التداخل بين الكحول وميثيل بريدنيزولون

DEPO-MEDROL is contraindicated for use in premature infants because the formulation contains benzyl alcohol (see WARNINGS and PRECAUTIONS: Pediatric Use ).

There have been rare reports of deaths, primarily in preterm infants, associated with exposure to excessive amounts of benzyl alcohol.

Exposure to excessive amounts of benzyl alcohol has been associated with toxicity (hypotension, metabolic acidosis), particularly in neonates, and an increased incidence of kernicterus, particularly in small preterm infants.

The amount of benzyl alcohol in medications is usually considered negligible compared to that received in flush solutions containing benzyl alcohol.

Administration of high dosages of medications containing this preservative must take into account the total amount of benzyl alcohol administered.