Prednizolon: interakcje
Prednizolon (Orapred, Millipred, Pediapred), kortykosteroid: 400 udokumentowanych interakcji w indeksowanych przez nas etykietach FDA i kartach informacyjnych. Poważne: 29, umiarkowane: 288, niewielkie: 82, pary, dla których etykieta nie zgłasza istotnej interakcji: 1. Każda pozycja poniżej cytuje zdanie, na którym się opiera. Ta strona leku to punkt wyjścia, a nie rozstrzygnięcie dla indywidualnej sytuacji.
Interakcje z etykiety
Poważne interakcje (29)
At the primary analysis, increased incidences of fractures (28.6% vs 11.4%) and deaths (38.5% vs 35.5%) have been observed in patients who received abiraterone acetate plus a corticosteroid in combination with radium Ra 223 dichloride compared to patients who received placebo in combination with abiraterone acetate plus a corticosteroid. (etykieta leku Abirateron, Ostrzeżenia i środki ostrożności)
Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (etykieta leku Adalimumab, Ostrzeżenie w ramce)
…Antihistamines Thyroid hormones Diuretics Cardiac glycosides, such as digitalis glycosides Quinidine Drugs potentiating hypokalemic effects of epinephrine • Potassium depleting diuretics • Corticosteroids • Theophylline Epinephrine should not be used to counteract circulatory collapse or hypotension caused by phenothiazines, as a reversal of the pressor effects of epinephrine… (etykieta leku Adrenalina, Interakcje z innymi lekami)
- AksytynibPoważna
Withhold INLYTA and avelumab or pembrolizumab, initiate corticosteroid therapy as needed, and/or permanently discontinue the combination for severe or life-threatening hepatotoxicity. (etykieta leku Aksytynib, Ostrzeżenia i środki ostrożności)
Use of a LABA, including arformoterol tartrate inhalation solution, without an inhaled corticosteroid is contraindicated in patients with asthma. (etykieta leku Arformoterol, Przeciwwskazania)
Most patients with rheumatoid arthritis who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (etykieta leku Baricytynib, Ostrzeżenie w ramce)
- DocetakselPoważna
Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (etykieta leku Docetaksel, Ostrzeżenia i środki ostrożności)
…(5.7) , Drug Interactions (7) , and Clinical Pharmacology (12.3) ]: Anticonvulsants: carbamazepine, oxcarbazepine, phenobarbital, phenytoin Antimycobacterials: rifampin, rifapentine Glucocorticoid (systemic): dexamethasone (more than a single-dose) Herbal Products: St John's wort ( Hypericum perforatum ) Proton Pump Inhibitors: e.g., dexlansoprazole, esomeprazole,… (etykieta leku Emtrycytabina + rylpiwiryna + tenofowir, Przeciwwskazania)
Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (etykieta leku Etanercept, Ostrzeżenie w ramce)
Use of a LABA, including formoterol fumarate inhalation solution, without an inhaled corticosteroid is contraindicated in patients with asthma [see Warnings and Precautions (5.1) ]. (etykieta leku Formoterol, Przeciwwskazania)
Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (etykieta leku Infliksymab, Ostrzeżenie w ramce)
Fluticasone: Coadministration of fluticasone propionate and ketoconazole is not recommended unless the potential benefit to the patient outweighs the risk of systemic corticosteroid side effects. (etykieta leku Ketokonazol, Interakcje z innymi lekami)
Moreover, cholesterol and other products of the cholesterol biosynthesis pathway are essential components for fetal development, including synthesis of steroids and cell membranes. (etykieta leku Lowastatyna, Przeciwwskazania)
WARNING: TERMINATION OF PREGNANCY Mifepristone is a potent antagonist of progesterone and cortisol via the progesterone and glucocorticoid (GR-II) receptors, respectively. (etykieta leku Mifepryston, Ostrzeżenie w ramce)
If shock, severe trauma or infection occurs or develops, temporarily discontinue LYSODREN and administer exogenous steroids. (etykieta leku Mitotan, Ostrzeżenie w ramce)
None of the cases were considered life-threatening and all resolved either without treatment or with medication (antihistamines or glucocorticoids). (etykieta leku Moeksypryl, Ostrzeżenia)
Antimycobacterials Rifampin Rifapentine Glucocorticoid (systemic) Dexamethasone (more than a single-dose treatment) Herbal Products St. (etykieta leku Rylpiwiryna, Przeciwwskazania)
WARNING: ASTHMA-RELATED DEATH Long-acting beta 2 -adrenergic agonists (LABA), such as salmeterol, the active ingredient in SEREVENT DISKUS, as monotherapy (without inhaled corticosteroids [ICS]) increase the risk of asthma-related death. (etykieta leku Salmeterol, Ostrzeżenie w ramce)
- SomatropinaPoważna
Intervention: Carefully adjust glucocorticoid dosing in pediatric patients receiving glucocorticoid treatments to avoid both hypoadrenalism and an inhibitory effect on growth. (etykieta leku Somatropina, Interakcje z innymi lekami)
In a multicenter clinical study, de novo renal transplant patients treated with sirolimus, mycophenolate mofetil (MMF), steroids, and an IL-2 receptor antagonist had significantly higher acute rejection rates and numerically higher death rates compared to patients treated with cyclosporine, MMF, steroids, and IL-2 receptor antagonist. (etykieta leku Syrolimus, Ostrzeżenia i środki ostrożności)
Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (etykieta leku Tocilizumab, Ostrzeżenie w ramce)
Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (etykieta leku Tofacytynib, Ostrzeżenie w ramce)
Two of the four cases were life-threatening and resolved without treatment or with medication (corticosteroids). (etykieta leku Trandolapryl, Ostrzeżenia)
At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (etykieta leku Tretynoina, Ostrzeżenie w ramce)
If differentiation syndrome is suspected, immediately initiate high-dose corticosteroids and hemodynamic monitoring until resolution. (etykieta leku Trójtlenek arsenu, Ostrzeżenie w ramce)
• use of a long-acting beta 2 -adrenergic agonist (LABA), including vilanterol, one of the active ingredients in Umeclidinium and Vilanterol ELLIPTA, without an inhaled corticosteroid (ICS), in patients with asthma [see Warnings and Precautions ( 5.1 )] . (etykieta leku Umeklidynium + wilanterol, Przeciwwskazania)
Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (etykieta leku Upadacytynib, Ostrzeżenie w ramce)
Umiarkowane interakcje (288)
- AfatynibUmiarkowana
Patients receiving concomitant corticosteroids, nonsteroidal anti-inflammatory drugs (NSAIDs) or anti-angiogenic agents, or patients with increasing age or who have an underlying history of gastrointestinal ulceration, underlying diverticular disease or bowel metastases may be at increased risk of perforation. (etykieta leku Afatynib, Ostrzeżenia i środki ostrożności)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Sympathomimetics, Methylxanthines, Steroids In clinical studies, concurrent administration of aclidinium bromide and other drugs commonly used in the treatment of COPD including sympathomimetics (short-acting beta 2 agonists), methylxanthines, and oral and inhaled steroids showed no increases in adverse drug reactions. (etykieta leku Aklidynium, Interakcje z innymi lekami)
- AlbendazolUmiarkowana
Risk of Neurologic Symptoms: Neurocysticercosis patients may experience cerebral hypertensive episodes, seizures or focal neurologic deficits after initiation of therapy; begin appropriate steroid and anticonvulsant therapy. (etykieta leku Albendazol, Ostrzeżenia i środki ostrożności)
Institute appropriate medical management (e.g., glucocorticoids, epinephrine, meperidine) for infusion-related reactions as needed [see Dosage and Administration (2.2) ] . (etykieta leku Alemtuzumab, Ostrzeżenia i środki ostrożności)
Patients who experience these effects, even without respiratory distress, require prolonged observation and appropriate monitoring measures since treatment with antihistamines and corticosteroids may not be sufficient to prevent respiratory involvement. (etykieta leku Aliskiren, Ostrzeżenia i środki ostrożności)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
- AlpelisybUmiarkowana
If a SCAR is not confirmed, VIJOICE may require dose modifications, topical or systemic corticosteroids, or oral antihistamine treatment as described in Table 4 [see Dosage and Administration (2.5)] . (etykieta leku Alpelisyb, Ostrzeżenia i środki ostrożności)
Corticosteroids and Corticotropin (ACTH) Concurrent use of corticosteroids and ACTH may potentiate hypokalemia, which could predispose the patient to cardiac dysfunction. (etykieta leku Amfoterycyna B, Interakcje z innymi lekami)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Lung function (FEV 1 or PEF), beta‑agonist use, and asthma symptoms should be carefully monitored during withdrawal of oral or other systemic corticosteroids. (etykieta leku Beklometazon, Ostrzeżenia i środki ostrożności)
- BendamustynaUmiarkowana
Consider measures to prevent severe reactions, including antihistamines, antipyretics and corticosteroids in subsequent cycles in patients who have experienced Grade 1 or 2 infusion reactions. (etykieta leku Bendamustyna, Ostrzeżenia i środki ostrożności)
- BenralizumabUmiarkowana
• Reduction in Corticosteroid Dosage: Do not discontinue systemic or inhaled corticosteroids abruptly upon initiation of therapy with FASENRA. (etykieta leku Benralizumab, Ostrzeżenia i środki ostrożności)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Corticosteroids (systemic): cortisone/hydrocortisone dexamethasone ↑ corticosteroids (systemic) ↓ lenacapavir (dexamethasone) Concomitant administration with systemic corticosteroids whose exposures are significantly increased by CYP3A inhibitors can increase the risk for Cushing's syndrome and adrenal suppression. (etykieta leku Biktegrawir + emtrycytabina + alafenamid tenofowiru, Interakcje z innymi lekami)
Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
In this situation, the patient requires immediate re-evaluation with reassessment of the treatment regimen, giving special consideration to the possible need for replacing the current strength of budesonide and formoterol fumarate dihydrate with a higher strength, adding additional inhaled corticosteroid, or initiating systemic corticosteroids. (etykieta leku Budezonid + formoterol, Ostrzeżenia i środki ostrożności)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Buprenorfina, Ostrzeżenia i środki ostrożności)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Buprenorfina + nalokson, Ostrzeżenia i środki ostrożności)
…risk of seizure: concomitant use of other medications that lower the seizure threshold (e.g., other bupropion products, antipsychotics, tricyclic antidepressants, theophylline, and systemic corticosteroids), metabolic disorders (e.g., hypoglycemia, hyponatremia, severe hepatic impairment, and hypoxia), or use of illicit drugs (e.g., cocaine) or abuse or misuse… (etykieta leku Bupropion, Ostrzeżenia i środki ostrożności)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Butorfanol, Ostrzeżenia)
High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (etykieta leku Cefoksytyna, Ostrzeżenia i środki ostrożności)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Cyclosporine: Increased activity of both cyclosporine and corticosteroids may occur when the two are used concurrently. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
The risk of developing fluoroquinolone-associated tendinitis and tendon rupture is increased in patients over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. (etykieta leku Cyprofloksacyna, Ostrzeżenia i środki ostrożności)
These reactions include reversible corneal toxicity, and hemorrhagic conjunctivitis, which may be prevented or diminished by prophylaxis with a local corticosteroid eye drop; cerebral and cerebellar dysfunction, including personality changes, somnolence and coma, usually reversible; severe gastrointestinal ulceration, including pneumatosis cystoides intestinalis… (etykieta leku Cytarabina, Ostrzeżenia)
Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (etykieta leku Daptomycyna, Ostrzeżenia i środki ostrożności)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
- DenosumabUmiarkowana
Other risk factors for the development of ONJ include immunosuppressive therapy, treatment with angiogenesis inhibitors, systemic corticosteroids, diabetes, and gingival infections. (etykieta leku Denosumab, Ostrzeżenia i środki ostrożności)
