( 7.1 )] . (etykieta leku Metoklopramid, Ostrzeżenia i środki ostrożności)

  • Metyldopalek przeciwnadciśnieniowyPoważna

    CONTRAINDICATIONS Methyldopa is contraindicated in patients: – with active hepatic disease, such as acute hepatitis and active cirrhosis. – with liver disorders previously associated with methyldopa therapy (see WARNINGS ). – with hypersensitivity to any component of this product. – on therapy with monoamine oxidase (MAO) inhibitors. (etykieta leku Metyldopa, Przeciwwskazania)

  • Metylofenidatlek pobudzający OUNPoważna

    Concomitant treatment with monoamine oxidase inhibitors (MAOIs), and also within a minimum of 14 days following discontinuation of treatment with a monoamine oxidase inhibitor because of the risk of hypertensive crisis [see Drug Interactions (7.1) ]. (etykieta leku Metylofenidat, Przeciwwskazania)

  • Midodrynaagonista receptorów alfa-adrenergicznychPoważna

    Avoid use of MAO inhibitors or linezolid with midodrine. (etykieta leku Midodryna, Interakcje z innymi lekami)

  • MilnacypranSNRIPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Mirtazapinalek przeciwdepresyjnyPoważna

    Clinically significant drug interactions with PROVAYBLUE are described below: The concomitant use of PROVAYBLUE with other drugs that affect the serotonergic neurotransmitter system has resulted in serotonin syndrome. (etykieta leku Błękit metylenowy, Interakcje z innymi lekami)

  • MorfinaopioidPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • NalbufinaopioidPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Naltrekson + bupropionantagonista receptorów opioidowychPoważna

    Avoid concomitant use of PROVAYBLUE with medicinal products that enhance serotonergic transmission including antidepressants like SSRIs (selective serotonin reuptake inhibitors), SNRIs (serotonin and norepinephrine reuptake inhibitors), MAOIs (monoamine oxidase inhibitors), bupropion, buspirone, clomipramine, mirtazapine, linezolid, opioids, and dextromethorphan… (etykieta leku Błękit metylenowy, Interakcje z innymi lekami)

  • NaratryptantryptanPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Nefazodonlek przeciwdepresyjnyPoważna

    Clinically significant drug interactions with PROVAYBLUE are described below: The concomitant use of PROVAYBLUE with other drugs that affect the serotonergic neurotransmitter system has resulted in serotonin syndrome. (etykieta leku Błękit metylenowy, Interakcje z innymi lekami)

  • Nortryptylinatrójpierścieniowy lek przeciwdepresyjnyPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • OksykodonopioidPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • OksymorfonopioidPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Olanzapina + fluoksetynalek przeciwpsychotycznyPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • OlicerydynaopioidPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Ondansetronlek wydłużający odstęp QTPoważna

    Clinically significant drug interactions with PROVAYBLUE are described below: The concomitant use of PROVAYBLUE with other drugs that affect the serotonergic neurotransmitter system has resulted in serotonin syndrome. (etykieta leku Błękit metylenowy, Interakcje z innymi lekami)

  • Palonosetronlek serotoninergicznyPoważna

    Clinically significant drug interactions with PROVAYBLUE are described below: The concomitant use of PROVAYBLUE with other drugs that affect the serotonergic neurotransmitter system has resulted in serotonin syndrome. (etykieta leku Błękit metylenowy, Interakcje z innymi lekami)

  • Paracetamol + kodeinaopioidPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • ParoksetynaSSRIPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • PetydynaopioidPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Prometazyna + dekstrometorfanlek przeciwhistaminowyPoważna

    Opioids and dextromethorphan may increase the risk of developing serotonin syndrome. (etykieta leku Błękit metylenowy, Ostrzeżenia i środki ostrożności)

  • Prometazyna + kodeinaopioidPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Protryptylinatrójpierścieniowy lek przeciwdepresyjnyPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Prukaloprydlek serotoninergicznyPoważna

    Clinically significant drug interactions with PROVAYBLUE are described below: The concomitant use of PROVAYBLUE with other drugs that affect the serotonergic neurotransmitter system has resulted in serotonin syndrome. (etykieta leku Błękit metylenowy, Interakcje z innymi lekami)

  • Pseudoefedrynalek obkurczający błonę śluzową nosaPoważna

    Warnings Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. (etykieta leku Pseudoefedryna, Ostrzeżenia)

  • Rasagilinainhibitor MAOPoważna

    Clinically significant drug interactions with PROVAYBLUE are described below: The concomitant use of PROVAYBLUE with other drugs that affect the serotonergic neurotransmitter system has resulted in serotonin syndrome. (etykieta leku Błękit metylenowy, Interakcje z innymi lekami)

  • RemifentanylopioidPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • RyzatryptantryptanPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Selegilinainhibitor MAOPoważna

    Clinically significant drug interactions with PROVAYBLUE are described below: The concomitant use of PROVAYBLUE with other drugs that affect the serotonergic neurotransmitter system has resulted in serotonin syndrome. (etykieta leku Błękit metylenowy, Interakcje z innymi lekami)

  • SertralinaSSRIPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Solriamfetollek pobudzający OUNPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • SumatryptantryptanPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • TapentadolopioidPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Tetrabenazynainhibitor VMAT2Poważna

    • Taking monoamine oxidase inhibitors (MAOIs). (etykieta leku Tetrabenazyna, Przeciwwskazania)

  • TramadolopioidPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Tranylcyprominainhibitor MAOPoważna

    Clinically significant drug interactions with PROVAYBLUE are described below: The concomitant use of PROVAYBLUE with other drugs that affect the serotonergic neurotransmitter system has resulted in serotonin syndrome. (etykieta leku Błękit metylenowy, Interakcje z innymi lekami)

  • Trazodonlek przeciwdepresyjnyPoważna

    Clinically significant drug interactions with PROVAYBLUE are described below: The concomitant use of PROVAYBLUE with other drugs that affect the serotonergic neurotransmitter system has resulted in serotonin syndrome. (etykieta leku Błękit metylenowy, Interakcje z innymi lekami)

  • Trimipraminatrójpierścieniowy lek przeciwdepresyjnyPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Walbenazynainhibitor VMAT2Poważna

    Dose adjustments due to drug interactions ( 2.4 , 7.1 ): Factors Dose Adjustments for INGREZZA and INGREZZA SPRINKLE Use of MAOIs with INGREZZA or INGREZZA SPRINKLE Avoid concomitant use with MAOIs. (etykieta leku Walbenazyna, Interakcje z innymi lekami)

  • WenlafaksynaSNRIPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • WilazodonSSRIPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Wiloksazynainhibitor wychwytu zwrotnego noradrenalinyPoważna

    Avoid concomitant use of PROVAYBLUE with selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), monoamine oxidase inhibitors (MAOIs) and opioids. [see Warnings and Precautions ( 5.1 ) and Drug Interactions ( 7.1 )]. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Wortioksetynalek przeciwdepresyjnyPoważna

    Clinically significant drug interactions with PROVAYBLUE are described below: The concomitant use of PROVAYBLUE with other drugs that affect the serotonergic neurotransmitter system has resulted in serotonin syndrome. (etykieta leku Błękit metylenowy, Interakcje z innymi lekami)

  • ZolmitryptantryptanPoważna

    WARNING: SEROTONIN SYNDROME WITH CONCOMITANT USE OF SEROTONERGIC DRUGS AND OPIOIDS PROVAYBLUE may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. (etykieta leku Błękit metylenowy, Ostrzeżenie w ramce)

  • Zyprazydonlek przeciwpsychotycznyPoważna

    • Concomitant use of monoamine oxidase inhibitors (MAOIs), or use within 14 days of stopping MAOIs. (etykieta leku Zyprazydon, Przeciwwskazania)

Umiarkowane interakcje (59)

  • AdrenalinasympatykomimetykUmiarkowana

    • Drugs that potentiate the effects of epinephrine include sympathomimetics, beta blockers, tricyclic antidepressants, MAO inhibitors, COMT inhibitors, clonidine, doxapram, oxytocin, levothyroxine sodium, and certain antihistamines. (etykieta leku Adrenalina, Interakcje z innymi lekami)

  • Arformoterolagonista receptorów beta-adrenergicznychUmiarkowana

    MAO inhibitors, tricyclic antidepressants and drugs that prolong the QTc interval may potentiate effect on the cardiovascular system. (etykieta leku Arformoterol, Interakcje z innymi lekami)

  • Armodafinillek pobudzający OUNUmiarkowana

    Monoamine Oxidase (MAO) Inhibitors Caution should be used when concomitantly administering MAO inhibitors and NUVIGIL. (etykieta leku Armodafinil, Interakcje z innymi lekami)

  • Artykaina + adrenalinaśrodek znieczulający miejscowoUmiarkowana

    The administration of local anesthetic solutions containing epinephrine to patients receiving monoamine oxidase inhibitors, nonselective beta-adrenergic antagonists, or tricyclic antidepressants may produce severe, prolonged hypertension. (etykieta leku Artykaina + adrenalina, Interakcje z innymi lekami)

