Triamteren: interakcje

Dyrenium should not be given to patients receiving other potassium-sparing agents, such as spironolactone, amiloride hydrochloride, or other formulations containing triamterene. (etykieta leku Triamteren, Przeciwwskazania)

WARNING Bumetanide is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. (etykieta leku Bumetanid, Ostrzeżenie w ramce)

…sometimes associated with oliguria and/or progressive azotemia, and rarely with acute renal failure and/or death, include patients with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis, or severe volume and/or salt depletion of any etiology. (etykieta leku Chinapryl, Ostrzeżenia)

…sometimes associated with oliguria and/or progressive azotemia, and rarely acute renal failure and/or death, include patients with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis or severe volume and/or salt depletion of any etiology. (etykieta leku Chinapryl + hydrochlorotiazyd, Ostrzeżenia)

Potassium chloride is contraindicated in patients on triamterene and amiloride. (etykieta leku Chlorek potasu, Przeciwwskazania)

Because the use of diuretics can accentuate the diminished intravascular volume, avoid diuretics except in the late phase of resolution. (etykieta leku Choriogonadotropina alfa, Ostrzeżenia)

Potassium-Sparing Diuretics Cyclosporine should not be used with potassium-sparing diuretics because hyperkalemia can occur. (etykieta leku Cyklosporyna, Interakcje z innymi lekami)

Such conditions include: chronic renal failure, uncontrolled diabetes mellitus, acute dehydration, strenuous physical exercise in unconditioned individuals, adrenal insufficiency, extensive tissue breakdown or the administration of a potassium-sparing agent (such as triamterene, spironolactone or amiloride). (etykieta leku Cytrynian potasu, Przeciwwskazania)

The concomitant use of hydrochlorothiazide (alone or in combinations such as with triamterene) with dofetilide is contraindicated (see PRECAUTIONS, Drug-Drug Interactions ) because this has been shown to significantly increase dofetilide plasma concentrations and QT interval prolongation. (etykieta leku Dofetylid, Przeciwwskazania)

Droperidol should be administered with extreme caution to patients who may be at risk for development of prolonged QT syndrome (e.g., congestive heart failure, bradycardia, use of a diuretic, cardiac hypertrophy, hypokalemia, hypomagnesemia, or administration of other drugs known to increase the QT interval). (etykieta leku Droperydol, Ostrzeżenie w ramce)

Avoid potassium sparing agents in patients with heart failure ( 7.3 ). (etykieta leku Enalapryl, Interakcje z innymi lekami)

…sometimes associated with oliguria and/or progressive azotemia, and rarely with acute renal failure and/or death, include those with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis, or severe volume and/or salt depletion of any etiology. (etykieta leku Enalaprylat, Ostrzeżenia)

Dyrenium should not be given to patients receiving other potassium-sparing agents, such as spironolactone, amiloride hydrochloride, or other formulations containing triamterene. (etykieta leku Triamteren, Przeciwwskazania)

…of active abnormal bleeding within the previous 30 days Severe hypertension (systolic blood pressure >200 mm Hg or diastolic blood pressure >110 mm Hg) not adequately controlled on antihypertensive therapy Major surgery within the preceding 6 weeks History of stroke within 30 days or any history of hemorrhagic stroke Current or planned administration of another… (etykieta leku Eptyfibatyd, Przeciwwskazania)

Because the use of diuretics can accentuate the diminished intravascular volume, diuretics should be avoided except in the late phase of resolution as described below. (etykieta leku Folitropina, Ostrzeżenia i środki ostrożności)

The concurrent use of gentamicin with potent diuretics, such as ethacrynic acid or furosemide, should be avoided, since certain diuretics by themselves may cause ototoxicity. (etykieta leku Gentamycyna, Ostrzeżenie w ramce)

• GI Toxicity with Solid Oral Dosage Forms of Potassium Chloride : Concomitant use is not recommended. (etykieta leku Glikopironium, Interakcje z innymi lekami)

Indomethacin and triamterene should not be administered together. (etykieta leku Indometacyna, Ostrzeżenia i środki ostrożności)

Avoid diuretics or laxatives in patients with diarrhea. (etykieta leku Irynotekan, Ostrzeżenia i środki ostrożności)

Diuretics Eplerenone Contraindicated during and 2 weeks after TOLSURA treatment. (etykieta leku Itrakonazol, Interakcje z innymi lekami)

Use CLOZARIL cautiously in patients with cardiovascular or cerebrovascular disease or conditions predisposing to hypotension (e.g., dehydration, use of antihypertensive medications) [see Dosage and Administration ( 2.2 , 2.6 ), Warnings and Precautions ( 5.2 )]. (etykieta leku Klozapina, Ostrzeżenie w ramce)

CONTRAINDICATIONS All diuretics, including ethacrynic acid, are contraindicated in anuria. (etykieta leku Kwas etakrynowy, Przeciwwskazania)

Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etykieta leku Metolazon, Ostrzeżenia)

Minoxidil should be reserved for hypertensive patients who do not respond adequately to maximum therapeutic doses of a diuretic and two other antihypertensive agents. (etykieta leku Minoksydyl, Ostrzeżenie w ramce)

The concurrent use of neomycin with potent diuretics such as ethacrynic acid or furosemide should be avoided, since certain diuretics by themselves may cause ototoxicity. (etykieta leku Neomycyna, Ostrzeżenie w ramce)

Patients should not be placed on dietary potassium supplements, potassium salts or potassium-containing salt substitutes in conjunction with Dyrenium. (etykieta leku Triamteren, Przeciwwskazania)

Two deaths have been reported in patients receiving concomitant spironolactone and Dyrenium or Dyazide ® . (etykieta leku Triamteren, Przeciwwskazania)

Two deaths have been reported in patients receiving concomitant spironolactone and Dyrenium or Dyazide ® . (etykieta leku Triamteren, Przeciwwskazania)

…coadministration of an alpha-blocker and CIALIS for the treatment of BPH has not been adequately studied, and due to the potential vasodilatory effects of combined use resulting in blood pressure lowering, the combination of CIALIS and alpha-blockers is not recommended for the treatment of BPH. [see Dosage and Administration ( 2.7 ), Drug Interactions ( 7.1 ),… (etykieta leku Tadalafil, Ostrzeżenia i środki ostrożności)

Dyrenium should not be given to patients receiving other potassium-sparing agents, such as spironolactone, amiloride hydrochloride, or other formulations containing triamterene. (etykieta leku Triamteren, Przeciwwskazania)

The risk of torsade de pointes is related to the extent of QTc prolongation, concomitant administration of QTc prolonging drugs, a history of torsade de pointes, pre-existing QTc interval prolongation, congestive heart failure, administration of potassium-wasting diuretics, or other conditions that result in hypokalemia or hypomagnesemia. (etykieta leku Trójtlenek arsenu, Ostrzeżenia i środki ostrożności)

Sodium bicarbonate injection is contraindicated in patients who are losing chloride by vomiting or from continuous gastrointestinal suction and in patients receiving diuretics known to produce a hypochloremic alkalosis. (etykieta leku Wodorowęglan sodu, Przeciwwskazania)

Although β-blockers should be avoided in overt cardiac failure, acebutolol can be used with caution in patients with a history of heart failure who are controlled with digitalis and/or diuretics. (etykieta leku Acebutolol, Ostrzeżenia)

The effects of the following drugs may be potentiated when given together with triamterene: antihypertensive medication, other diuretics, preanesthetic and anesthetic agents, skeletal muscle relaxants (non-depolarizing). (etykieta leku Triamteren, Interakcje z innymi lekami)