Estrogens, including oral contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids thereby increasing their effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Anticholinergic drugs in the presence of increased intraocular pressure may be hazardous when taken concurrently with agents such as corticosteroids. (etykieta leku Dicykloweryna, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Digitalis: Patients on digitalis glycosides may be at increased risk of arrhythmias due to hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Estrogens, including oral contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids thereby increasing their effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Estrogens, including oral contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids thereby increasing their effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
- DupilumabUmiarkowana
Eosinophilic Conditions: Be alert to vasculitic rash, worsening pulmonary symptoms, cardiac complications, kidney injury and/or neuropathy, especially upon reduction of oral corticosteroids. (etykieta leku Dupilumab, Ostrzeżenia i środki ostrożności)
Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
- Eleksakaftor + tezakaftor + iwakaftorUmiarkowana
Although other risk factors were present in some cases (such as corticosteroid use, exposure to radiation), a possible risk attributable to treatment with ivacaftor cannot be excluded. (etykieta leku Eleksakaftor + tezakaftor + iwakaftor, Ostrzeżenia i środki ostrożności)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
- ErlotynibUmiarkowana
Patients receiving concomitant anti-angiogenic agents, corticosteroids, NSAIDs, or taxane-based chemotherapy, or who have prior history of peptic ulceration or diverticular disease may be at increased risk of perforation [see Adverse Reactions (6.1 , 6.2) ]. (etykieta leku Erlotynib, Ostrzeżenia i środki ostrożności)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Estrogens, including oral contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids thereby increasing their effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Estrogens, including oral contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids thereby increasing their effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Estrogens, including oral contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids thereby increasing their effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Estrogens, including oral contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids thereby increasing their effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Estrogens, including oral contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids thereby increasing their effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Estrogens, including oral contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids thereby increasing their effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Estrogens, including oral contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids thereby increasing their effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Fentanyl, Ostrzeżenia i środki ostrożności)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Agonistic Effects (increase in BIORPHEN blood pressure effect) can occur with monoamine oxidase inhibitors (MAOI), oxytocin and oxytocic drugs, tricyclic antidepressants, angiotensin and aldosterone, atropine, steroids, norepinephrine transporter inhibitors, ergot alkaloids. (etykieta leku Fenylefryna, Interakcje z innymi lekami)
- Fenylomaślan gliceroluUmiarkowana
Corticosteroids, valproic acid, or haloperidol : May increase plasma ammonia level; monitor ammonia levels closely. (etykieta leku Fenylomaślan glicerolu, Interakcje z innymi lekami)
- Fenylomaślan soduUmiarkowana
Valproic Acid, Haloperidol, or Corticosteroids : May increase plasma ammonia level; monitor ammonia levels closely. (etykieta leku Fenylomaślan sodu, Interakcje z innymi lekami)
- Fenylooctan sodu + benzoesan soduUmiarkowana
Use of corticosteroids may cause a protein catabolic state and, thereby, potentially increase plasma ammonia levels in patients with impaired ability to form urea. (etykieta leku Fenylooctan sodu + benzoesan sodu, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
In both cases, the patients were taking a 1.25 mg dose of fingolimod (higher than the recommended 0.5 mg dose) and had received high-dose corticosteroid therapy to treat suspected MS relapses. (etykieta leku Fingolimod, Ostrzeżenia i środki ostrożności)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Pregnancy As with other corticosteroids, flunisolide has been shown to be teratogenic and fetotoxic in rabbits and rats at oral doses of 40 and 200 mcg/kg/day, respectively (approximately 2 and 4 times, respectively, the maximum recommended daily intranasal dose in adults on a mg/m 2 basis). (etykieta leku Flunizolid, Środki ostrożności)
Use of more than one corticosteroid-containing product at the same time may increase the total systemic absorption of topical corticosteroids. (etykieta leku Fluocynonid, Ostrzeżenia i środki ostrożności)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
In this situation, the patient requires immediate reevaluation with reassessment of the treatment regimen, giving special consideration to the possible need for replacing the current strength of Fluticasone Propionate/Salmeterol MDPI with a higher strength, adding additional inhaled corticosteroid, or initiating systemic corticosteroids. (etykieta leku Flutykazon + salmeterol, Ostrzeżenia i środki ostrożności)
Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Estrogens, including oral contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids thereby increasing their effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Use of more than one corticosteroid-containing product at the same time may increase the total systemic exposure to topical corticosteroids. (etykieta leku Halobetazol, Ostrzeżenia i środki ostrożności)