  • Brymonidynaagonista receptorów alfa-adrenergicznychUmiarkowana

    Monoamine oxidase inhibitors may result in increased hypotension. (etykieta leku Brymonidyna, Interakcje z innymi lekami)

  • Brymonidyna + tymololagonista receptorów alfa-adrenergicznychUmiarkowana

    Monoamine oxidase inhibitors may result in increased hypotension. (etykieta leku Brymonidyna + tymolol, Interakcje z innymi lekami)

  • Budezonid + formoterolkortykosteroidUmiarkowana

    Monoamine oxidase inhibitors and tricyclic antidepressants: Use with extreme caution. (etykieta leku Budezonid + formoterol, Interakcje z innymi lekami)

  • Bupiwakainaśrodek znieczulający miejscowoUmiarkowana

    …of Adverse Reactions Due to Drug Interactions with MARCAINE WITH EPINEPHRINE Risk of Severe, Persistent Hypertension Due to Drug Interactions Between MARCAINE WITH EPINEPHRINE and Monoamine Oxidase Inhibitors and Tricyclic Antidepressants Administration of MARCAINE WITH EPINEPHRINE (containing a vasoconstrictor) in patients receiving monoamine oxidase inhibitors… (etykieta leku Bupiwakaina, Ostrzeżenia i środki ostrożności)

  • Bupiwakaina + adrenalinaśrodek znieczulający miejscowoUmiarkowana

    …of Adverse Reactions Due to Drug Interactions with MARCAINE WITH EPINEPHRINE Risk of Severe, Persistent Hypertension Due to Drug Interactions Between MARCAINE WITH EPINEPHRINE and Monoamine Oxidase Inhibitors and Tricyclic Antidepressants Administration of MARCAINE WITH EPINEPHRINE (containing a vasoconstrictor) in patients receiving monoamine oxidase inhibitors… (etykieta leku Bupiwakaina + adrenalina, Ostrzeżenia i środki ostrożności)

  • Drug Interactions The CNS effects of butalbital may be enhanced by monoamine oxidase (MAO) inhibitors. (etykieta leku Butalbital + kwas acetylosalicylowy + kofeina, Interakcje z innymi lekami)

  • Butalbital + paracetamolbarbituranUmiarkowana

    Drug Interactions The CNS effects of butalbital may be enhanced by monoamine oxidase (MAO) inhibitors. (etykieta leku Butalbital + paracetamol, Interakcje z innymi lekami)

  • Drug Interactions The CNS effects of butalbital may be enhanced by monoamine oxidase (MAO) inhibitors. (etykieta leku Butalbital + paracetamol + kofeina, Interakcje z innymi lekami)

  • Chloroprokainaśrodek znieczulający miejscowoUmiarkowana

    Drug Interactions The administration of local anesthetic solutions containing epinephrine or norepinephrine to patients receiving monoamine oxidase inhibitors, tricyclic antidepressants or phenothiazines may produce severe, prolonged hypotension or hypertension. (etykieta leku Chloroprokaina, Środki ostrożności)

  • DiazepambenzodiazepinaUmiarkowana

    …be given to the pharmacology of the agents employed particularly with compounds that may potentiate or be potentiated by the action of Valium, such as phenothiazines, antipsychotics, anxiolytics/sedatives, hypnotics, anticonvulsants, narcotic analgesics, anesthetics, sedative antihistamines, narcotics, barbiturates, MAO inhibitors and other antidepressants. (etykieta leku Diazepam, Interakcje z innymi lekami)

  • Dicyklowerynalek przeciwcholinergicznyUmiarkowana

    …drugs including dicyclomine hydrochloride: amantadine, antiarrhythmic agents of Class I (e.g., quinidine), antihistamines, antipsychotic agents (e.g., phenothiazines), benzodiazepines, MAO inhibitors, narcotic analgesics (e.g., meperidine), nitrates and nitrites, sympathomimetic agents, tricyclic antidepressants, and other drugs having anticholinergic activity. (etykieta leku Dicykloweryna, Interakcje z innymi lekami)

  • Difenhydraminalek przeciwhistaminowyUmiarkowana

    MAO inhibitors prolong and intensify the anticholinergic (drying) effects of antihistamines. (etykieta leku Difenhydramina, Interakcje z innymi lekami)

  • Droperydolantagonista dopaminyUmiarkowana

    …1) clinically significant bradycardia (less than 50 bpm), 2) any clinically significant cardiac disease, 3) treatment with Class I and Class III antiarrhythmics, 4) treatment with monoamine oxidase inhibitors (MAOI's), 5) concomitant treatment with other drug products known to prolong the QT interval (see PRECAUTIONS, Drug Interactions ), and 6) electrolyte imbalance,… (etykieta leku Droperydol, Ostrzeżenia)