…Precautions (5.6) and Adverse Reactions (6) ]. β-blockers, such as propranolol Cyclopropane or halogenated hydrocarbon anesthetics, such as halothane Antihistamines Thyroid hormones Diuretics Cardiac glycosides, such as digitalis glycosides Quinidine Drugs potentiating hypokalemic effects of epinephrine • Potassium depleting diuretics • Corticosteroids • Theophylline… (etykieta leku Adrenalina, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Postural hypotension/syncope: Care should be taken in patients with symptomatic hypotension or who have had a hypotensive response to other medications or are concomitantly treated with antihypertensive medication or nitrates ( 5.1 ) (etykieta leku Alfuzosyna, Ostrzeżenia i środki ostrożności)

Risk factors for the development of hyperkalemia include renal insufficiency, diabetes, combination use with ARBs or ACEIs [see Contraindications ( 4 ), Warnings and Precautions ( 5.2 ), and Clinical Studies ( 14.3 )] , NSAIDs, or potassium supplements or potassium sparing diuretics. (etykieta leku Aliskiren, Ostrzeżenia i środki ostrożności)

Hypersensitivity reactions to allopurinol tablets may be increased in patients with decreased kidney function receiving thiazide diuretics and allopurinol tablets concurrently. (etykieta leku Allopurynol, Ostrzeżenia i środki ostrożności)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

The pressor effects of diethylpropion and those of other drugs may be additive when the drugs are used concomitantly; conversely, diethylpropion may interfere with antihypertensive drugs (i.e., guanethidine, a-methyldopa). (etykieta leku Amfepramon (dietylopropion), Interakcje z innymi lekami)

Ethacrynic Acid, Furosemide, Urea, or Mannitol Some diuretics can enhance aminoglycoside toxicity by altering aminoglycoside concentrations in serum and tissue. (etykieta leku Amikacyna, Interakcje z innymi lekami)

Give special attention to electrolyte and acid-base balance in patients experiencing severe or prolonged diarrhea or in patients receiving concomitant diuretics and laxatives. (etykieta leku Amiodaron, Ostrzeżenia i środki ostrożności)

Potassium-sparing agents should be used with caution in conjunction with angiotensin-converting enzyme (ACE) inhibitors due to an increased risk of hyperkalemia. (etykieta leku Triamteren, Interakcje z innymi lekami)

In patients with an activated renin-angiotensin system, such as volume and/or salt-depleted patients (e.g., those being treated with high doses of diuretics) symptomatic hypotension may be anticipated after initiation of treatment with olmesartan medoxomil . (etykieta leku Amlodypina + olmesartan, Ostrzeżenia i środki ostrożności)

In patients with an activated renin-angiotensin system, such as volume- and/or salt-depleted patients receiving high doses of diuretics, symptomatic hypotension may occur in patients receiving angiotensin receptor blockers. (etykieta leku Amlodypina + walsartan, Ostrzeżenia i środki ostrożności)

…from blood bank (may contain up to 30 mEq of potassium per liter of plasma or up to 65 mEq per liter of whole blood when stored for more than 10 days); low-salt milk (may contain up to 60 mEq of potassium per liter); potassium-containing medications (such as parenteral penicillin G potassium); salt substitutes (most contain substantial amounts of potassium). (etykieta leku Triamteren, Interakcje z innymi lekami)

…from blood bank (may contain up to 30 mEq of potassium per liter of plasma or up to 65 mEq per liter of whole blood when stored for more than 10 days); low-salt milk (may contain up to 60 mEq of potassium per liter); potassium-containing medications (such as parenteral penicillin G potassium); salt substitutes (most contain substantial amounts of potassium). (etykieta leku Triamteren, Interakcje z innymi lekami)

…from blood bank (may contain up to 30 mEq of potassium per liter of plasma or up to 65 mEq per liter of whole blood when stored for more than 10 days); low-salt milk (may contain up to 60 mEq of potassium per liter); potassium-containing medications (such as parenteral penicillin G potassium); salt substitutes (most contain substantial amounts of potassium). (etykieta leku Triamteren, Interakcje z innymi lekami)

…from blood bank (may contain up to 30 mEq of potassium per liter of plasma or up to 65 mEq per liter of whole blood when stored for more than 10 days); low-salt milk (may contain up to 60 mEq of potassium per liter); potassium-containing medications (such as parenteral penicillin G potassium); salt substitutes (most contain substantial amounts of potassium). (etykieta leku Triamteren, Interakcje z innymi lekami)

Xanthine derivatives, steroids, diuretics, or non-potassium sparing diuretics may potentiate hypokalemia or ECG changes. (etykieta leku Arformoterol, Interakcje z innymi lekami)

There was also a slightly greater proportion of patients on NUVIGIL requiring new or increased use of antihypertensive medications (2.9%) compared to patients on placebo (1.8%). (etykieta leku Armodafinil, Ostrzeżenia i środki ostrożności)

Antihypertensive Drugs Due to its alpha-adrenergic antagonism, aripiprazole has the potential to enhance the effect of certain antihypertensive agents. (etykieta leku Arypiprazol, Interakcje z innymi lekami)

Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (elderly patients, patients with dehydration, hypovolemia, concomitant treatment with antihypertensive medications, patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure, or conduction abnormalities), and patients… (etykieta leku Asenapina, Ostrzeżenia i środki ostrożności)

Because of its relative beta 1 selectivity, however, TENORMIN may be used with caution in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. (etykieta leku Atenolol, Ostrzeżenia)

If the ECG shows no widening of the QRS or arrhythmia in the presence of hyperkalemia, it is usually sufficient to discontinue Dyrenium (triamterene) and any potassium supplementation, and substitute a thiazide alone. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

Antihypertensive Drugs Prevention or Management Increase the frequency of monitoring blood pressure and adjust atomoxetine oral solution dosage as clinically appropriate. (etykieta leku Atomoksetyna, Interakcje z innymi lekami)

• Use of avanafil with alpha-blockers, other antihypertensives, or substantial amounts of alcohol (greater than 3 units) may lead to hypotension ( 2.3 , 5.6 , 5.7 ) (etykieta leku Awanafil, Ostrzeżenia i środki ostrożności)

Hypotension in Volume- or Salt-Depleted Patients In patients with an activated renin-angiotensin system, such as volume- and/or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of treatment with azilsartan medoxomil. (etykieta leku Azylsartan, Ostrzeżenia i środki ostrożności)

The effects of the following drugs may be potentiated when given together with triamterene: antihypertensive medication, other diuretics, preanesthetic and anesthetic agents, skeletal muscle relaxants (non-depolarizing). (etykieta leku Triamteren, Interakcje z innymi lekami)

Potassium-sparing agents should be used with caution in conjunction with angiotensin-converting enzyme (ACE) inhibitors due to an increased risk of hyperkalemia. (etykieta leku Triamteren, Interakcje z innymi lekami)

If the ECG shows no widening of the QRS or arrhythmia in the presence of hyperkalemia, it is usually sufficient to discontinue Dyrenium (triamterene) and any potassium supplementation, and substitute a thiazide alone. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

Amphetamines may decrease the hypotensive effect of antihypertensives. (etykieta leku Benzfetamina, Interakcje z innymi lekami)

…from blood bank (may contain up to 30 mEq of potassium per liter of plasma or up to 65 mEq per liter of whole blood when stored for more than 10 days); low-salt milk (may contain up to 60 mEq of potassium per liter); potassium-containing medications (such as parenteral penicillin G potassium); salt substitutes (most contain substantial amounts of potassium). (etykieta leku Triamteren, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Because of its relative beta 1 -selectivity, however, BISOPROLOL FUMARATE may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (etykieta leku Bisoprolol, Ostrzeżenia)

If the ECG shows no widening of the QRS or arrhythmia in the presence of hyperkalemia, it is usually sufficient to discontinue Dyrenium (triamterene) and any potassium supplementation, and substitute a thiazide alone. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etykieta leku Bortezomib, Ostrzeżenia i środki ostrożności)

Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, concomitant treatment with antihypertensive medication), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (etykieta leku Brekspiprazol, Ostrzeżenia i środki ostrożności)

