Olanzapina + fluoksetyna i Orfenadryna + kwas acetylosalicylowy + kofeina: interakcja

Use with NSAIDs, aspirin, warfarin, or other drugs that affect coagulation may potentiate the risk of gastrointestinal or other bleeding ( 5.16 )

Patients should be cautioned about the increased risk of bleeding associated with the concomitant use of olanzapine and fluoxetine capsules and NSAIDs, aspirin, or other drugs that affect coagulation [see Drug Interactions ( 7.4 )] .

Drugs that Interfere with Hemostasis : (e.g., NSAIDs, Aspirin, Warfarin, etc.): May potentiate the risk of bleeding ( 7.4 )

Epidemiological studies of the case-control and cohort design that have demonstrated an association between use of psychotropic drugs that interfere with serotonin reuptake and the occurrence of upper gastrointestinal bleeding have also shown that concurrent use of an NSAID or aspirin may potentiate this risk of bleeding.

Anticholinergic (antimuscarinic) Effects : Use with caution with other anticholinergic drugs and in patients with urinary retention, prostatic hypertrophy, constipation, history of paralytic ileus or related conditions ( 5.21 )