  • EstazolambenzodiazepinaUmiarkowana

    The action of the benzodiazepines may be potentiated by anticonvulsants, antihistamines, alcohol, barbiturates, monoamine oxidase inhibitors, narcotics, phenothiazines, psychotropic medications, or other drugs that produce CNS depression. (etykieta leku Estazolam, Interakcje z innymi lekami)

  • Fenylefrynalek obkurczający błonę śluzową nosaUmiarkowana

    Agonistic Effects (increase in BIORPHEN blood pressure effect) can occur with monoamine oxidase inhibitors (MAOI), oxytocin and oxytocic drugs, tricyclic antidepressants, angiotensin and aldosterone, atropine, steroids, norepinephrine transporter inhibitors, ergot alkaloids. (etykieta leku Fenylefryna, Interakcje z innymi lekami)

  • Flutykazon + salmeterolkortykosteroidUmiarkowana

    Monoamine oxidase inhibitors and tricyclic antidepressants: Use with extreme caution. (etykieta leku Flutykazon + salmeterol, Interakcje z innymi lekami)

  • Formoterolagonista receptorów beta-adrenergicznychUmiarkowana

    • MAO inhibitors, tricyclic antidepressants and drugs that prolong QTc interval may potentiate effect on the cardiovascular system. (etykieta leku Formoterol, Interakcje z innymi lekami)

  • Glibenklamidpochodna sulfonylomocznikaUmiarkowana

    …Interactions The hypoglycemic action of sulfonylureas may be potentiated by certain drugs including nonsteroidal anti-inflammatory agents, ACE inhibitors, disopyramide, fluoxetine, clarithromycin, and other drugs that are highly protein bound, salicylates, sulfonamides, chloramphenicol, probenecid, monoamine oxidase inhibitors, and beta adrenergic blocking agents. (etykieta leku Glibenklamid, Interakcje z innymi lekami)

  • Glimepirydpochodna sulfonylomocznikaUmiarkowana

    …steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides, chloramphenicol, coumarins, probenecid and monoamine oxidase inhibitors. (etykieta leku Glimepiryd, Interakcje z innymi lekami)

  • Glipizydpochodna sulfonylomocznikaUmiarkowana

    …increase the susceptibility to and/or intensity of hypoglycemia: antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, propoxyphene, salicylates, somatostatin analogs (e.g., octreotide), sulfonamide antibiotics, nonsteroidal anti-inflammatory… (etykieta leku Glipizyd, Interakcje z innymi lekami)

  • Glipizyd + metforminapochodna sulfonylomocznikaUmiarkowana

    Glipizide: The hypoglycemic action of sulfonylureas may be potentiated by certain drugs, including nonsteroidal anti-inflammatory agents, some azoles, and other drugs that are highly protein bound, salicylates, sulfonamides, chloramphenicol, probenecid, coumarins, monoamine oxidase inhibitors, and beta-adrenergic blocking agents. (etykieta leku Glipizyd + metformina, Środki ostrożności)

  • Hydralazynalek rozszerzający naczyniaUmiarkowana

    Drug Interactions MAO inhibitors should be used with caution in patients receiving hydralazine. (etykieta leku Hydralazyna, Interakcje z innymi lekami)

  • IfosfamidUmiarkowana

    Consider methylene blue for treatment of encephalopathy. (etykieta leku Ifosfamid, Ostrzeżenia i środki ostrożności)

  • Insulina aspartinsulinaUmiarkowana

    Drugs That May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analog (e.g., octreotide), and sulfonamide antibiotics. (etykieta leku Insulina aspart, Interakcje z innymi lekami)

  • Insulina degludecinsulinaUmiarkowana

    …Degludec Drugs That May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics, GLP-1 receptor agonists, DPP-4 inhibitors,… (etykieta leku Insulina degludec, Interakcje z innymi lekami)

  • Insulina detemirinsulinaUmiarkowana

    …with LEVEMIR Drugs That May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics, GLP-1 receptor agonists, DPP-4 inhibitors,… (etykieta leku Insulina detemir, Interakcje z innymi lekami)

  • Insulina glargineinsulinaUmiarkowana

    …Glargine-yfgn Drugs that May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), sulfonamide antibiotics, GLP-1 receptor agonists, DPP-4 inhibitors,… (etykieta leku Insulina glargine, Interakcje z innymi lekami)

  • Insulina lisproinsulinaUmiarkowana

    Clinically Significant Drug Interactions with LYUMJEV Drugs That May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics. (etykieta leku Insulina lispro, Interakcje z innymi lekami)