Caution is advised when haloperidol decanoate is used in combination with drugs known to cause electrolyte imbalance (e.g., diuretics or corticosteroids) because hypokalemia, hypomagnesemia, and hypocalcemia are risk factors for QT prolongation. (etykieta leku Haloperydol, Interakcje z innymi lekami)
Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Long-term treatment with steroids may be necessary (see PRECAUTIONS, Laboratory Tests ). (etykieta leku Hydralazyna, Ostrzeżenia)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Hydrokodon, Ostrzeżenia i środki ostrożności)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Hydrokodon + chlorfenamina, Ostrzeżenia i środki ostrożności)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Hydrokodon + homatropina, Ostrzeżenia i środki ostrożności)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Hydrokodon + paracetamol, Ostrzeżenia)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Hydromorfon, Ostrzeżenia i środki ostrożności)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
- IwermektynaUmiarkowana
Oral hydration, recumbency, intravenous normal saline, and/or parenteral corticosteroids have been used to treat postural hypotension. (etykieta leku Iwermektyna, Ostrzeżenia)
Antitubercular drugs: Serum concentrations of isoniazid may be decreased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Prevention or Management Consider a possible decrease in cladribine efficacy if potent BCRP (e.g., corticosteroids) or P-gp (e.g., rifampicin, St. (etykieta leku Kladrybina, Interakcje z innymi lekami)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Kodeina, Ostrzeżenia i środki ostrożności)
Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (etykieta leku Kokaina, Interakcje z innymi lekami)
Cholestyramine: Cholestyramine may increase the clearance of corticosteroids. (etykieta leku Prednizolon, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
…osteonecrosis of the jaw include invasive dental procedures (e.g., tooth extraction, dental implants, boney surgery), diagnosis of cancer, concomitant therapies (e.g., chemotherapy, corticosteroids, angiogenesis inhibitors), poor oral hygiene, and co-morbid disorders (e.g., periodontal and/or other pre-existing dental disease, anemia, coagulopathy, infection, ill-fitting… (etykieta leku Kwas alendronowy, Ostrzeżenia i środki ostrożności)
…osteonecrosis of the jaw include invasive dental procedures (e.g., tooth extraction, dental implants, boney surgery), diagnosis of cancer, concomitant therapies (e.g., chemotherapy, corticosteroids, angiogenesis inhibitors), poor oral hygiene, and co-morbid disorders (e.g., periodontal and/or other pre-existing dental disease, anemia, coagulopathy, infection, ill-fitting… (etykieta leku Kwas ibandronowy, Ostrzeżenia i środki ostrożności)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Many of these patients were also receiving chemotherapy and corticosteroids, which may be risk factors for ONJ. (etykieta leku Kwas pamidronowy, Ostrzeżenia i środki ostrożności)
…the jaw include invasive dental procedures (for example, tooth extraction, dental implants, boney surgery), diagnosis of cancer, concomitant therapies (for example, chemotherapy, corticosteroids, angiogenesis inhibitors), poor oral hygiene, and co-morbid disorders (for example, periodontal and/or other pre-existing dental disease, anemia, coagulopathy, infection,… (etykieta leku Kwas ryzedronowy, Ostrzeżenia i środki ostrożności)
Oral Contraceptive Steroids Administration of a single-dose of ethinyloestradiol (50 mcg)/levonorgestrel (250 mcg) to 6 women on valproate (200 mg BID) therapy for 2 months did not reveal any pharmacokinetic interaction. (etykieta leku Kwas walproinowy, Interakcje z innymi lekami)
A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (etykieta leku Kwas zoledronowy, Ostrzeżenia i środki ostrożności)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
The risk of developing fluoroquinolone-associated tendinitis and tendon rupture is increased in patients usually over 60 years of age, in those taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. (etykieta leku Lewofloksacyna, Ostrzeżenia i środki ostrożności)
Estrogens, including oral contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids thereby increasing their effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Estrogens, including oral contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids thereby increasing their effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Leworfanol, Ostrzeżenia)
If the patient needs more doses of XOPENEX HFA than usual, this may be a marker of destabilization of asthma and requires reevaluation of the patient and treatment regimen, giving special consideration to the possible need for anti-inflammatory treatment, e.g., corticosteroids. (etykieta leku Lewosalbutamol, Ostrzeżenia i środki ostrożności)
Changes in thyroid status of the patient may necessitate adjustment in dosage. (etykieta leku Prednizolon, Ostrzeżenia i środki ostrożności)
Changes in thyroid status of the patient may necessitate adjustment in dosage. (etykieta leku Prednizolon, Ostrzeżenia i środki ostrożności)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Changes in thyroid status of the patient may necessitate adjustment in dosage. (etykieta leku Prednizolon, Ostrzeżenia i środki ostrożności)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Even in those instances where swelling of only the tongue is involved, without respiratory distress, patients may require prolonged observation since treatment with antihistamines and corticosteroids may not be sufficient. (etykieta leku Lizynopryl + hydrochlorotiazyd, Ostrzeżenia)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
- MargetuximabUmiarkowana
In patients who experience mild or moderate IRRs, consider premedications, including antihistamines, corticosteroids, and antipyretics. (etykieta leku Margetuximab, Ostrzeżenia i środki ostrożności)
Estrogens, including oral contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids thereby increasing their effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Estrogens, including oral contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids thereby increasing their effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
