Kinin ve Süksinilkolin etkileşimi

Avoid concomitant use with neuromuscular blocking agents.

Concomitant Use of Neuromuscular Blocking Agents The use of neuromuscular blocking agents should be avoided in patients receiving quinine sulfate.

Although there are no clinical reports with succinylcholine or tubocurarine, quinine may also potentiate neuromuscular blockade when used with these drugs [see DRUG INTERACTIONS ( 7.2 )] .

Quinine may also enhance the neuromuscular blocking effects of succinylcholine and tubocurarine [see WARNINGS AND PRECAUTIONS ( 5.5 )] .

Neuromuscular Blocking Agents (Pancuronium, Succinylcholine, Tubocurarine) In one report, quinine potentiated neuromuscular blockade in a patient who received pancuronium during an operative procedure, and subsequently (3 hours after receiving pancuronium) received quinine 1800 mg daily.

…the Neuromuscular Blocking Action of Succinylcholine : promazine, oxytocin, aprotinin, certain non-penicillin antibiotics, quinidine, β-adrenergic blockers, procainamide, lidocaine, trimethaphan, lithium carbonate, magnesium salts, quinine, chloroquine, isoflurane, desflurane, metoclopramide, terbutaline, and drugs that reduce plasma cholinesterase activity.

…Action of QUELICIN Drugs that may enhance the neuromuscular blocking action of succinylcholine include: promazine, oxytocin, aprotinin, certain non-penicillin antibiotics, quinidine, β-adrenergic blockers, procainamide, lidocaine, trimethaphan, lithium carbonate, magnesium salts, quinine, chloroquine, isoflurane, desflurane, metoclopramide, and terbutaline.