  • …Significant Drug Interactions with AFREZZA Antidiabetic agents, Angiotensin-Converting Enzyme Inhibitors, Angiotensin II Receptor Blocking Agents, Disopyramide, Fibrates, Fluoxetine, Monoamine Oxidase Inhibitors, Pentoxifylline, Pramlintide, Salicylates, Somatostatin Analogs (e.g., octreotide), and Sulfonamide Antibiotics Prevention or Management Monitor blood glucose… (etykieta leku Insulina ludzka krótko działająca, Interakcje z innymi lekami)

  • Ipratropium + salbutamollek przeciwcholinergicznyUmiarkowana

    Monoamine Oxidase Inhibitors or Tricyclic Antidepressants Ipratropium Bromide and Albuterol Sulfate Inhalation Solution should be administered with extreme caution to patients being treated with monoamine oxidase inhibitors or tricyclic antidepressants, or within 2 weeks of discontinuation of such agents because the action of albuterol sulfate on the cardiovascular… (etykieta leku Ipratropium + salbutamol, Interakcje z innymi lekami)

  • Izofluranśrodek do znieczulenia ogólnegoUmiarkowana

    Concomitant Use with MAO Inhibitors Concomitant use of MAO inhibitors and inhalational anesthetics may increase the risk of hemodynamic instability during surgery or medical procedures. (etykieta leku Izofluran, Interakcje z innymi lekami)

  • Izoprenalinaagonista receptorów beta-adrenergicznychUmiarkowana

    Drugs that may potentiate clinical response of Isoproterenol Clinical Impact The effects of isoproterenol may be potentiated by tricyclic antidepressants, monoamine oxidase inhibitors, levothyroxine sodium, and certain antihistamines, notably chlorpheniramine, tripelennamine, and diphenhydramine. (etykieta leku Izoprenalina, Interakcje z innymi lekami)

  • Karwedilolbeta-blokerUmiarkowana

    Hypotensive agents (e.g., reserpine, MAO inhibitors, clonidine) may increase the risk of hypotension and/or severe bradycardia. (etykieta leku Karwedilol, Interakcje z innymi lekami)

  • Klemastynalek przeciwhistaminowyUmiarkowana

    Monoamine oxidase (MAO) inhibitors prolong and intensify the anticholinergic effects of antihistamines. (etykieta leku Klemastyna, Interakcje z innymi lekami)

  • KlonazepambenzodiazepinaUmiarkowana

    …Interactions The CNS-depressant action of the benzodiazepine class of drugs may be potentiated by alcohol, narcotics, barbiturates, nonbarbiturate hypnotics, antianxiety agents, the phenothiazines, thioxanthene and butyrophenone classes of antipsychotic agents, monoamine oxidase inhibitors and the tricyclic antidepressants, and by other anticonvulsant drugs. (etykieta leku Klonazepam, Interakcje z innymi lekami)

  • KlorazepanbenzodiazepinaUmiarkowana

    The actions of the benzodiazepines may be potentiated by barbiturates, narcotics, phenothiazines, monoamine oxidase inhibitors or other antidepressants. (etykieta leku Klorazepan, Interakcje z innymi lekami)

  • Kokainaśrodek znieczulający miejscowoUmiarkowana

    Monoamine-oxidase inhibitors: Concomitant administration may potentiate the effects and toxicity of monoamine-oxidase inhibitors. (etykieta leku Kokaina, Interakcje z innymi lekami)

  • Lewosalbutamolagonista receptorów beta-adrenergicznychUmiarkowana

    Monoamine oxidase inhibitors (MAOs) or tricyclic antidepressants : May potentiate effect of albuterol on the cardiovascular system. (etykieta leku Lewosalbutamol, Interakcje z innymi lekami)

  • Lidokainaśrodek znieczulający miejscowoUmiarkowana

    Clinically Significant Drug Interactions The administration of local anesthetic solutions containing epinephrine or norepinephrine to patients receiving monoamine oxidase inhibitors or tricyclic antidepressants may produce severe, prolonged hypertension. (etykieta leku Lidokaina, Interakcje z innymi lekami)

  • Lidokaina + adrenalinaśrodek znieczulający miejscowoUmiarkowana

    Risk of Adverse Reactions Due to Drug Interactions with FLAVALTA Risk of Severe, Persistent Hypertension Due to Drug Interactions Between FLAVALTA and Monoamine Oxidase Inhibitors and Tricyclic Antidepressants Administration of FLAVALTA (containing a vasoconstrictor, epinephrine) in patients receiving monoamine oxidase inhibitors (MAOI), or tricyclic antidepressants… (etykieta leku Lidokaina + adrenalina, Ostrzeżenia i środki ostrożności)