Central Nervous System (CNS) depressants Antihistamines have additive effects with alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers, antianxiety agents, etc.). Antihypertensive drugs Sympathomimetic may reduce the effects of antihypertensive drugs. (etykieta leku Bromfeniramina + pseudoefedryna + dekstrometorfan, Interakcje z innymi lekami)

Use caution in patients taking antihypertensive medications. (etykieta leku Bromokryptyna, Ostrzeżenia i środki ostrożności)

Antihypertensives/Cardiac Glycosides Because brimonidine tartrate ophthalmic solution 0.1% and 0.15% may reduce blood pressure, caution in using drugs such as antihypertensives and/or cardiac glycosides with brimonidine tartrate ophthalmic solution 0.1% and 0.15% is advised. (etykieta leku Brymonidyna, Interakcje z innymi lekami)

Antihypertensives/Cardiac Glycosides Because brimonidine tartrate/timolol maleate ophthalmic solution may reduce blood pressure, caution in using drugs such as antihypertensives and/or cardiac glycosides with brimonidine tartrate/timolol maleate ophthalmic solution is advised. (etykieta leku Brymonidyna + tymolol, Interakcje z innymi lekami)

Diuretics: Use with caution. (etykieta leku Budezonid + formoterol, Interakcje z innymi lekami)

Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Buprenorfina, Interakcje z innymi lekami)

Examples: Cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Buprenorfina + nalokson, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Butalbital + paracetamol + kofeina + kodeina, Interakcje z innymi lekami)

Diuretics: Nephrotoxicity has been reported with concomitant administration of cephalosporins with potent diuretics such as furosemide. (etykieta leku Cefepim, Interakcje z innymi lekami)

Drug Interactions Nephrotoxicity has been reported following concomitant administration of cephalosporins with aminoglycoside antibacterial drugs or potent diuretics such as furosemide. (etykieta leku Ceftazydym, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Drugs that alkalinize the urine ( carbonic-anhydrase inhibitors, sodium bicarbonate, thiazide diuretics ) reduce renal elimination of quinidine. (etykieta leku Chinidyna, Interakcje z innymi lekami)

Drugs That Increase the Risk of Hypercalcemia Increase frequency of monitoring of calcium concentrations in patients taking concomitant Calcium Chloride Injection and other drugs that increase the risk of hypercalcemia (e.g., calcipotriene, estrogen, lithium, parathyroid hormone, teriparatide, thiazide diuretics, Vitamin A, and Vitamin D). (etykieta leku Chlorek wapnia, Interakcje z innymi lekami)

If the ECG shows no widening of the QRS or arrhythmia in the presence of hyperkalemia, it is usually sufficient to discontinue Dyrenium (triamterene) and any potassium supplementation, and substitute a thiazide alone. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etykieta leku Chlorpromazyna, Środki ostrożności)

If the ECG shows no widening of the QRS or arrhythmia in the presence of hyperkalemia, it is usually sufficient to discontinue Dyrenium (triamterene) and any potassium supplementation, and substitute a thiazide alone. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

The effects of the following drugs may be potentiated when given together with triamterene: antihypertensive medication, other diuretics, preanesthetic and anesthetic agents, skeletal muscle relaxants (non-depolarizing). (etykieta leku Triamteren, Interakcje z innymi lekami)

The effects of the following drugs may be potentiated when given together with triamterene: antihypertensive medication, other diuretics, preanesthetic and anesthetic agents, skeletal muscle relaxants (non-depolarizing). (etykieta leku Triamteren, Interakcje z innymi lekami)

…inhibitors can cause leukopenia. ● Natalizumab ● Paclitaxel: Increased hematotoxicity has been reported when cyclophosphamide was administered after paclitaxel infusion. ● Thiazide diuretics ● Zidovudine Increased cardiotoxicity ● Anthracyclines ● Cytarabine ● Pentostatin ● Radiation therapy of the cardiac region ● Trastuzumab Increased pulmonary toxicity ● Amiodarone… (etykieta leku Cyklofosfamid, Interakcje z innymi lekami)

Increase the dose of diuretics as needed [see Adverse Reactions (6) ] . (etykieta leku Cyklokrzemian sodowo-cyrkonowy, Ostrzeżenia i środki ostrożności)

Elderly patients, patients taking diuretics, and those who are volume depleted may be at greater risk for developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (etykieta leku Cytalopram, Ostrzeżenia i środki ostrożności)

The effects of the following drugs may be potentiated when given together with triamterene: antihypertensive medication, other diuretics, preanesthetic and anesthetic agents, skeletal muscle relaxants (non-depolarizing). (etykieta leku Triamteren, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (etykieta leku Dekslanzoprazol, Ostrzeżenia i środki ostrożności)

• Antihypertensive Drugs: Monitor blood pressure. (etykieta leku Deksmetylofenidat, Interakcje z innymi lekami)

The effects of the following drugs may be potentiated when given together with triamterene: antihypertensive medication, other diuretics, preanesthetic and anesthetic agents, skeletal muscle relaxants (non-depolarizing). (etykieta leku Triamteren, Interakcje z innymi lekami)

…Hyponatremia Concomitant administration of DESMODA with other drugs that may increase the risk of water intoxication with hyponatremia, (e.g., tricyclic antidepressants, selective serotonin re-uptake inhibitors, chlorpromazine, opiate analgesics, thiazide diuretics, NSAIDs, lamotrigine, sulfonylureas, particularly chlorpropamide, oxybutynin and carbamazepine). (etykieta leku Desmopresyna, Interakcje z innymi lekami)

Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk [see Use in Specific Populations (8.5) and Clinical Pharmacology (12.3) ] . (etykieta leku Deswenlafaksyna, Ostrzeżenia i środki ostrożności)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with NORPRAMIN. (etykieta leku Dezypramina, Ostrzeżenia)

The concomitant administration of thiazides or other diuretics may potentiate the hyperglycemic and hyperuricemic effects of PROGLYCEM. (etykieta leku Diazoksyd, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Serum potassium levels should be carefully monitored when digoxin is given to patients at high risk of hypokalemia ( e.g. , those receiving diuretics, corticosteroids, or other drugs that commonly lead to potassium loss; those with gastrointestinal losses through diarrhea, vomiting, or nasogastric suction; or those with potassium-losing endocrinopathies or nephropathies). (etykieta leku Digoksyna, Ostrzeżenia i środki ostrożności)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Drugs that Cause Hypokalemia The risk of hypokalemia is greater with coadministration of KEVEYIS and other drugs that can cause hypokalemia (e.g., loop diuretics, thiazide diuretics, laxatives, antifungals, penicillins, and theophylline) [see Warnings and Precautions (5.3) ] . (etykieta leku Diklofenamid, Interakcje z innymi lekami)

…from blood bank (may contain up to 30 mEq of potassium per liter of plasma or up to 65 mEq per liter of whole blood when stored for more than 10 days); low-salt milk (may contain up to 60 mEq of potassium per liter); potassium-containing medications (such as parenteral penicillin G potassium); salt substitutes (most contain substantial amounts of potassium). (etykieta leku Triamteren, Interakcje z innymi lekami)

Risk may be increased when used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (etykieta leku Dokserkalcyferol, Ostrzeżenia i środki ostrożności)

Medications that may increase serum potassium concentration include ACE inhibitors, angiotensin-II receptor antagonists, potassium-sparing diuretics, potassium supplementation, heparin, aldosterone antagonists, and NSAIDS. (etykieta leku Drospirenon + etynyloestradiol, Ostrzeżenia i środki ostrożności)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

The risk of BP decreases may be greater in patients taking concomitant medications that induce orthostatic hypotension (such as antihypertensives) or are potent CYP1A2 inhibitors [see Drug Interactions ( 7.1 )] and in patients taking duloxetine delayed-release capsules at doses above 60 mg daily. (etykieta leku Duloksetyna, Ostrzeżenia i środki ostrożności)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