- MepolizumabUmiarkowana
Decrease corticosteroids gradually, if appropriate. (etykieta leku Mepolizumab, Ostrzeżenia i środki ostrożności)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Metadon, Ostrzeżenia i środki ostrożności)
Drug Interactions Methazolamide should be used with caution in patients on steroid therapy because of the potential for developing hypokalemia. (etykieta leku Metazolamid, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etykieta leku Metolazon, Interakcje z innymi lekami)
NSAIDs, Aspirin, and Steroids: May elevate and prolong serum methotrexate levels and increase gastrointestinal toxicity. (etykieta leku Metotreksat, Interakcje z innymi lekami)
If not, corticosteroids may be given and other causes of anemia should be considered. (etykieta leku Metyldopa, Ostrzeżenia)
Testosterone has been subject to abuse, typically at doses higher than recommended for the approved indication and in combination with other anabolic androgenic steroids. (etykieta leku Metylotestosteron, Ostrzeżenia)
- MetyraponUmiarkowana
This can be corrected by giving appropriate doses of corticosteroids. (etykieta leku Metyrapon, Ostrzeżenia i środki ostrożności)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
The risk of developing fluoroquinolone-associated tendinitis and tendon rupture is increased in patients over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. (etykieta leku Moksyfloksacyna, Ostrzeżenia i środki ostrożności)
Lung function (FEV 1 or PEF), beta-agonist use, and asthma symptoms should be carefully monitored during withdrawal of oral or other systemic corticosteroids. (etykieta leku Mometazon, Ostrzeżenia i środki ostrożności)
Inhaled corticosteroid may be reduced gradually. (etykieta leku Montelukast, Ostrzeżenia i środki ostrożności)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Morfina, Ostrzeżenia i środki ostrożności)
Effect of Micafungin in Sodium Chloride Injection on Other Drugs CYP3A4 Substrates There was no effect of single or multiple doses of micafungin for injection on cyclosporine, tacrolimus, prednisolone, voriconazole and fluconazole pharmacokinetics. (etykieta leku Mykafungina, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Nalbufina, Ostrzeżenia)
…hypoglycemia concomitant administration of medications that may lower the seizure threshold, including other bupropion products, antipsychotics, tricyclic antidepressants, theophylline, systemic steroids Recommendations for Reducing the Risk of Seizure: Clinical experience with bupropion suggests that the risk of seizure may be minimized by adhering to the recommended… (etykieta leku Naltrekson + bupropion, Ostrzeżenia i środki ostrożności)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
In Studies MS1 and MS2, an increase in infections was seen in patients concurrently receiving short courses of corticosteroids. (etykieta leku Natalizumab, Ostrzeżenia i środki ostrożności)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
- NintedanibUmiarkowana
Use OFEV with caution when treating patients with recent abdominal surgery, previous history of diverticular disease or receiving concomitant corticosteroids or NSAIDs. (etykieta leku Nintedanib, Ostrzeżenia i środki ostrożności)
Estrogens, including oral contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids thereby increasing their effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Estrogens, including oral contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids thereby increasing their effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Estrogens, including oral contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids thereby increasing their effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Estrogens, including oral contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids thereby increasing their effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Estrogens, including oral contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids thereby increasing their effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
The risk of developing fluoroquinolone-associated tendinitis and tendon rupture is increased in patients over 60 years of age, in those taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. (etykieta leku Ofloksacyna, Ostrzeżenia)
In multiple sclerosis (MS) clinical trials, all adult and pediatric patients who were treated with OCREVUS received premedication with methylprednisolone (or an equivalent steroid), and may have also received an antihistamine (all pediatric patients) and/or an analgesic/antipyretic to reduce the risk of infusion reactions prior to each infusion. (etykieta leku Okrelizumab, Ostrzeżenia i środki ostrożności)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Oksykodon, Ostrzeżenia i środki ostrożności)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Oksykodon + paracetamol, Ostrzeżenia i środki ostrożności)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Oksymorfon, Ostrzeżenia i środki ostrożności)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Olicerydyna, Ostrzeżenia i środki ostrożności)
- OmalizumabUmiarkowana
Corticosteroid Reduction: Do not abruptly discontinue corticosteroids upon initiation of OMLYCLO therapy. (etykieta leku Omalizumab, Ostrzeżenia i środki ostrożności)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Paracetamol + kodeina, Ostrzeżenia)
- PasyreotydUmiarkowana
If adrenal insufficiency is suspected, it should be confirmed and treated per standard of care with exogenous glucocorticoids at replacement doses . (etykieta leku Pasyreotyd, Ostrzeżenia i środki ostrożności)
- PenicylaminaUmiarkowana
Treatment has consisted of high doses of corticosteroids alone or, in some cases, concomitantly with an immunosuppressant. (etykieta leku Penicylamina, Ostrzeżenia)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Pentazocyna + nalokson, Ostrzeżenia)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Petydyna, Ostrzeżenia i środki ostrożności)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Pokrzyk wilcza jagoda (belladonna) + opium, Ostrzeżenia i środki ostrożności)