  • Mepiwakainaśrodek znieczulający miejscowoUmiarkowana

    Likewise, solutions of mepivacaine containing a vasoconstrictor, such as epinephrine, should be used with extreme caution in patients receiving monoamine oxidase inhibitors (MAOI) or antidepressants of the triptyline or imipramine types, because severe prolonged hypertension may result. (etykieta leku Mepiwakaina, Ostrzeżenia)

  • Metoprololbeta-blokerUmiarkowana

    Catecholamine depleting drugs (e.g., reserpine, monoamine oxidase (MAO) inhibitors) may have an additive effect when given with beta-blocking agents. (etykieta leku Metoprolol, Interakcje z innymi lekami)

  • Metoprolol + hydrochlorotiazydbeta-blokerUmiarkowana

    Catecholamine-depleting drugs (e.g., MAO inhibitors): Hypotension, bradycardia. (etykieta leku Metoprolol + hydrochlorotiazyd, Interakcje z innymi lekami)

  • Modafinillek pobudzający OUNUmiarkowana

    Monoamine Oxidase (MAO) Inhibitors Caution should be used when concomitantly administering MAO inhibitors and PROVIGIL. (etykieta leku Modafinil, Interakcje z innymi lekami)

  • NateglinidmeglitynidUmiarkowana

    …Nateglinide Drugs That May Increase the Blood-Glucose-Lowering Effect of Nateglinide and Susceptibility to Hypoglycemia Drugs: Nonsteroidal anti-inflammatory drugs (NSAIDs), salicylates, monoamine oxidase inhibitors, non-selective beta-adrenergic-blocking agents, anabolic hormones (e.g., methandrostenolone), guanethidine, gymnema sylvestre, glucomannan, thioctic acid,… (etykieta leku Nateglinid, Interakcje z innymi lekami)

  • Oksymetazolinalek obkurczający błonę śluzową nosaUmiarkowana

    Monoamine Oxidase Inhibitors Caution is advised in patients taking MAO inhibitors which can affect the metabolism and uptake of circulating amines. (etykieta leku Oksymetazolina, Interakcje z innymi lekami)

  • Pioglitazon + glimepirydtiazolidynodionUmiarkowana

    …steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides, chloramphenicol, coumarins, probenecid and monoamine oxidase inhibitors. (etykieta leku Pioglitazon + glimepiryd, Interakcje z innymi lekami)

  • Prometazynalek przeciwhistaminowyUmiarkowana

    Monoamine Oxidase Inhibitors (MAOI) Drug interactions, including an increased incidence of extrapyramidal effects, have been reported when some MAOI and phenothiazines are used concomitantly. (etykieta leku Prometazyna, Interakcje z innymi lekami)

  • Prylokaina + adrenalinaśrodek znieczulający miejscowoUmiarkowana

    …Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine The administration of local anesthetic injections containing epinephrine or norepinephrine to patients receiving monoamine oxidase inhibitors, tricyclic antidepressants or phenothiazines may produce severe, prolonged hypotension or hypertension. (etykieta leku Prylokaina + adrenalina, Interakcje z innymi lekami)

  • Salbutamolagonista receptorów beta-adrenergicznychUmiarkowana

    Monoamine oxidase inhibitors and tricyclic antidepressants: Use with extreme caution. (etykieta leku Salbutamol, Interakcje z innymi lekami)

  • Salmeterolagonista receptorów beta-adrenergicznychUmiarkowana

    • Monoamine oxidase inhibitors and tricyclic antidepressants: Use with extreme caution. (etykieta leku Salmeterol, Interakcje z innymi lekami)

  • Sewofluranśrodek do znieczulenia ogólnegoUmiarkowana

    Non-selective MAO-inhibitors Concomitant use of MAO inhibitors and inhalational anesthetics may increase the risk of hemodynamic instability during surgery or medical procedures. (etykieta leku Sewofluran, Interakcje z innymi lekami)

  • Suksametoniumlek blokujący przewodnictwo nerwowo-mięśnioweUmiarkowana

    The neuromuscular blocking effect of succinylcholine may be enhanced by drugs that reduce plasma cholinesterase activity (e.g., chronically administered oral contraceptives, glucocorticoids, or certain monoamine oxidase inhibitors) or by drugs that irreversibly inhibit plasma cholinesterase [see Warnings and Precautions (5.9) ]. (etykieta leku Suksametonium, Interakcje z innymi lekami)