If the ECG shows no widening of the QRS or arrhythmia in the presence of hyperkalemia, it is usually sufficient to discontinue Dyrenium (triamterene) and any potassium supplementation, and substitute a thiazide alone. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

Following initiation and titration of Epogen, approximately 25% of patients on dialysis required initiation of or increases in antihypertensive therapy; hypertensive encephalopathy and seizures have been reported in patients with CKD receiving Epogen. (etykieta leku Epoetyna alfa, Ostrzeżenia i środki ostrożności)

Additional reductions in blood pressure may occur when VELETRI is administered with diuretics, antihypertensive agents, or other vasodilators. (etykieta leku Epoprostenol, Interakcje z innymi lekami)

Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (etykieta leku Escytalopram, Ostrzeżenia i środki ostrożności)

Antihypertensive agents clonidine, guanfacine, or moxonidine: Beta blockers also increase the risk of clonidine-, guanfacine-, or moxonidine-withdrawal rebound hypertension. (etykieta leku Esmolol, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

The effects of the following drugs may be potentiated when given together with triamterene: antihypertensive medication, other diuretics, preanesthetic and anesthetic agents, skeletal muscle relaxants (non-depolarizing). (etykieta leku Triamteren, Interakcje z innymi lekami)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (etykieta leku Ezomeprazol, Ostrzeżenia i środki ostrożności)

…hydrochloride desipramine hydrochloride imipramine hydrochloride doxepin carbamazepine cyclobenzaprine HCl amoxapine maprotiline HCl trimipramine maleate protriptyline HCl mirtazapine Phenelzine sulfate should be used with caution in combination with antihypertensive drugs, including thiazide diuretics and β-blockers, since exaggerated hypotensive effects may result. (etykieta leku Fenelzyna, Ostrzeżenia)

…from blood bank (may contain up to 30 mEq of potassium per liter of plasma or up to 65 mEq per liter of whole blood when stored for more than 10 days); low-salt milk (may contain up to 60 mEq of potassium per liter); potassium-containing medications (such as parenteral penicillin G potassium); salt substitutes (most contain substantial amounts of potassium). (etykieta leku Triamteren, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

…treatment with Class 1 and Class III antiarrhythmics, 4) treatment with monoamine oxidase inhibitors (MAOI's), 5) concomitant treatment with other drug products known to prolong the QT interval and 6) electrolyte imbalance, in particular hypokalemia and hypomagnesemia, or concomitant treatment with drugs (e.g., diuretics) that may cause electrolyte imbalance. (etykieta leku Fentanyl, Ostrzeżenia i środki ostrożności)

In addition, when phentermine and topiramate extended-release capsules are used in conjunction with nonpotassium sparing diuretics this may further potentiate potassium-wasting. (etykieta leku Fentermina + topiramat, Ostrzeżenia i środki ostrożności)

Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (etykieta leku Fludrokortyzon, Interakcje z innymi lekami)

An effect of this magnitude should not necessitate a change in the fluconazole dose regimen in subjects receiving concomitant diuretics. (etykieta leku Flukonazol, Interakcje z innymi lekami)

Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (etykieta leku Fluoksetyna, Ostrzeżenia i środki ostrożności)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Diuretics: Use with caution. (etykieta leku Flutykazon + salmeterol, Interakcje z innymi lekami)

Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (etykieta leku Fluwoksamina, Ostrzeżenia i środki ostrożności)

• Xanthine derivatives, steroids, diuretics, or non-potassium sparing diuretics may potentiate hypokalemia or ECG changes. (etykieta leku Formoterol, Interakcje z innymi lekami)

When diuretics are indicated, thiazides are recommended over loop diuretics because the latter inhibit renal tubular secretion, and may impair elimination of FOSCAVIR, potentially leading to toxicity. (etykieta leku Foskarnet, Interakcje z innymi lekami)

Potassium-sparing agents should be used with caution in conjunction with angiotensin-converting enzyme (ACE) inhibitors due to an increased risk of hyperkalemia. (etykieta leku Triamteren, Interakcje z innymi lekami)

If the ECG shows no widening of the QRS or arrhythmia in the presence of hyperkalemia, it is usually sufficient to discontinue Dyrenium (triamterene) and any potassium supplementation, and substitute a thiazide alone. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

Drug Interactions Caution should be used when lithium and diuretics are used concomitantly because diuretic-induced sodium loss may reduce the renal clearance of lithium and increase serum lithium levels with risk of lithium toxicity. (etykieta leku Triamteren, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Caution is advised when haloperidol decanoate is used in combination with drugs known to cause electrolyte imbalance (e.g., diuretics or corticosteroids) because hypokalemia, hypomagnesemia, and hypocalcemia are risk factors for QT prolongation. (etykieta leku Haloperydol, Interakcje z innymi lekami)

If the ECG shows no widening of the QRS or arrhythmia in the presence of hyperkalemia, it is usually sufficient to discontinue Dyrenium (triamterene) and any potassium supplementation, and substitute a thiazide alone. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

Example: Cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Hydrokodon, Interakcje z innymi lekami)

Diuretics : Hydrocodone may reduce the efficacy of diuretics. (etykieta leku Hydrokodon + chlorfenamina, Interakcje z innymi lekami)

Diuretics : Hydrocodone may reduce the efficacy of diuretics. (etykieta leku Hydrokodon + homatropina, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Hydrokodon + paracetamol, Interakcje z innymi lekami)

Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Hydromorfon, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive medications), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (etykieta leku Iloperydon, Ostrzeżenia i środki ostrożności)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with imipramine hydrochloride tablets. (etykieta leku Imipramina, Ostrzeżenia)

If the ECG shows no widening of the QRS or arrhythmia in the presence of hyperkalemia, it is usually sufficient to discontinue Dyrenium (triamterene) and any potassium supplementation, and substitute a thiazide alone. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

Infusion of glucose and insulin has also been used to treat hyperkalemia. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

Infusion of glucose and insulin has also been used to treat hyperkalemia. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

Infusion of glucose and insulin has also been used to treat hyperkalemia. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

Infusion of glucose and insulin has also been used to treat hyperkalemia. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

Infusion of glucose and insulin has also been used to treat hyperkalemia. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

Infusion of glucose and insulin has also been used to treat hyperkalemia. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

Diuretics The electrocardiogram (ECG) changes and/or hypokalemia that may result from the administration of non-potassium sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by β-agonists, especially when the recommended dose of the β-agonist is exceeded. (etykieta leku Ipratropium + salbutamol, Interakcje z innymi lekami)

Hypotension in Volume or Salt-Depleted Patients In patients with an activated renin-angiotensin system, such as volume or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initialization of treatment with AVAPRO. (etykieta leku Irbesartan, Ostrzeżenia i środki ostrożności)

If the ECG shows no widening of the QRS or arrhythmia in the presence of hyperkalemia, it is usually sufficient to discontinue Dyrenium (triamterene) and any potassium supplementation, and substitute a thiazide alone. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

The effects of the following drugs may be potentiated when given together with triamterene: antihypertensive medication, other diuretics, preanesthetic and anesthetic agents, skeletal muscle relaxants (non-depolarizing). (etykieta leku Triamteren, Interakcje z innymi lekami)

Concurrent use with potassium-containing medications, potassium-sparing diuretics and angiotensin-converting enzyme inhibitors (ACE inhibitors) may result in hyperkalemia and cardiac arrhythmias or cardiac arrest. (etykieta leku Jodek potasu, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Symptomatic hypotension is most likely to occur in patients who have been volume and/or salt depleted as a result of prolonged diuretic therapy, dietary salt restriction, dialysis, diarrhea, or vomiting. (etykieta leku Kandesartan, Ostrzeżenia i środki ostrożności)