Prior and Concomitant Treatment with Anti-neoplastic, Immune-Modulating, or Immunosuppressive Therapies Anti-neoplastic, immune-modulating, or immunosuppressive therapies (including corticosteroids) should be coadministered with caution because of the risk of additive immune system effects [see Drug Interactions (7.1) ] . (etykieta leku Ponesimod, Ostrzeżenia i środki ostrożności)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Published animal studies show prednisolone to be teratogenic in rats, rabbits, hamsters, and mice with increased incidence of cleft palate in offspring. (etykieta leku Prednizon, Ostrzeżenia i środki ostrożności)
Estrogens, including oral contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids thereby increasing their effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Prometazyna + kodeina, Ostrzeżenia i środki ostrożności)
The following appear to be major risk factors for the development of these events: decreased oxygen delivery to tissues; serious neurological injury and/or sepsis; high dosages of one or more of the following pharmacological agents: vasoconstrictors, steroids, inotropes and/or prolonged, high-dose infusions of propofol (> 5 mg/kg/hour for > 48 hours). (etykieta leku Propofol, Ostrzeżenia i środki ostrożności)
Changes in thyroid status of the patient may necessitate adjustment in dosage. (etykieta leku Prednizolon, Ostrzeżenia i środki ostrożności)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Therefore, for patients receiving both neuromuscular blocking agents (including Rocuronium Bromide Injection) and corticosteroids, the period of use of the neuromuscular blocking agent should be limited as much as possible and only used in the setting where in the opinion of the prescribing physician, the specific advantages of the drug outweigh the risk. (etykieta leku Rokuronium, Ostrzeżenia i środki ostrożności)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
If the patient needs more doses of Albuterol Sulfate HFA than usual, this may be a marker of destabilization of asthma and requires reevaluation of the patient and treatment regimen, giving special consideration to the possible need for anti-inflammatory treatment, e.g., corticosteroids. (etykieta leku Salbutamol, Ostrzeżenia i środki ostrożności)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
The neuromuscular blocking effect of succinylcholine may be enhanced by drugs that reduce plasma cholinesterase activity (e.g., chronically administered oral contraceptives, glucocorticoids, or certain monoamine oxidase inhibitors) or by drugs that irreversibly inhibit plasma cholinesterase [see Warnings and Precautions (5.9) ]. (etykieta leku Suksametonium, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Tapentadol, Ostrzeżenia i środki ostrożności)
- TemozolomidUmiarkowana
Pneumocystis Pneumonia (PCP) : Closely monitor all patients, particularly those receiving steroids, for the development of lymphopenia and PCP. (etykieta leku Temozolomid, Ostrzeżenia i środki ostrożności)
- TemsyrolimusUmiarkowana
If ILD is suspected, discontinue TORISEL, and consider use of corticosteroids and/or antibiotics. (etykieta leku Temsyrolimus, Ostrzeżenia i środki ostrożności)
Dosage Increases: Increases in the dose of theophylline should not be made in response to an acute exacerbation of symptoms of chronic lung disease since theophylline provides little added benefit to inhaled beta2 -selective agonists and systemically administered corticosteroids in this circumstance and increases the risk of adverse effects. (etykieta leku Teofilina, Ostrzeżenia)
If the patient needs more doses of terbutaline sulfate tablets than usual, this may be a marker of destabilization of asthma and requires reevaluation of the patient and the treatment regimen, giving special consideration to the possible need for anti-inflammatory treatment, e.g., corticosteroids. (etykieta leku Terbutalina, Ostrzeżenia)
Changes in thyroid status of the patient may necessitate adjustment in dosage. (etykieta leku Prednizolon, Ostrzeżenia i środki ostrożności)
- TesamorelinaUmiarkowana
Glucocorticoids : Patients receiving glucocorticoid replacement for previously diagnosed hypoadrenalism may require an increase in maintenance or stress doses following initiation of EGRIFTA SV. (etykieta leku Tesamorelina, Interakcje z innymi lekami)
Abuse of Testosterone and Monitoring of Serum Testosterone : If testosterone use at doses higher than recommended for the approved indication and in combination with other anabolic androgenic steroids is suspected, check serum testosterone concentration ( 5.5 ). (etykieta leku Testosteron, Ostrzeżenia i środki ostrożności)
Changes in thyroid status of the patient may necessitate adjustment in dosage. (etykieta leku Prednizolon, Ostrzeżenia i środki ostrożności)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Concomitant Respiratory Medications SPIRIVA RESPIMAT has been used concomitantly with short-acting and long-acting sympathomimetic (beta-agonists) bronchodilators, methylxanthines, oral and inhaled steroids, antihistamines, mucolytics, leukotriene modifiers, cromones, and anti-IgE treatment without increases in adverse reactions. (etykieta leku Tiotropium, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inducers (e.g. barbiturates, phenytoin, carbamazepine, and rifampin): Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Orapred be increased. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Corticosteroids and ACTH: Increased risk of hypokalemia. (etykieta leku Torasemid, Interakcje z innymi lekami)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Tramadol, Ostrzeżenia i środki ostrożności)
If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Tramadol + paracetamol, Ostrzeżenia i środki ostrożności)
- TrastuzumabUmiarkowana
Interrupt TRAZIMERA infusion in all patients experiencing dyspnea, clinically significant hypotension, and intervention of medical therapy administered (which may include epinephrine, corticosteroids, diphenhydramine, bronchodilators, and oxygen). (etykieta leku Trastuzumab, Ostrzeżenia i środki ostrożności)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (etykieta leku Triamteren + hydrochlorotiazyd, Interakcje z innymi lekami)
