التداخل بين أمينوفيلين ودروسبيرينون وإيثينيل إستراديول

…studies, administration of a hormonal contraceptive containing EE did not lead to any increase or only to a weak increase in plasma concentrations of CYP3A4 substrates (e.g., midazolam) while plasma concentrations of CYP2C19 substrates (e.g., omeprazole and voriconazole) and CYP1A2 substrates (e.g., theophylline and tizanidine) can have a weak or moderate increase.

Estrogen Estrogen containing oral contraceptives decrease theophylline clearance in a dose-dependent fashion.