If the ECG shows no widening of the QRS or arrhythmia in the presence of hyperkalemia, it is usually sufficient to discontinue Dyrenium (triamterene) and any potassium supplementation, and substitute a thiazide alone. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

Potassium-sparing agents should be used with caution in conjunction with angiotensin-converting enzyme (ACE) inhibitors due to an increased risk of hyperkalemia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Elderly patients and patients treated with diuretics are at greater risk of developing hyponatremia. (etykieta leku Karbamazepina, Ostrzeżenia i środki ostrożności)

Symptomatic postural hypotension has occurred when carbidopa, given with levodopa or carbidopa-levodopa combination products, was added to the treatment of a patient receiving antihypertensive drugs. (etykieta leku Karbidopa, Interakcje z innymi lekami)

Antihypertensive drugs: May cause symptomatic postural hypotension. (etykieta leku Karbidopa + lewodopa, Interakcje z innymi lekami)

Antihypertensive Agents Symptomatic postural hypotension has occurred when carbidopa/levodopa was added to the treatment of patients receiving antihypertensive drugs. (etykieta leku Karbidopa + lewodopa + entakapon, Interakcje z innymi lekami)

Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive medications), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (etykieta leku Kariprazyna, Ostrzeżenia i środki ostrożności)

If such symptoms occur, diuretics should be increased and the carvedilol dose should not be advanced until clinical stability resumes [see Dosage and Administration (2) ] . (etykieta leku Karwedilol, Ostrzeżenia i środki ostrożności)

The effects of the following drugs may be potentiated when given together with triamterene: antihypertensive medication, other diuretics, preanesthetic and anesthetic agents, skeletal muscle relaxants (non-depolarizing). (etykieta leku Triamteren, Interakcje z innymi lekami)

The effects of the following drugs may be potentiated when given together with triamterene: antihypertensive medication, other diuretics, preanesthetic and anesthetic agents, skeletal muscle relaxants (non-depolarizing). (etykieta leku Triamteren, Interakcje z innymi lekami)

Diuretics eplerenone The potential increase in plasma concentrations of eplerenone when coadministered with ketoconazole tablets may increase the risk of hyperkalemia and hypotension. (etykieta leku Ketokonazol, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Consider use of diuretics and/or albumin. (etykieta leku Klofarabina, Ostrzeżenia i środki ostrożności)

Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Kodeina, Interakcje z innymi lekami)

Drug Interactions Cholestyramine for Oral Suspension USP may delay or reduce the absorption of concomitant oral medication such as phenylbutazone, warfarin, thiazide diuretics (acidic), or propranolol (basic), as well as tetracycline, penicillin G, phenobarbital, thyroid and thyroxine preparations, estrogens and progestins, and digitalis. (etykieta leku Kolestyramina, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (etykieta leku Kwas zoledronowy, Ostrzeżenia i środki ostrożności)

Quetiapine should be used with particular caution in patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure, or conduction abnormalities), cerebrovascular disease, or conditions which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications). (etykieta leku Kwetiapina, Ostrzeżenia i środki ostrożności)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (etykieta leku Lanzoprazol, Ostrzeżenia i środki ostrożności)

Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk. (etykieta leku Lewomilnacypran, Ostrzeżenia i środki ostrożności)

Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Leworfanol, Interakcje z innymi lekami)

Diuretics The ECG changes or hypokalemia that may result from the administration of non-potassium-sparing diuretics (such as loop and thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. (etykieta leku Lewosalbutamol, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Monitor serum sodium levels regularly in the elderly, in patients taking diuretics, and in other patients at risk of hyponatremia and/or SIADH while taking Linezolid injection. (etykieta leku Linezolid, Ostrzeżenia i środki ostrożności)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Drug Interactions Caution should be used when lithium and diuretics are used concomitantly because diuretic-induced sodium loss may reduce the renal clearance of lithium and increase serum lithium levels with risk of lithium toxicity. (etykieta leku Triamteren, Interakcje z innymi lekami)

Potassium-sparing agents should be used with caution in conjunction with angiotensin-converting enzyme (ACE) inhibitors due to an increased risk of hyperkalemia. (etykieta leku Triamteren, Interakcje z innymi lekami)

If the ECG shows no widening of the QRS or arrhythmia in the presence of hyperkalemia, it is usually sufficient to discontinue Dyrenium (triamterene) and any potassium supplementation, and substitute a thiazide alone. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

Hypotension in Volume- or Salt-Depleted Patients In patients with an activated renin-angiotensin system, such as volume- or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of treatment with COZAAR. (etykieta leku Losartan, Ostrzeżenia i środki ostrożności)

If the ECG shows no widening of the QRS or arrhythmia in the presence of hyperkalemia, it is usually sufficient to discontinue Dyrenium (triamterene) and any potassium supplementation, and substitute a thiazide alone. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive drugs), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and patients… (etykieta leku Lumateperon, Ostrzeżenia i środki ostrożności)

Patients at increased risk of these adverse reactions or at increased risk of developing complications from hypotension include those with dehydration, hypovolemia, treatment with antihypertensive medication, history of cardiovascular disease (e.g., heart failure, myocardial infarction, ischemia, or conduction abnormalities), history of cerebrovascular disease,… (etykieta leku Lurazydon, Ostrzeżenia i środki ostrożności)

The action of Mecamylamine HCl may be potentiated by anesthesia, other antihypertensive drugs and alcohol. (etykieta leku Mekamylamina, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Closely monitor patients with risk factors for development of prolonged QT interval (e.g., cardiac hypertrophy, concomitant diuretic use, hypokalemia, hypomagnesemia), a history of cardiac conduction abnormalities, and those taking medications affecting cardiac conduction. (etykieta leku Metadon, Ostrzeżenia i środki ostrożności)

The effects of the following drugs may be potentiated when given together with triamterene: antihypertensive medication, other diuretics, preanesthetic and anesthetic agents, skeletal muscle relaxants (non-depolarizing). (etykieta leku Triamteren, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

The effects of the following drugs may be potentiated when given together with triamterene: antihypertensive medication, other diuretics, preanesthetic and anesthetic agents, skeletal muscle relaxants (non-depolarizing). (etykieta leku Triamteren, Interakcje z innymi lekami)

The effects of the following drugs may be potentiated when given together with triamterene: antihypertensive medication, other diuretics, preanesthetic and anesthetic agents, skeletal muscle relaxants (non-depolarizing). (etykieta leku Triamteren, Interakcje z innymi lekami)

If such symptoms occur, increase diuretics and restore clinical stability before advancing the dose of Metoprolol Tartrate Tablets [see Dosage and Administration (2) ]. (etykieta leku Metoprolol, Ostrzeżenia i środki ostrożności)

If the ECG shows no widening of the QRS or arrhythmia in the presence of hyperkalemia, it is usually sufficient to discontinue Dyrenium (triamterene) and any potassium supplementation, and substitute a thiazide alone. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

Antihypertensive Drugs: Monitor blood pressure. (etykieta leku Metylofenidat, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Geriatric Use ( 8.5 )] . (etykieta leku Milnacypran, Ostrzeżenia i środki ostrożności)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia [see Use in Specific Populations (8.5) ] . (etykieta leku Mirtazapina, Ostrzeżenia i środki ostrożności)

However, a retrospective analysis of the use of antihypertensive medication in these studies showed that a greater proportion of patients on PROVIGIL required new or increased use of antihypertensive medications (2.4%) compared to patients on placebo (0.7%). (etykieta leku Modafinil, Ostrzeżenia i środki ostrożności)

Potassium-sparing agents should be used with caution in conjunction with angiotensin-converting enzyme (ACE) inhibitors due to an increased risk of hyperkalemia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Morfina, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Although beta-blockers should be avoided in overt congestive heart failure, if necessary, they can be used with caution in patients with a history of failure who are well-compensated, usually with digitalis and diuretics. (etykieta leku Nadolol, Ostrzeżenia)

