التداخل بين أدينوزين وأسبرين وديبيريدامول

Drug Interaction Study Information Obtained From Literature Adenosinergic agents (e.g. adenosine, regadenoson) Dipyridamole has been reported to increase the plasma levels and cardiovascular effects of adenosine.

Adjustment of adenosine dosage may be necessary.

Dipyridamole also increases the cardiovascular effects of regadenoson, an adenosine A 2A -receptor agonist.

…suggests that patients being treated with aspirin and extended-release dipyridamole who also require pharmacological stress testing with intravenous dipyridamole or other adenosinergic agents (e.g. adenosine, regadenoson) should interrupt aspirin and extended-release dipyridamole capsules for 48 hours prior to stress testing [see Drug Interactions ( 7.1 )].

Nucleoside transport inhibitors such as dipyridamole can increase the activity of adenosine ( 7.1 )

The vasoactive effects of adenosine are potentiated by nucleoside transport inhibitors such as dipyridamole.

The safety and efficacy of adenosine in the presence of dipyridamole has not been systematically evaluated.