التداخل بين الكحول وغليبيزيد وميتفورمين

…lactic acidosis include renal impairment, concomitant use of certain drugs (e.g., carbonic anhydrase inhibitors such as topiramate), age 65 years old or greater, having a radiological study with contrast, surgery and other procedures, hypoxic states (e.g., acute congestive heart failure), excessive alcohol intake, hepatic impairment, and mitochondrial disease.

Excessive Alcohol intake —Alcohol is known to potentiate the effect of metformin on lactate metabolism.

The risk of hypoglycemia is increased when caloric intake is deficient, when strenuous exercise is not compensated by caloric supplementation, or during concomitant use with other glucose-lowering agents or ethanol.

Alcohol Alcohol is known to potentiate the effect of metformin on lactate metabolism.

Patients, therefore, should be warned against excessive alcohol intake, acute or chronic, while receiving glipizide and metformin hydrochloride.

الكحول قد يسبب انخفاض سكر الدم مع الإنسولين أو السلفونيل يوريا، والشرب بكثرة مع ميتفورمين يرفع خطر الحماض اللبني.

النص الأصلي للنشرة (بالإنجليزية) Alcohol can cause low blood sugar with insulin or sulfonylureas, and heavy drinking with metformin raises the risk of lactic acidosis.