…from blood bank (may contain up to 30 mEq of potassium per liter of plasma or up to 65 mEq per liter of whole blood when stored for more than 10 days); low-salt milk (may contain up to 60 mEq of potassium per liter); potassium-containing medications (such as parenteral penicillin G potassium); salt substitutes (most contain substantial amounts of potassium). (etykieta leku Triamteren, Interakcje z innymi lekami)

Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Nalbufina, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Antihypertensive Therapy Niacin may potentiate the effects of ganglionic blocking agents and vasoactive drugs resulting in postural hypotension. (etykieta leku Niacyna (kwas nikotynowy), Interakcje z innymi lekami)

Other Diuretics, PDE5 inhibitors, alpha-methyldopa: Nifedipine may increase the blood pressure lowering effect of these concomitantly administered agents. (etykieta leku Nifedypina, Interakcje z innymi lekami)

Blood Pressure Lowering Drugs Nimodipine may increase the blood pressure lowering effect of concomitantly administered anti-hypertensives such as diuretics, beta-blockers, ACE inhibitors, angiotensin receptor blockers, other calcium channel blockers, α-adrenergic blockers, PDE5 inhibitors, and α-methyldopa. (etykieta leku Nimodypina, Interakcje z innymi lekami)

Antihypertensives: Possible additive hypotensive effects. (etykieta leku Nitrogliceryna, Interakcje z innymi lekami)

…from blood bank (may contain up to 30 mEq of potassium per liter of plasma or up to 65 mEq per liter of whole blood when stored for more than 10 days); low-salt milk (may contain up to 60 mEq of potassium per liter); potassium-containing medications (such as parenteral penicillin G potassium); salt substitutes (most contain substantial amounts of potassium). (etykieta leku Triamteren, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Oksykodon, Interakcje z innymi lekami)

Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Oksykodon + paracetamol, Interakcje z innymi lekami)

Examples: butorphanol, nalbuphine, pentazocine, buprenorphine Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Oksymorfon, Interakcje z innymi lekami)

…of myocardial infarction or ischemia, heart failure, or conduction abnormalities), cerebrovascular disease, and conditions which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications) where the occurrence of syncope, or hypotension and/or bradycardia might put the patient at increased medical risk. (etykieta leku Olanzapina, Ostrzeżenia i środki ostrożności)

…and fluoxetine capsules should be used with particular caution in patients with known cardiovascular disease (history of myocardial infarction or ischemia, heart failure, or conduction abnormalities), cerebrovascular disease, or conditions that would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications). (etykieta leku Olanzapina + fluoksetyna, Ostrzeżenia i środki ostrożności)

Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Olicerydyna, Interakcje z innymi lekami)

Hypotension in Volume- or Salt-Depleted Patients In patients with an activated renin-angiotensin-aldosterone system, such as volume- and/or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may be anticipated after initiation of treatment with Benicar. (etykieta leku Olmesartan, Ostrzeżenia i środki ostrożności)

If the ECG shows no widening of the QRS or arrhythmia in the presence of hyperkalemia, it is usually sufficient to discontinue Dyrenium (triamterene) and any potassium supplementation, and substitute a thiazide alone. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

If the ECG shows no widening of the QRS or arrhythmia in the presence of hyperkalemia, it is usually sufficient to discontinue Dyrenium (triamterene) and any potassium supplementation, and substitute a thiazide alone. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (etykieta leku Omeprazol, Ostrzeżenia i środki ostrożności)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (etykieta leku Omeprazol + wodorowęglan sodu, Ostrzeżenia i środki ostrożności)

The effects of the following drugs may be potentiated when given together with triamterene: antihypertensive medication, other diuretics, preanesthetic and anesthetic agents, skeletal muscle relaxants (non-depolarizing). (etykieta leku Triamteren, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Use ERZOFRI with caution in patients with known cardiovascular disease (e.g., heart failure, history of myocardial infarction or ischemia, conduction abnormalities), cerebrovascular disease, or conditions that predispose the patient to hypotension (e.g., dehydration, hypovolemia, and treatment with antihypertensive medications). (etykieta leku Paliperydon, Ostrzeżenia i środki ostrożności)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (etykieta leku Pantoprazol, Ostrzeżenia i środki ostrożności)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Paracetamol + kodeina, Interakcje z innymi lekami)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SNRIs and SSRIs. [see Use in Specific Populations ( 8.5 )]. (etykieta leku Paroksetyna, Ostrzeżenia i środki ostrożności)

The risk may be increased when Paricalcitol Injection is used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (etykieta leku Parykalcytol, Ostrzeżenia i środki ostrożności)

Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (etykieta leku Pazopanib, Ostrzeżenia i środki ostrożności)

Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Pentazocyna + nalokson, Interakcje z innymi lekami)

Small decreases in blood pressure have been observed in some patients treated with pentoxifylline extended-release tablets; periodic systemic blood pressure monitoring is recommended for patients receiving concomitant antihypertensive therapy. (etykieta leku Pentoksyfilina, Interakcje z innymi lekami)

Potassium-sparing agents should be used with caution in conjunction with angiotensin-converting enzyme (ACE) inhibitors due to an increased risk of hyperkalemia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Examples: Cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Petydyna, Interakcje z innymi lekami)

Although beta-blockers should be avoided in overt congestive heart failure, if necessary, pindolol tablets can be used with caution in patients with a history of failure who are well-compensated, usually with digitalis and diuretics. (etykieta leku Pindolol, Ostrzeżenia)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

…from blood bank (may contain up to 30 mEq of potassium per liter of plasma or up to 65 mEq per liter of whole blood when stored for more than 10 days); low-salt milk (may contain up to 60 mEq of potassium per liter); potassium-containing medications (such as parenteral penicillin G potassium); salt substitutes (most contain substantial amounts of potassium). (etykieta leku Triamteren, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Diuretics Clinical Impact : Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Pokrzyk wilcza jagoda (belladonna) + opium, Interakcje z innymi lekami)

Sodium polystyrene sulfonate may be administered to enhance the excretion of excess potassium. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

Syncopal episodes have usually occurred within 30 to 90 minutes of the initial dose of the drug; occasionally, they have been reported in association with rapid dosage increases or the introduction of another antihypertensive drug into the regimen of a patient taking high doses of prazosin hydrochloride capsules. (etykieta leku Prazosyna, Ostrzeżenia)

Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etykieta leku Prochlorperazyna, Środki ostrożności)

Diuretics : Codeine may reduce the efficacy of diuretics. (etykieta leku Prometazyna + kodeina, Interakcje z innymi lekami)

The effects of the following drugs may be potentiated when given together with triamterene: antihypertensive medication, other diuretics, preanesthetic and anesthetic agents, skeletal muscle relaxants (non-depolarizing). (etykieta leku Triamteren, Interakcje z innymi lekami)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (etykieta leku Rabeprazol, Ostrzeżenia i środki ostrożności)

Potassium-sparing agents should be used with caution in conjunction with angiotensin-converting enzyme (ACE) inhibitors due to an increased risk of hyperkalemia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Consider the potential for symptomatic hypotension or ischemia in patients with hypovolemia, severe left ventricular outflow obstruction, resting hypotension, autonomic dysfunction, or concomitant treatment with antihypertensives or strong CYP and P-gp/BCRP inhibitors [see Drug Interactions (7.2) and Clinical Pharmacology (12.3) ] . (etykieta leku Riocyguat, Ostrzeżenia i środki ostrożności)

Clinically significant hypotension has been observed with concomitant use of oral RISPERDAL and antihypertensive medication. (etykieta leku Rysperydon, Ostrzeżenia i środki ostrożności)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Patients with an activated renin-angiotensin system, such as volume- and/or salt-depleted patients (e.g., those being treated with high doses of diuretics), are at greater risk. (etykieta leku Sakubitryl + walsartan, Ostrzeżenia i środki ostrożności)