  • Terbutalinaagonista receptorów beta-adrenergicznychUmiarkowana

    Monoamine Oxidase Inhibitors and Tricyclic Antidepressants Terbutaline sulfate should be administered with extreme caution to patients being treated with monoamine oxidase inhibitors or tricyclic antidepressants, or within 2 weeks of discontinuation of such agents, since the action of terbutaline sulfate on the vascular system may be potentiated. (etykieta leku Terbutalina, Środki ostrożności)

  • Umeklidynium + wilanterollek przeciwcholinergicznyUmiarkowana

    • Monoamine oxidase inhibitors and tricyclic antidepressants: Use with extreme caution. (etykieta leku Umeklidynium + wilanterol, Interakcje z innymi lekami)

Wzmianki o niewielkim znaczeniu (23)

  • Acetazolamidinhibitor anhydrazy węglanowejNiewielka

    Lack of Effectiveness Methemoglobinemia may not resolve or may rebound after response to treatment with PROVAYBLUE in patients with methemoglobinemia due to aryl amines such as aniline or sulfa drugs such as dapsone. (etykieta leku Błękit metylenowy, Ostrzeżenia i środki ostrożności)

  • Brynzolamidinhibitor anhydrazy węglanowejNiewielka

    Lack of Effectiveness Methemoglobinemia may not resolve or may rebound after response to treatment with PROVAYBLUE in patients with methemoglobinemia due to aryl amines such as aniline or sulfa drugs such as dapsone. (etykieta leku Błękit metylenowy, Ostrzeżenia i środki ostrożności)

  • DapsonNiewielka

    Lack of Effectiveness Methemoglobinemia may not resolve or may rebound after response to treatment with PROVAYBLUE in patients with methemoglobinemia due to aryl amines such as aniline or sulfa drugs such as dapsone. (etykieta leku Błękit metylenowy, Ostrzeżenia i środki ostrożności)

  • Drug Interactions Since the chemical structure of difenoxin hydrochloride is similar to meperidine hydrochloride, the concurrent use of MOTOFEN ® with monoamine oxidase inhibitors may, in theory, precipitate a hypertensive crisis. (etykieta leku Difenoksyna + atropina, Interakcje z innymi lekami)

  • Diklofenamidinhibitor anhydrazy węglanowejNiewielka

    Lack of Effectiveness Methemoglobinemia may not resolve or may rebound after response to treatment with PROVAYBLUE in patients with methemoglobinemia due to aryl amines such as aniline or sulfa drugs such as dapsone. (etykieta leku Błękit metylenowy, Ostrzeżenia i środki ostrożności)

  • Dorzolamidinhibitor anhydrazy węglanowejNiewielka

    Lack of Effectiveness Methemoglobinemia may not resolve or may rebound after response to treatment with PROVAYBLUE in patients with methemoglobinemia due to aryl amines such as aniline or sulfa drugs such as dapsone. (etykieta leku Błękit metylenowy, Ostrzeżenia i środki ostrożności)

  • Dorzolamid + tymololinhibitor anhydrazy węglanowejNiewielka

    Lack of Effectiveness Methemoglobinemia may not resolve or may rebound after response to treatment with PROVAYBLUE in patients with methemoglobinemia due to aryl amines such as aniline or sulfa drugs such as dapsone. (etykieta leku Błękit metylenowy, Ostrzeżenia i środki ostrożności)

  • EfedrynasympatykomimetykNiewielka

    Clonidine, propofol, monoamine oxidase inhibitors (MAOIs), atropine C linical Impact: These drugs augment the pressor effect of ephedrine. (etykieta leku Efedryna, Interakcje z innymi lekami)

  • EntakaponNiewielka

    It is theoretically possible, therefore, that the combination of Entacapone Tablets and a non-selective MAO inhibitor (e.g., phenelzine and tranylcypromine) would result in inhibition of the majority of the pathways responsible for normal catecholamine metabolism. (etykieta leku Entakapon, Ostrzeżenia)

  • Glibenklamid + metforminapochodna sulfonylomocznikaNiewielka

    Examples: Nonsteroidal anti-inflammatory agents and other highly protein-boind drugs, salicylcates, sulfonamides, chloramphenicol, probenecid, coumarins, monoamine oxidase inhibitors, beta-adrenergic blocking agents; potentially with ciprofloxacin, micronazole. (etykieta leku Glibenklamid + metformina, Interakcje z innymi lekami)

  • Lidokaina + prylokainaśrodek znieczulający miejscowoNiewielka

    A more severe clinical presentation may require treatment with methylene blue, exchange transfusion, or hyperbaric oxygen. (etykieta leku Lidokaina + prylokaina, Ostrzeżenia i środki ostrożności)