Antidiabetic Agents: Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
CYP 3A4 inhibitors (e.g., ketoconazole, macrolide antibiotics): Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Prednizolon, Interakcje z innymi lekami)
- ZenocutuzumabUmiarkowana
Prior to the first BIZENGRI infusion, premedicate with a corticosteroid, an H1 antihistamine and acetaminophen to reduce the risk of IRRs [see Dosage and Administration (2.4) ]. (etykieta leku Zenocutuzumab, Ostrzeżenia i środki ostrożności)
Wzmianki o niewielkim znaczeniu (82)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
- AlteplazaNiewielka
If signs of hypersensitivity occur, e.g. anaphylactoid reaction or angioedema develops, discontinue the Activase infusion and promptly institute appropriate therapy (e.g., antihistamines, intravenous corticosteroids, epinephrine). (etykieta leku Alteplaza, Ostrzeżenia i środki ostrożności)
Drug/Laboratory Test Interactions Amphetamines can cause a significant elevation in plasma corticosteroid levels. (etykieta leku Amfetamina, Interakcje z innymi lekami)
Interference with Laboratory Tests Amphetamines can cause a significant elevation in plasma corticosteroid levels. (etykieta leku Amfetamina + deksamfetamina, Interakcje z innymi lekami)
Most patients with hypersensitivity pneumonitis discontinued treatment with ARIKAYCE and received treatment with corticosteroids [see Adverse Reactions (6.1) ] . (etykieta leku Amikacyna, Ostrzeżenia i środki ostrożności)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
OXYGEN, INTRAVENOUS STEROIDS, AND AIRWAY MANAGEMENT, INCLUDING INTUBATION, SHOULD ALSO BE ADMINISTERED AS INDICATED. (etykieta leku Ampicylina, Ostrzeżenia)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Oxygen, intravenous steroids, and airway management, including intubation, should also be administered as indicated. (etykieta leku Benzylopenicylina, Ostrzeżenia)
- BewacyzumabNiewielka
Discontinue in patients who develop a severe infusion-related reaction and administer appropriate medical therapy (e.g., epinephrine, corticosteroids, intravenous antihistamines, bronchodilators and/or oxygen). (etykieta leku Bewacyzumab, Ostrzeżenia i środki ostrożności)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
- BusulfanNiewielka
The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (etykieta leku Busulfan, Ostrzeżenia)
SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (etykieta leku Cefadroksyl, Ostrzeżenia i środki ostrożności)
SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (etykieta leku Cefaklor, Ostrzeżenia)
SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (etykieta leku Cefdynir, Ostrzeżenia)
SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (etykieta leku Cefotetan, Ostrzeżenia)
SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (etykieta leku Cefprozyl, Ostrzeżenia)
SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, IV FLUIDS, IV ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (etykieta leku Ceftazydym, Ostrzeżenia)
Serious acute hypersensitivity reactions may require treatment with epinephrine and other emergency measures including oxygen, corticosteroids, intravenous fluids, intravenous antihistamines, pressor amines, and airway management, as clinically indicated. (etykieta leku Ceftriakson, Ostrzeżenia i środki ostrożności)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Drug/Laboratory Interactions Quinine may produce an elevated value for urinary 17-ketogenic steroids when the Zimmerman method is used. (etykieta leku Chinina, Interakcje z innymi lekami)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
- DazatynibNiewielka
Fluid retention events were typically managed by supportive care measures that may include diuretics or short courses of steroids. (etykieta leku Dazatynib, Ostrzeżenia i środki ostrożności)
Drug/Laboratory Test Interactions Amphetamines can cause a significant elevation in plasma corticosteroid levels. (etykieta leku Deksamfetamina, Interakcje z innymi lekami)
Anticholinesterase agents: Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (etykieta leku Prednizolon, Interakcje z innymi lekami)
These would include diuretics, laxatives and supraphysiological use of steroid hormones with mineralocorticoid potential. (etykieta leku Droperydol, Interakcje z innymi lekami)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
OXYGEN, INTRAVENOUS STEROIDS, AND AIRWAY MANAGEMENT, INCLUDING INTUBATION, SHOULD ALSO BE ADMINISTERED AS INDICATED. (etykieta leku Fenoksymetylopenicylina, Ostrzeżenia)
Anticholinesterase agents: Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Steroids may or may not be effective in controlling these hemolytic episodes. (etykieta leku Fludarabina, Ostrzeżenia i środki ostrożności)
Since mineralocorticoid secretion may be impaired, salt and/or a mineralocorticoid should be administered concurrently. (etykieta leku Prednizolon, Ostrzeżenia i środki ostrożności)
Most patients improved promptly with discontinuation of fluoxetine and/or adjunctive treatment with antihistamines or steroids, and all patients experiencing these reactions were reported to recover completely. (etykieta leku Fluoksetyna, Ostrzeżenia i środki ostrożności)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Anticholinesterase agents: Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (etykieta leku Prednizolon, Interakcje z innymi lekami)
- GlukagonNiewielka
In the reported cases NME resolved with discontinuation of the glucagon, and treatment with corticosteroids was not effective. (etykieta leku Glukagon, Ostrzeżenia i środki ostrożności)
TREMFYA was subsequently discontinued, and the liver test abnormalities resolved following administration of corticosteroids [see Adverse Reactions (6.1) ] . (etykieta leku Guselkumab, Ostrzeżenia i środki ostrożności)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Amphotericin B: There have been cases reported in which concomitant use of Amphotericin B and hydrocortisone was followed by cardiac enlargement and congestive heart failure (see also Potassium depleting agents). (etykieta leku Prednizolon, Interakcje z innymi lekami)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