Diuretics: Use with caution. (etykieta leku Salbutamol, Interakcje z innymi lekami)

• Diuretics: Use with caution. (etykieta leku Salmeterol, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (etykieta leku Sertralina, Ostrzeżenia i środki ostrożności)

The effects of the following drugs may be potentiated when given together with triamterene: antihypertensive medication, other diuretics, preanesthetic and anesthetic agents, skeletal muscle relaxants (non-depolarizing). (etykieta leku Triamteren, Interakcje z innymi lekami)

Consider temporary or permanent discontinuation for severe or persistent hypertension despite antihypertensive therapy. (etykieta leku Sorafenib, Ostrzeżenia i środki ostrożności)

Special attention should be given to electrolyte and acid-base balance in patients experiencing severe or prolonged diarrhea or patients receiving concomitant diuretic drugs. (etykieta leku Sotalol, Ostrzeżenia i środki ostrożności)

Prolonged Neuromuscular Block in Patients with Hypokalemia or Hypocalcemia Neuromuscular blockade may be prolonged in patients with hypokalemia (e.g., after severe vomiting, diarrhea, digitalisation and diuretic therapy) or hypocalcemia (e.g., after massive transfusions). (etykieta leku Suksametonium, Ostrzeżenia i środki ostrożności)

Drug Interactions In elderly patients concurrently receiving certain diuretics, primarily thiazides, an increased incidence of thrombocytopenia with purpura has been reported. (etykieta leku Sulfametoksazol + trimetoprim, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Initiate and/or adjust antihypertensive therapy as appropriate. (etykieta leku Sunitynib, Ostrzeżenia i środki ostrożności)

Caution is advised when SILDENAFIL ORAL FILM is co-administered with alpha-blockers or antihypertensives. (etykieta leku Syldenafil, Ostrzeżenia i środki ostrożności)

However, patients in the Phase 3 clinical studies taking concomitant antihypertensive medications with silodosin capsules did not experience a significant increase in the incidence of syncope, dizziness, or orthostasis. (etykieta leku Sylodosyna, Ostrzeżenia i środki ostrożności)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Dyrenium (triamterene) may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be necessary during and/or after therapy; concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (etykieta leku Triamteren, Interakcje z innymi lekami)

• Hypertension: May require antihypertensive therapy; monitor relevant drug interactions. (etykieta leku Takrolimus, Ostrzeżenia i środki ostrożności)

…use of skeletal muscle relaxants and opioids, consider prescribing naloxone for the emergency treatment of opioid overdose [see Dosage and Administration (2.2) , Warnings and Precautions (5.2 , 5.3) ] Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Tapentadol, Interakcje z innymi lekami)

Hypotension In patients with an activated renin-angiotensin system, such as volume- or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of therapy with telmisartan tablets. (etykieta leku Telmisartan, Ostrzeżenia i środki ostrożności)

Hypotension Telmisartan In patients with an activated renin-angiotensin system, such as volume- or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of therapy with telmisartan and amlodipine tablets. (etykieta leku Telmisartan + amlodypina, Ostrzeżenia i środki ostrożności)

If the ECG shows no widening of the QRS or arrhythmia in the presence of hyperkalemia, it is usually sufficient to discontinue Dyrenium (triamterene) and any potassium supplementation, and substitute a thiazide alone. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

Risk of Hypotension with Concomitant Use of Other Antihypertensive Agents and Phospodiesterase Type 5 Inhibitors (PDE5-I): Concomitant administration of TEZRULY with antihypertensives or phosphodiesterase-5 (PDE-5) inhibitors can result in additive blood pressure lowering effects and symptomatic hypotension (5.3). (etykieta leku Terazosyna, Ostrzeżenia i środki ostrożności)

Diuretics The ECG changes and/or hypokalemia that may result from the administration of non-potassium sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. (etykieta leku Terbutalina, Środki ostrożności)

In patients with hypertension on antihypertensive therapy, TLANDO increased the mean systolic/diastolic BP by 4.8/1.6 mm Hg from baseline. [see Adverse Reactions ( 6.1 )] . (etykieta leku Testosteron, Ostrzeżenia i środki ostrożności)

Some diuretics can enhance aminoglycoside toxicity by altering antibiotic concentrations in serum and tissue. (etykieta leku Tobramycyna, Interakcje z innymi lekami)

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene. (etykieta leku Triamteren, Interakcje z innymi lekami)

Co-administration of diuretics also increases the risk of too rapid correction of serum sodium and such patients should undergo close monitoring of serum sodium. (etykieta leku Tolwaptan, Ostrzeżenia i środki ostrożności)

Drug Interactions Caution should be used when lithium and diuretics are used concomitantly because diuretic-induced sodium loss may reduce the renal clearance of lithium and increase serum lithium levels with risk of lithium toxicity. (etykieta leku Triamteren, Interakcje z innymi lekami)

Drugs that decrease renal calcium excretion, e.g., thiazide diuretics, may increase the risk of hypercalcemia in patients receiving FARESTON. (etykieta leku Toremifen, Interakcje z innymi lekami)

Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Tramadol, Interakcje z innymi lekami)

Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Tramadol + paracetamol, Interakcje z innymi lekami)

Potassium-sparing agents should be used with caution in conjunction with angiotensin-converting enzyme (ACE) inhibitors due to an increased risk of hyperkalemia. (etykieta leku Triamteren, Interakcje z innymi lekami)

Concomitant use with an antihypertensive may require a reduction in the dose of the antihypertensive drug. (etykieta leku Trazodon, Ostrzeżenia i środki ostrożności)

Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etykieta leku Trifluoperazyna, Środki ostrożności)

Infusion of glucose and insulin has also been used to treat hyperkalemia. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

The effects of the following drugs may be potentiated when given together with triamterene: antihypertensive medication, other diuretics, preanesthetic and anesthetic agents, skeletal muscle relaxants (non-depolarizing). (etykieta leku Triamteren, Interakcje z innymi lekami)

• Diuretics: Use with caution. (etykieta leku Umeklidynium + wilanterol, Interakcje z innymi lekami)

In patients with an activated renin-angiotensin system, such as volume- and/or salt-depleted patients receiving high doses of diuretics, symptomatic hypotension may occur. (etykieta leku Walsartan, Ostrzeżenia i środki ostrożności)

If the ECG shows no widening of the QRS or arrhythmia in the presence of hyperkalemia, it is usually sufficient to discontinue Dyrenium (triamterene) and any potassium supplementation, and substitute a thiazide alone. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

Vardenafil hydrochloride tablets can potentiate the hypotensive effects of nitrates, alpha- blockers, and antihypertensives. (etykieta leku Wardenafil, Interakcje z innymi lekami)

Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (etykieta leku Wenlafaksyna, Ostrzeżenia i środki ostrożności)

Control patients with milder ventricular dysfunction, if possible, with optimum doses of digitalis and/or diuretics before verapamil treatment is started [see Drug Interactions ( 7.5 )] . (etykieta leku Werapamil, Ostrzeżenia i środki ostrożności)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs and SNRIs [see Use in Specific Populations ( 8.5 )] . (etykieta leku Wilazodon, Ostrzeżenia i środki ostrożności)

Also, patients taking diuretics or who are otherwise volume-depleted can be at greater risk. (etykieta leku Wortioksetyna, Ostrzeżenia i środki ostrożności)

Hypokalemia may result from diuretic therapy, diarrhea, and other causes. (etykieta leku Zyprazydon, Ostrzeżenia i środki ostrożności)

Coadministration of 1 Dyazide (triamterene/hydrochlorothiazide) resulted in a higher plasma amantadine hydrochloride concentration in a 61-year old man receiving amantadine hydrochloride 100 mg TID for Parkinson's disease. (etykieta leku Amantadyna, Interakcje z innymi lekami)