  • Metazolamidinhibitor anhydrazy węglanowejNiewielka

    Lack of Effectiveness Methemoglobinemia may not resolve or may rebound after response to treatment with PROVAYBLUE in patients with methemoglobinemia due to aryl amines such as aniline or sulfa drugs such as dapsone. (etykieta leku Błękit metylenowy, Ostrzeżenia i środki ostrożności)

  • Propranololbeta-blokerNiewielka

    Antidepressants: The hypotensive effect of MAO inhibitors or tricyclic antidepressants may be exacerbated when administered with beta-blockers. (etykieta leku Propranolol, Interakcje z innymi lekami)

  • RepaglinidmeglitynidNiewielka

    Examples: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, nonsteroidal anti-inflammatory agents (NSAIDs), pentoxifylline, pramlintide, propoxyphene, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics. (etykieta leku Repaglinid, Interakcje z innymi lekami)

  • Ropiwakainaśrodek znieczulający miejscowoNiewielka

    A more severe clinical presentation may require treatment with methylene blue, exchange transfusion, or hyperbaric oxygen. (etykieta leku Ropiwakaina, Ostrzeżenia i środki ostrożności)

  • SulfadiazynasulfonamidNiewielka

    Lack of Effectiveness Methemoglobinemia may not resolve or may rebound after response to treatment with PROVAYBLUE in patients with methemoglobinemia due to aryl amines such as aniline or sulfa drugs such as dapsone. (etykieta leku Błękit metylenowy, Ostrzeżenia i środki ostrożności)

  • Sulfadiazyna srebrowasulfonamidNiewielka

    Lack of Effectiveness Methemoglobinemia may not resolve or may rebound after response to treatment with PROVAYBLUE in patients with methemoglobinemia due to aryl amines such as aniline or sulfa drugs such as dapsone. (etykieta leku Błękit metylenowy, Ostrzeżenia i środki ostrożności)

  • Lack of Effectiveness Methemoglobinemia may not resolve or may rebound after response to treatment with PROVAYBLUE in patients with methemoglobinemia due to aryl amines such as aniline or sulfa drugs such as dapsone. (etykieta leku Błękit metylenowy, Ostrzeżenia i środki ostrożności)

  • SulfasalazynasulfonamidNiewielka

    Lack of Effectiveness Methemoglobinemia may not resolve or may rebound after response to treatment with PROVAYBLUE in patients with methemoglobinemia due to aryl amines such as aniline or sulfa drugs such as dapsone. (etykieta leku Błękit metylenowy, Ostrzeżenia i środki ostrożności)

  • Terbinafinalek przeciwgrzybiczyNiewielka

    Drugs predominantly metabolized by the CYP450 2D6 isozyme include the following drug classes: tricyclic antidepressants, selective serotonin reuptake inhibitors, beta-blockers, antiarrhythmics class 1C (e.g., flecainide and propafenone) and monoamine oxidase inhibitors Type B. (etykieta leku Terbinafina, Interakcje z innymi lekami)

  • TolkaponNiewielka

    It is theoretically possible, therefore, that the combination of Tolcapone tablets and a non-selective MAO inhibitor (e.g., phenelzine and tranylcypromine) would result in inhibition of the majority of the pathways responsible for normal catecholamine metabolism. (etykieta leku Tolkapon, Ostrzeżenia)

  • Triheksyfenidyllek przeciwcholinergicznyNiewielka

    Monoamine oxidase inhibitors and tricyclic antidepressants possessing significant anticholinergic activity may intensify the anticholinergic effects of antidyskinetic agents because of the secondary anticholinergic activities of these medications. (etykieta leku Triheksyfenidyl, Interakcje z innymi lekami)

  • Zonisamidlek przeciwdrgawkowyNiewielka

    Lack of Effectiveness Methemoglobinemia may not resolve or may rebound after response to treatment with PROVAYBLUE in patients with methemoglobinemia due to aryl amines such as aniline or sulfa drugs such as dapsone. (etykieta leku Błękit metylenowy, Ostrzeżenia i środki ostrożności)

Sprawdź, jak Błękit metylenowy łączy się ze wszystkim, co przyjmujesz. Dodaj całą listę; wszystkie pary są sprawdzane jednocześnie.

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To nie jest porada medyczna. Stopień nasilenia odzwierciedla sformułowania etykiety, a nie indywidualne okoliczności. Oznaczenie „poważna” może dotyczyć połączenia stosowanego rutynowo pod nadzorem, a „niewielka” może mieć znaczenie przy dużych dawkach. Należy zapytać farmaceutę.