Budesonid ve formoterol ve Flutikazon ve salmeterol etkileşimi
Budesonid ve formoterol ve Flutikazon ve salmeterol: her iki reçeteleme etiketi de bu kombinasyonu kontrendikasyon, kutulu uyarı veya kaçınma talimatı gibi en güçlü ifadelerle işaretliyor.
Reçeteyi yazan hekimin yönlendirmesi olmadan birlikte kullanmayın. Aşağıdaki etiket ifadeleri, FDA'nın kullandığı en güçlü ifadelerdir.
FDA etiketleri ne diyor
Kaynak: Flutikazon ve salmeterol (Fluticasone Propionate and Salmeterol) etiketi · yürürlük tarihi 2025-08-21
Avoid Excessive Use of Fluticasone Propionate/Salmeterol and Avoid Use with Other Long-Acting Beta 2 -Agonists Fluticasone Propionate/Salmeterol MDPI should not be used more often than recommended, at higher doses than recommended, or in conjunction with other medicines containing LABA, as an overdose may result.
In this situation, the patient requires immediate reevaluation with reassessment of the treatment regimen, giving special consideration to the possible need for replacing the current strength of Fluticasone Propionate/Salmeterol MDPI with a higher strength, adding additional inhaled corticosteroid, or initiating systemic corticosteroids.
Three (3) trials included adult and adolescent subjects aged 12 years and older: 1 trial compared budesonide/formoterol to budesonide, 1 trial compared fluticasone propionate/salmeterol inhalation powder to fluticasone propionate inhalation powder, and 1 trial compared mometasone furoate/formoterol to mometasone furoate.
Patients using Fluticasone Propionate/Salmeterol MDPI should not use another medicine containing a LABA (e.g., salmeterol, formoterol fumarate, arformoterol tartrate, indacaterol) for any reason.
Cases of serious eosinophilic conditions have also been reported with other inhaled corticosteroids in this clinical setting.
Kaynak: Budesonid ve formoterol (Budesonide and Formoterol Fumarate Dihydrate) etiketi · yürürlük tarihi 2026-04-24
Serious Asthma-Related Events – Hospitalizations, Intubations and Death Use of LABA as monotherapy (without ICS) for asthma is associated with an increased risk of asthma-related death [see Salmeterol Multicenter Asthma Research Trial (SMART) ].
…intubation (endotracheal) 1 2 Asthma-related hospitalization (≥24-hour stay) 115 105 ICS = Inhaled Corticosteroid, LABA = Long-acting Beta2-adrenergic Agonist The pediatric safety trial included 6208 pediatric patients 4 to 11 years of age who received ICS/LABA (fluticasone propionate /salmeterol inhalation powder) or ICS (fluticasone propionate inhalation powder).
Salmeterol Multicenter Asthma Research Trial (SMART) A 28-week, placebo-controlled U.S. trial that compared the safety of salmeterol with placebo, each added to usual asthma therapy, showed an increase in asthma-related deaths in patients receiving salmeterol (13/13,176 in patients treated with salmeterol vs. 3/13,179 in patients treated with placebo; relative…
Use with additional long-acting beta 2 -agonist: Do not use in combination because of risk of overdose.
In this situation, the patient requires immediate re-evaluation with reassessment of the treatment regimen, giving special consideration to the possible need for replacing the current strength of budesonide and formoterol fumarate dihydrate with a higher strength, adding additional inhaled corticosteroid, or initiating systemic corticosteroids.
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Sorgulama aracında açTıbbi tavsiye değildir. Interaction Checker, FDA etiket metinlerini ve NIH bilgi sayfalarını alıntılar. Bir etkileşimin sizin için önemli olup olmadığı dozlara, zamanlamaya, böbrek ve karaciğer fonksiyonuna ve diğer sağlık durumlarına bağlıdır. Bir eczacıya veya reçeteyi yazan hekime danışarak doğrulayın.