Patients required intervention with a diuretic, fluid management, or, in some cases, hospitalization for decompensating heart failure. (etykieta leku Ambrisentan, Ostrzeżenia i środki ostrożności)

In hypertensive patients who have congestive heart failure controlled by digitalis and diuretics, beta-blockers should be administered cautiously. (etykieta leku Betaksolol, Ostrzeżenia)

Patients required intervention with a diuretic, fluid management, or hospitalization for decompensating heart failure. (etykieta leku Bosentan, Ostrzeżenia i środki ostrożności)

In such cases, butorphanol should be discontinued and the hypertension treated with antihypertensive drugs. (etykieta leku Butorfanol, Ostrzeżenia)

Fluid retention events were typically managed by supportive care measures that may include diuretics or short courses of steroids. (etykieta leku Dazatynib, Ostrzeżenia i środki ostrożności)

Antihypertensives Amphetamines may antagonize the hypotensive effects of antihypertensives. (etykieta leku Deksamfetamina, Interakcje z innymi lekami)

If other contraceptive methods are not suitable, hormonal contraceptive therapy may continue combined with antihypertensive therapy. (etykieta leku Dezogestrel + etynyloestradiol, Ostrzeżenia)

Drug Interactions There was no evidence of drug interactions in clinical studies in which dobutamine was administered concurrently with other drugs, including digitalis preparations, furosemide, spironolactone, lidocaine, glyceryl trinitrate, isosorbide dinitrate, morphine, atropine, heparin, protamine, potassium chloride, folic acid, and acetaminophen. (etykieta leku Dobutamina, Interakcje z innymi lekami)

Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (etykieta leku Docetaksel, Ostrzeżenia i środki ostrożności)

Hypokalemia and Hypomagnesemia with Potassium-Depleting Diuretics Hypokalemia or hypomagnesemia may occur with concomitant administration of potassium-depleting diuretics. (etykieta leku Dronedaron, Ostrzeżenia i środki ostrożności)

Examples: α-adrenergic antagonists, β-adrenergic receptor antagonists, reserpine, quinidine, mephentermine Other Drug Interactions G u anethidine C linical Impact: Ephedrine may inhibit the neuron blockage produced by guanethidine, resulting in loss of antihypertensive effectiveness. (etykieta leku Efedryna, Interakcje z innymi lekami)

In addition to discontinuation of the drug, diuretic therapy may be required. (etykieta leku Estrogeny estryfikowane + metylotestosteron, Ostrzeżenia)

…clinical studies with acetaminophen, acetylsalicylic acid, α-blockers, angiotensin-converting enzyme (ACE) inhibitors, analgesics, anti-convulsants, beta-adrenergic blocking agents, diuretics, calcium channel blockers, cardiac nitrates, HMG-CoA reductase inhibitors, nonsteroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, H 2 antagonists and quinolone anti-infectives… (etykieta leku Finasteryd, Interakcje z innymi lekami)

Flecainide acetate has been used in a large number of patients receiving diuretics without apparent interaction. (etykieta leku Flekainid, Interakcje z innymi lekami)

For tachyarrhythmia, infuse 44 mEq of sodium bicarbonate or 10 mL of 10% calcium gluconate or calcium chloride over several minutes. (etykieta leku Triamteren, Ostrzeżenia i środki ostrożności)

Drug interactions may occur when anticholinergics are used with the following medications: antacids, antidiarrheals (adsorbent), other anticholinergics, antimyasthenics, cyclopropane, haloperidol, ketoconazole, metoclopramide, opioid (narcotic) analgesics, and potassium chloride. (etykieta leku Hioscyjamina, Interakcje z innymi lekami)

When other potent parenteral antihypertensive drugs, such as diazoxide, are used in combination with hydralazine, patients should be continuously observed for several hours for any excessive fall in blood pressure. (etykieta leku Hydralazyna, Interakcje z innymi lekami)

ACE Inhibitors FIRAZYR is a bradykinin B2 receptor antagonist and thereby has the potential to have a pharmacodynamic interaction with ACE inhibitors where FIRAZYR may attenuate the antihypertensive effect of ACE inhibitors. (etykieta leku Ikatybant, Interakcje z innymi lekami)

Weigh patients regularly and manage unexpected rapid weight gain by drug interruption and diuretics. (etykieta leku Imatynib, Ostrzeżenia i środki ostrożności)

In a study in hypertensive patients, addition of isradipine to existing hydrochlorothiazide therapy did not result in any unexpected adverse effects, and isradipine had an additional antihypertensive effect. (etykieta leku Isradypina, Interakcje z innymi lekami)

Acthar Gel may accentuate the electrolyte loss associated with diuretic therapy. (etykieta leku Kortykotropina, Interakcje z innymi lekami)

Postmarketing cases of edema and fluid retention occurring within weeks of starting OPSUMIT, some requiring intervention with a diuretic or hospitalization for decompensated heart failure, have been reported [see Adverse Reactions (6.2) ] . (etykieta leku Macytentan, Ostrzeżenia i środki ostrożności)

In a large compassionate use program mexiletine has been used concurrently with commonly employed antianginal, antihypertensive, and anticoagulant drugs without observed interactions. (etykieta leku Meksyletyna, Interakcje z innymi lekami)

Drug Interactions When methyldopa is used with other antihypertensive drugs, potentiation of antihypertensive effect may occur. (etykieta leku Metyldopa, Interakcje z innymi lekami)

Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

In addition to discontinuation of the drug, diuretic therapy may be required. (etykieta leku Metylotestosteron, Ostrzeżenia)

…for Drug Interaction: It appears possible, although there is no supporting experimental evidence, that the high renal clearance of desglymidodrine (a base) is due to active tubular secretion by the base-secreting system also responsible for the secretion of such drugs as metformin, cimetidine, ranitidine, procainamide, triamterene, flecainide, and quinidine. (etykieta leku Midodryna, Środki ostrożności)

…been observed in limited experience with patients in whom milrinone was used concurrently with the following drugs: digitalis glycosides; lidocaine, quinidine; hydralazine, prazosin; isosorbide dinitrate, nitroglycerin; chlorthalidone, furosemide, hydrochlorothiazide, spironolactone; captopril; heparin, warfarin, diazepam, insulin; and potassium supplements. (etykieta leku Milrinon, Interakcje z innymi lekami)

Hypertensive patients, and patients concomitantly receiving other antihypertensive medications, may be more sensitive to the effects of sodium nitroprusside than normal subjects. (etykieta leku Nitroprusydek sodu, Ostrzeżenia)

The blood pressure effect of SULAR tended to be greater in patients on atenolol than in patients on no other antihypertensive therapy. (etykieta leku Nizoldypina, Interakcje z innymi lekami)

The antihypertensive action of guanethidine and similar agents may be blocked. (etykieta leku Nortryptylina, Ostrzeżenia)

Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)

Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizon, Interakcje z innymi lekami)

Protriptyline may block the antihypertensive effect of guanethidine or similarly acting compounds. (etykieta leku Protryptylina, Ostrzeżenia)

Potentiation of the action of sulfonylurea hypoglycemic agents, thiazide diuretics and uricosuric agents may also be noted. (etykieta leku Sulfadiazyna, Interakcje z innymi lekami)

There is no information available from adequate drug-drug interaction studies with the following classes of drugs: oral contraceptives, hormone replacement therapies, hypoglycemics, phenytoins, thiazide diuretics, and calcium channel blockers. (etykieta leku Terbinafina, Interakcje z innymi lekami)

Amphotericin B injection and potassium-depleting agents: When corticosteroids are administered concomitantly with potassium-depleting agents ( i.e., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Triamcynolon, Interakcje z innymi lekami)

Loop Diuretics Concomitant administration of a loop diuretic had no effect on the calcium-lowering action of pamidronate disodium. (etykieta leku Kwas pamidronowy, Interakcje z innymi lekami)