ATROVENT HFA has been used concomitantly with other drugs, including sympathomimetic bronchodilators, methylxanthines, oral and inhaled steroids commonly used in the treatment of COPD. (etykieta leku Ipratropium, Interakcje z innymi lekami)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Corticosteroids A relationship of functional antagonism exists between vitamin D analogues, which promote calcium absorption, and corticosteroids, which inhibit calcium absorption. (etykieta leku Kalcytriol, Interakcje z innymi lekami)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Some subjects in the EPIDIOLEX clinical trials had pruritus, erythema, and angioedema requiring treatment, including corticosteroids and antihistamines. (etykieta leku Kannabidiol (na receptę), Ostrzeżenia i środki ostrożności)
The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (etykieta leku Klofarabina, Ostrzeżenia i środki ostrożności)
Elevated urinary steroid levels, varying degrees of electrolyte imbalance, hypovolemia, hemoconcentration, and hypoproteinemia may occur. (etykieta leku Klomifen, Ostrzeżenia)
- KortykotropinaNiewielka
The recovery of the adrenal gland may take from days to months so patients should be protected from the stress (e.g., trauma or surgery) by the use of corticosteroids during the period of stress. (etykieta leku Kortykotropina, Ostrzeżenia i środki ostrożności)
Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (etykieta leku Kwas bempedoinowy, Ostrzeżenia i środki ostrożności)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
- LenalidomidNiewielka
Patients with Grade 1 and 2 TFR may also be treated with corticosteroids, non-steroidal anti-inflammatory drugs (NSAIDs) and/or narcotic analgesics for management of TFR symptoms. (etykieta leku Lenalidomid, Ostrzeżenia i środki ostrożności)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
- MelfalanNiewielka
The infusion should be terminated immediately, followed by the administration of volume expanders, pressor agents, corticosteroids, or antihistamines at the discretion of the physician. (etykieta leku Melfalan, Ostrzeżenia)
Anticholinesterase agents: Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Drug/Laboratory Test Interactions Amphetamines can cause a significant elevation in plasma corticosteroid levels. (etykieta leku Metamfetamina, Interakcje z innymi lekami)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Midodrine hydrochloride has been used in patients concomitantly treated with salt-retaining steroid therapy (i.e., fludrocortisone acetate), with or without salt supplementation. (etykieta leku Midodryna, Interakcje z innymi lekami)
- MitoksantronNiewielka
Following concurrent administration of mitoxantrone injection with corticosteroids, no evidence of drug interactions has been observed. (etykieta leku Mitoksantron, Interakcje z innymi lekami)
Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (etykieta leku Naltrekson, Ostrzeżenia i środki ostrożności)
Anticholinesterase agents: Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (etykieta leku Prednizolon, Interakcje z innymi lekami)
If an allergic reaction occurs, the drug should be discontinued and the patient should receive supportive treatment, e.g. , artificial maintenance of ventilation, pressor amines, antihistamines, and corticosteroids. (etykieta leku Oksacylina, Ostrzeżenia)
Most patients improved promptly with discontinuation of fluoxetine and/or adjunctive treatment with antihistamines or steroids, and all patients experiencing these reactions were reported to recover completely. (etykieta leku Olanzapina + fluoksetyna, Ostrzeżenia i środki ostrożności)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Anticholinesterase agents: Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Other Concomitant Medications EVISTA can be concomitantly administered with ampicillin, amoxicillin, antacids, corticosteroids, and digoxin [see Clinical Pharmacology ( 12.3 )] . (etykieta leku Raloksyfen, Interakcje z innymi lekami)
Institute medical management (e.g., glucocorticoids, epinephrine, bronchodilators, or oxygen) for infusion-related reactions as needed. (etykieta leku Rytuksymab, Ostrzeżenia i środki ostrożności)
Anticholinesterase agents: Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
- TenekteplazaNiewielka
If symptoms of hypersensitivity occur, initiate appropriate therapy (e.g., antihistamines, corticosteroids, epinephrine). (etykieta leku Tenekteplaza, Ostrzeżenia i środki ostrożności)
In clinical studies, patients receiving TOBI Podhaler continued to take dornase alfa, bronchodilators, inhaled corticosteroids, and macrolides. (etykieta leku Tobramycyna, Interakcje z innymi lekami)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Patients improved with discontinuation of therapy and in certain cases administration of corticosteroids. (etykieta leku Ustekinumab, Ostrzeżenia i środki ostrożności)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)
Kortykosteroidy, takie jak prednizon, zmniejszają wchłanianie wapnia i zaburzają metabolizm witaminy D, przyczyniając się do utraty masy kostnej. (NIH Office of Dietary Supplements, Vitamin D)
Most patients improved promptly with adjunctive treatment with antihistamines or steroids and/or upon discontinuation of ziprasidone, and all patients experiencing these reactions were reported to recover completely. (etykieta leku Zyprazydon, Ostrzeżenia i środki ostrożności)
Nie zgłoszono istotnej interakcji (1)
…vaccine ketoconazole lomefloxacin mebendazole medroxyprogesterone methylprednisolone metronidazole metoprolol nadolol nifedipine nizatidine norfloxacin ofloxacin omeprazole prednisone, prednisolone ranitidine rifabutin roxithromycin sorbitol (purgative doses do not inhibit theophylline absorption) sucralfate terbutaline, systemic terfenadine tetracycline tocainide… (etykieta leku Aminofilina, Interakcje z innymi lekami)
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